CD40-independent help by memory CD4 T cells induces pathogenic alloantibody but does not lead to long-lasting humoral immunity

American Journal of Transplantation

Volumn 13, Issue 11, 2013, Pages 2831-2841

  Rabant, M ^a,b   Gorbacheva, V ^a   Fan, R ^a   Yu, H ^a   Valujskikh, A ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

Alloantibody; CD40 costimulation; memory T cells

Indexed keywords

ALLOANTIBODY; CD3 ANTIGEN; CD40 ANTIGEN; CD40 LIGAND; COMPLEMENT C4D; COMPLEMENT COMPONENT C4; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2B; IMMUNOGLOBULIN G2C; IMMUNOGLOBULIN G3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY BLOOD LEVEL; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ANTIBODY TITER; ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE; CARDIAC GRAFT REJECTION; CD4+ T LYMPHOCYTE; CELL INTERACTION; CONTROLLED STUDY; FEMALE; GERMINAL CENTER; GRAFT RECIPIENT; HEART GRAFT; HUMORAL IMMUNITY; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ALLOANTIBODY; CD40 COSTIMULATION; MEMORY T CELLS;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD40; CD4-POSITIVE T-LYMPHOCYTES; CD40 LIGAND; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GRAFT REJECTION; GRAFT SURVIVAL; HEART TRANSPLANTATION; IMMUNITY, HUMORAL; IMMUNOLOGIC MEMORY; ISOANTIBODIES; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, INBRED DBA; TISSUE DONORS;

EID: 84886797075     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/ajt.12432     Document Type: Article

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