Enabling hyperpolarized 129Xe MR spectroscopy and imaging of pulmonary gas transfer to the red blood cells in transgenic mice expressing human hemoglobin

Magnetic Resonance in Medicine

Volumn 70, Issue 5, 2013, Pages 1192-1199

  Freeman, Matthew S ^a,b   Cleveland, Zackary I ^a   Qi, Yi ^a   Driehuys, Bastiaan ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b DUKE UNIVERSITY   (United States)

Author keywords

chemical shift saturation recovery; gas exchange; interstitial lung disease; mouse model; red blood cell

Indexed keywords

BIOLOGICAL ORGANS; CELLS; CHEMICAL SHIFT; DISSOLUTION; GASES; HEMOGLOBIN; HISTOLOGY; MAGNETIC RESONANCE SPECTROSCOPY; MAMMALS; MOLECULAR BIOLOGY; TISSUE;

DISEASE MODELS; GAS EXCHANGE; HYPERPOLARIZED; INTERSTITIAL LUNG DISEASE; MOUSE MODELS; MR SPECTROSCOPY; RED BLOOD CELL; TRANSGENIC MICE;

BLOOD;

HEMOGLOBIN; RADIOISOTOPE; UNCLASSIFIED DRUG; XENON 129;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ERYTHROCYTE; HYPERPOLARIZATION; IMAGING SYSTEM; LUNG GAS EXCHANGE; MAGNET; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN EXPRESSION;

CHEMICAL SHIFT SATURATION RECOVERY; GAS EXCHANGE; HYPERPOLARIZED 129XE; INTERSTITIAL LUNG DISEASE; MOUSE MODEL; RED BLOOD CELL;

ADMINISTRATION, INHALATION; ANIMALS; CELL TRACKING; CONTRAST MEDIA; ERYTHROCYTES; HEMOGLOBINS; HUMANS; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PULMONARY GAS EXCHANGE; RADIOPHARMACEUTICALS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TISSUE DISTRIBUTION; XENON ISOTOPES;

EID: 84886776253     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.24915     Document Type: Article

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