In vivo MR imaging and spectroscopy using hyperpolarized 129Xe

Magnetic Resonance in Medicine

Volumn 36, Issue 2, 1996, Pages 183-191

  Wagshul, Mark E ^a   Button, Terry M ^a   Li, Haifang F ^a   Liang, Zhengrong ^a   Springer, Charles S ^a   Zhong, Kai ^a   Wishnia, Arnold ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

bulk magnetic susceptibility; hyperpolarized 129Xe; in vivo 129Xe spectroscopy; MRI of lung

Indexed keywords

BIOLOGICAL ORGANS; GASES; MAGNETIC RESONANCE IMAGING; MAGNETIC SUSCEPTIBILITY;

BULK MAGNETIC SUSCEPTIBILITIES; COMPLEX STRUCTURE; FREQUENCY OSCILLATIONS; HYPERPOLARIZED; IN-VIVO; MAXIMUM INTENSITIES; TISSUE COMPONENTS; VASCULARIZED TISSUES;

TISSUE;

XENON;

ARTICLE; BLOOD; BREATHING; DIAGNOSTIC IMAGING; HYPERPOLARIZATION; LUNG; LUNG GAS EXCHANGE; LUNG PARENCHYMA; LUNG VOLUME; MAGNETISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

EID: 0029742918     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrm.1910360203     Document Type: Article

References (26)

1. W. Happer, E. Miron, S. Schaefer, D. Schreibor, W. A. Van Wijngaarden, X. Zeng, Polarization of the nuclear spins of noble-gas atoms by spin exchange with optically pumped alkali-metal atoms. Phys. Rev. A 29, 3092-3110 (1984).
2. D. Raftery, H. Long, T. Meersmann, P. J. Grandinetti, L. Reven, A. Pines, High-field NMR of adsorbed xenon polarized by laser pumping. Phys. Rev. Lett. 66, 584-587 (1991).
3. 129Xe. Nature 370, 199-201 (1994).
4. 3He gas. Magn. Reson. Med. 33, 271-275 (1995).
5. 129Xe magnetic resonance imaging and spectroscopy of the living mouse, in "Proc., SMR, 3rd Annual Meeting, Nice, France, 1995," p. 1194.
6. G. A. Johnson, R. D. Black, G. D. Cates, G. Cofer, R. Gunther, W. Happer, L. W. Hedlund, H. Middleton, J. Swartz, MRI using hyperpolarized gases, in "Proc., SMR, 3rd Annual Meeting, Nice, France, 1995," p. 392.
7. M. H. Abraham, M. J. Kalmet, R. W. Taft, R. M. Doherty, P. K. Weathersby, Solubility properties in polymers and biological media. J. Med. Chem. 28, 865-870 (1985).
8. 3He nucleus in liquid solvents and comparison with other noble gases. J. Magn. Reson. 101, 78-83 (1993).
9. S. Y. Yeh, R. E. Peterson, Solubility of carbon dioxide, krypton and xenon in lipids. J. Pharm. Sci. 52, 453-458 (1963).
10. K. Kitani, Solubility coefficients of krypton-85 and xenon-133 in water, saline, lipids, and blood. Scand. J. Clin. Lab. Invest. 29, 167-172 (1972).
11. R. A. Smith, E. G. Porter, K. W. Miller, The solubility of anesthetic gases in lipid bilayers. Biochim. Biophys. Acta 645, 327-338 (1981).
12. A. Wishnia, Substrate specificity at the alkane binding sites of hemoglobin and myoglobin. Biochemistry 8, 5064-5070 (1969).
13. K. W. Miller, N. V. Reo, A. J. Uiterkamp, D. P. Stengle, T. R. Stengle, K. L. Williamson, Xenon NMR: chemical shifts of a general anesthetic in common solvents, proteins, and membranes. Proc. Natl. Acad. Sci. 78, 4946-4949 (1981).
14. C. H. Durney, J. Bertolina, D. C. Ailion, R. Christman, A. G. Cutillo, A. H. Morris, S. Hashemi, Calculation and interpretation of inhomogeneous line broadening in models of lungs and other heterogeneous structures. J. Magn. Reson. 85, 554-570 (1989).
15. J. R. Mayo, A. MacKay, N. L. Muller, MR imaging of the lungs: value of short TE spin-echo pulse sequences Am. J. Radiol. 159, 951-956 (1992).
16. S. L. Gewalt, G. H. Glover, L. W. Hedlund, G. P. Cofer, J. R. MacFall, G. A. Johnson, MR microscopy of the rat lung using projection reconstruction. Magn. Reson. Med. 29, 99-106 (1993).
17. J. R. Mayo, W. R. Webb, R. Gould, M. G. Stein, I. Bass, G. Gamsu, H. I. Goldberg, High-resolution CT of the lungs: an optimal approach. Radiology 163, 507-510 (1987).
18. A. Alavi, Perfusion-ventilation lung scans in the diagnosis of pulmonary thromboembolism. Appl. Radiol. 6, 182-188 (1977).
19. PIOPED Investigators, Value of ventilation/perfusion scan in acute pulmonary embolism: results of the prospective investigation of pulmonary embolism diagnosis (PIOPED). JAMA 263, 2753-2759 (1990).
20. 2 and chemical shift imaging. Magn. Reson. Med. 13, 77-89 (1990).
21. C. S. Springer, Jr., Physicochemical principles influencing magnetopharmaceuticals, in "NMR in Physiology and Biomedicine" (R. J. Gillies, Ed.), pp. 75-99, Academic Press, San Diego, 1994.
22. S. C. K. Chu, Y. Xu, J. A. Balschi, C. S. Springer, Jr., Bulk magnetic susceptibility shifts in NMR studies of compartmentalized samples: use of paramagnetic reagents. Magn. Reson. Med. 13, 239-262 (1990).
23. D. C. Ailion, Potential industrial applications of inhomogeneous broadening imaging. Magn. Reson. Imaging 10, 799-808 (1992).
24. M. L. Crosfill, J. G. Widdicombe, Physical characteristics of the chest and lung and the work of breathing in different mammalian species. J. Physiol. (London) 158, 1-14 (1961).
25. 129Xe in oxygen. J. Chem. Phys. 89, 4074-4081 (1988).
26. 129Xe gas NMR spectroscopy and imaging with a whole-body imager. J. Magn. Reson. A108, 106-109 (1994).