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Volumn 98, Issue 4, 2013, Pages 437-445

WT1 mutation in pediatric patients with acute myeloid leukemia: A report from the Japanese Childhood AML Cooperative Study Group

(16)  Sano, Hirozumi a,g   Shimada, Akira a,b   Tabuchi, Ken c   Taki, Tomohiko d   Murata, Chisato a   Park, Myoung Ja a   Ohki, Kentaro a   Sotomatsu, Manabu a   Adachi, Souichi e   Tawa, Akio f   Kobayashi, Ryoji g   Horibe, Keizo h   Tsuchida, Masahiro i   Hanada, Ryoji j   Tsukimoto, Ichiro k   Hayashi, Yasuhide a  


Author keywords

Acute myeloid leukemia; Cytogenetically normal acute myeloid leukemia; Prognosis; WT1 mutation

Indexed keywords

ACUTE GRANULOCYTIC LEUKEMIA; ADOLESCENT; ARTICLE; CANCER INCIDENCE; CANCER PROGNOSIS; CHILD; CHILDHOOD LEUKEMIA; DISEASE FREE SURVIVAL; FEMALE; GENE MUTATION; HUMAN; JAPANESE; MAJOR CLINICAL STUDY; MALE; ONCOGENE; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PRESCHOOL CHILD; SCHOOL CHILD; WILMS TUMOR 1 GENE;

EID: 84886772237     PISSN: 09255710     EISSN: 18653774     Source Type: Journal    
DOI: 10.1007/s12185-013-1409-6     Document Type: Article
Times cited : (19)

References (37)
  • 1
    • 28544447722 scopus 로고    scopus 로고
    • Treatment strategy and long-term results in paediatric patients treated in consecutive UK AML trials
    • 16304572 10.1038/sj.leu.2403924 1:CAS:528:DC%2BD2MXht1ems7jJ
    • Gibson BE, Wheatley K, Hann IM, Stevens RF, Webb D, Hills RK, et al. Treatment strategy and long-term results in paediatric patients treated in consecutive UK AML trials. Leukemia. 2005;19:2130-8.
    • (2005) Leukemia , vol.19 , pp. 2130-2138
    • Gibson, B.E.1    Wheatley, K.2    Hann, I.M.3    Stevens, R.F.4    Webb, D.5    Hills, R.K.6
  • 2
    • 28544443076 scopus 로고    scopus 로고
    • Long term results in children with AML: NOPHO-AML Study Group - Report of three consecutive trials
    • 16304571 10.1038/sj.leu.2403962 1:CAS:528:DC%2BD2MXht1ems7nL
    • Lie SO, Abrahamsson J, Clausen N, Forestier E, Hasle H, Hovi L, et al. Long term results in children with AML: NOPHO-AML Study Group - report of three consecutive trials. Leukemia. 2005;19:2090-100.
    • (2005) Leukemia , vol.19 , pp. 2090-2100
    • Lie, S.O.1    Abrahamsson, J.2    Clausen, N.3    Forestier, E.4    Hasle, H.5    Hovi, L.6
  • 3
    • 33749041474 scopus 로고    scopus 로고
    • Less toxicity by optimizing chemotherapy, but not by addition of granulocyte colony-stimulating factor in children and adolescents with acute myeloid leukemia: Results of AML-BFM 98
    • 16983120 10.1200/JCO.2006.06.5037 1:CAS:528:DC%2BD28XhtVyisrrE
    • Creutzig U, Zimmermann M, Lehrnbecher T, Graf N, Hermann J, Niemeyer CM, et al. Less toxicity by optimizing chemotherapy, but not by addition of granulocyte colony-stimulating factor in children and adolescents with acute myeloid leukemia: results of AML-BFM 98. J Clin Oncol. 2006;24:4499-506.
    • (2006) J Clin Oncol , vol.24 , pp. 4499-4506
    • Creutzig, U.1    Zimmermann, M.2    Lehrnbecher, T.3    Graf, N.4    Hermann, J.5    Niemeyer, C.M.6
  • 4
    • 38949185746 scopus 로고    scopus 로고
    • Outcomes in CCG-2961, a children's oncology group phase 3 trial for untreated pediatric acute myeloid leukemia: A report from the children's oncology group
    • 18000167 10.1182/blood-2007-04-084293 1:CAS:528:DC%2BD1cXhvFejsb4%3D
    • Lange BJ, Smith FO, Feusner J, Barnard DR, Dinndorf P, Feig S, et al. Outcomes in CCG-2961, a children's oncology group phase 3 trial for untreated pediatric acute myeloid leukemia: a report from the children's oncology group. Blood. 2008;111:1044-53.
    • (2008) Blood , vol.111 , pp. 1044-1053
    • Lange, B.J.1    Smith, F.O.2    Feusner, J.3    Barnard, D.R.4    Dinndorf, P.5    Feig, S.6
  • 5
    • 69849101233 scopus 로고    scopus 로고
    • Risk-stratified therapy and the intensive use of cytarabine improves the outcome in childhood acute myeloid leukemia: The AML99 trial from the Japanese Childhood AML Cooperative Study Group
    • 19620491 10.1200/JCO.2008.18.7948 1:CAS:528:DC%2BD1MXhtFCgsbvP
    • Tsukimoto I, Tawa A, Horibe K, Tabuchi K, Kigasawa H, Tsuchida M, et al. Risk-stratified therapy and the intensive use of cytarabine improves the outcome in childhood acute myeloid leukemia: The AML99 trial from the Japanese Childhood AML Cooperative Study Group. J Clin Oncol. 2009;27:4007-13.
    • (2009) J Clin Oncol , vol.27 , pp. 4007-4013
    • Tsukimoto, I.1    Tawa, A.2    Horibe, K.3    Tabuchi, K.4    Kigasawa, H.5    Tsuchida, M.6
  • 6
    • 77953483479 scopus 로고    scopus 로고
    • Minimal residual disease-directed therapy for childhood acute myeloid leukaemia: Results of the AML 02 multicentre trial
    • 20451454 10.1016/S1470-2045(10)70090-5 1:CAS:528:DC%2BC3cXntVCksbs%3D
    • Rubnitz JE, Inaba H, Dahl G, Ribeiro RC, Bowman WP, Taub J, et al. Minimal residual disease-directed therapy for childhood acute myeloid leukaemia: results of the AML 02 multicentre trial. Lancet Oncol. 2010;11:543-52.
    • (2010) Lancet Oncol , vol.11 , pp. 543-552
    • Rubnitz, J.E.1    Inaba, H.2    Dahl, G.3    Ribeiro, R.C.4    Bowman, W.P.5    Taub, J.6
  • 7
    • 0032188805 scopus 로고    scopus 로고
    • The importance of diagnostic cytogenetics on outcome of AML: Analysis of 1612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties
    • 9746770 1:CAS:528:DyaK1cXmsVKnsrw%3D
    • Grimwade D, Walker H, Oliver F, Wheatley K, Harrison C, Harrison G, et al. The importance of diagnostic cytogenetics on outcome of AML: analysis of 1612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties. Blood. 1998;92:2322-33.
    • (1998) Blood , vol.92 , pp. 2322-2333
    • Grimwade, D.1    Walker, H.2    Oliver, F.3    Wheatley, K.4    Harrison, C.5    Harrison, G.6
  • 8
    • 33846230449 scopus 로고    scopus 로고
    • Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: Are we ready for a prognostically prioritized molecular classification?
    • 16960150 10.1182/blood-2006-06-001149
    • Mrózek K, Marcucci G, Paschka P, Whitman SP, Bloomfield CD. Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classification? Blood. 2007;109:431-48.
    • (2007) Blood , vol.109 , pp. 431-448
    • Mrózek, K.1    Marcucci, G.2    Paschka, P.3    Whitman, S.P.4    Bloomfield, C.D.5
  • 9
    • 34548234969 scopus 로고    scopus 로고
    • High expression levels of the ETS-related gene, ERG, predict adverse outcome and improve molecular risk-based classification of cytogenetically normal acute myeloid leukemia: A Cancer and Leukemia Group B Study
    • 17577018 10.1200/JCO.2007.10.8720 1:CAS:528:DC%2BD2sXhtVWqs7jJ
    • Marcucci G, Maharry K, Whitman SP, Vukosavljevic T, Paschka P, Langer C, et al. High expression levels of the ETS-related gene, ERG, predict adverse outcome and improve molecular risk-based classification of cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B Study. J Clin Oncol. 2007;25:3337-43.
    • (2007) J Clin Oncol , vol.25 , pp. 3337-3343
    • Marcucci, G.1    Maharry, K.2    Whitman, S.P.3    Vukosavljevic, T.4    Paschka, P.5    Langer, C.6
  • 10
    • 0025099787 scopus 로고
    • Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus
    • 2154335 10.1016/0092-8674(90)90601-A 1:CAS:528:DyaK3cXhtlelt7Y%3D
    • Call KM, Glaser T, Ito CY, Buckler AJ, Pelletier J, Haber DA, et al. Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus. Cell. 1990;60:509-20.
    • (1990) Cell , vol.60 , pp. 509-520
    • Call, K.M.1    Glaser, T.2    Ito, C.Y.3    Buckler, A.J.4    Pelletier, J.5    Haber, D.A.6
  • 11
    • 34247579714 scopus 로고    scopus 로고
    • A tumor suppressor and oncogene: The WT1 story
    • 17361230 1:CAS:528:DC%2BD2sXksFeltbo%3D
    • Yang L, Han Y, Suarez Saiz F, Minden MD. A tumor suppressor and oncogene: the WT1 story. Leukemia. 2007;21:868-76.
    • (2007) Leukemia , vol.21 , pp. 868-876
    • Yang, L.1    Han, Y.2    Suarez Saiz, F.3    Minden, M.D.4
  • 12
    • 0025288793 scopus 로고
    • An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor
    • 2163761 10.1016/0092-8674(90)90690-G 1:CAS:528:DyaK3cXltFSgsLo%3D
    • Haber DA, Buckler AJ, Glaser T, Call KM, Pelletier J, Sohn RL, et al. An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor. Cell. 1990;61:1257-69.
    • (1990) Cell , vol.61 , pp. 1257-1269
    • Haber, D.A.1    Buckler, A.J.2    Glaser, T.3    Call, K.M.4    Pelletier, J.5    Sohn, R.L.6
  • 13
    • 34250784012 scopus 로고    scopus 로고
    • The role of the Wilms tumour gene (WT1) in normal and malignant haematopoiesis
    • 17524167 10.1017/S1462399407000336
    • Ariyaratana S, Loeb DM. The role of the Wilms tumour gene (WT1) in normal and malignant haematopoiesis. Expert Rev Mol Med. 2007;9:1-17.
    • (2007) Expert Rev Mol Med , vol.9 , pp. 1-17
    • Ariyaratana, S.1    Loeb, D.M.2
  • 14
    • 9244237089 scopus 로고    scopus 로고
    • Growth inhibition of human leukemic cells by WT1 (Wilms tumor gene) antisense oligodeoxynucleotides: Implications for the involvement of WT1 in leukemogenesis
    • 8639907 1:CAS:528:DyaK28XhvFeltLc%3D
    • Yamagami T, Sugiyama H, Inoue K, Ogawa H, Tatekawa T, Hirata M, et al. Growth inhibition of human leukemic cells by WT1 (Wilms tumor gene) antisense oligodeoxynucleotides: implications for the involvement of WT1 in leukemogenesis. Blood. 1996;87:2878-84.
    • (1996) Blood , vol.87 , pp. 2878-2884
    • Yamagami, T.1    Sugiyama, H.2    Inoue, K.3    Ogawa, H.4    Tatekawa, T.5    Hirata, M.6
  • 15
    • 33645729159 scopus 로고    scopus 로고
    • AML1-ETO rapidly induces acute myeloblastic leukemia in cooperation with the Wilms tumor gene, WT1
    • 16380455 10.1182/blood-2005-04-1656 1:CAS:528:DC%2BD28Xjs1Oks7c%3D
    • Nishida S, Hosen N, Shirakata T, Kanato K, Yanagihara M, Nakatsuka S, et al. AML1-ETO rapidly induces acute myeloblastic leukemia in cooperation with the Wilms tumor gene, WT1. Blood. 2006;107:3303-12.
    • (2006) Blood , vol.107 , pp. 3303-3312
    • Nishida, S.1    Hosen, N.2    Shirakata, T.3    Kanato, K.4    Yanagihara, M.5    Nakatsuka, S.6
  • 16
    • 53749101166 scopus 로고    scopus 로고
    • Wilms' tumor 1 gene mutations independently predict poor outcome in adults with cytogenetically normal acute myeloid leukemia: A cancer and leukemia group B study
    • 18559874 10.1200/JCO.2007.15.2058 1:CAS:528:DC%2BD1cXht1KqtLfJ
    • Paschka P, Marcucci G, Ruppert AS, Whitman SP, Mrozek K, Maharry K, et al. Wilms' tumor 1 gene mutations independently predict poor outcome in adults with cytogenetically normal acute myeloid leukemia: a cancer and leukemia group B study. J Clin Oncol. 2008;26:4595-602.
    • (2008) J Clin Oncol , vol.26 , pp. 4595-4602
    • Paschka, P.1    Marcucci, G.2    Ruppert, A.S.3    Whitman, S.P.4    Mrozek, K.5    Maharry, K.6
  • 17
    • 56749098118 scopus 로고    scopus 로고
    • Mutation of the Wilms' tumor 1 gene is a poor prognostic factor associated with chemotherapy resistance in normal karyotype acute myeloid leukemia: The United Kingdom Medical Research Council Adult Leukaemia Working Party
    • 18591546 10.1200/JCO.2008.16.0333 1:CAS:528:DC%2BD1MXhslClsQ%3D%3D
    • Virappane P, Gale R, Hills R, Kakkas I, Summers K, Stevens J, et al. Mutation of the Wilms' tumor 1 gene is a poor prognostic factor associated with chemotherapy resistance in normal karyotype acute myeloid leukemia: the United Kingdom Medical Research Council Adult Leukaemia Working Party. J Clin Oncol. 2008;26:5429-35.
    • (2008) J Clin Oncol , vol.26 , pp. 5429-5435
    • Virappane, P.1    Gale, R.2    Hills, R.3    Kakkas, I.4    Summers, K.5    Stevens, J.6
  • 18
    • 66549116716 scopus 로고    scopus 로고
    • Prognostic impact of WT1 mutations in cytogenetically normal acute myeloid leukemia: A study of the German-Austrian AML Study Group
    • 19221039 10.1182/blood-2008-10-183392 1:CAS:528:DC%2BD1MXnvVyqtLc%3D
    • Gaidzik VI, Schlenk RF, Moschny S, Becker A, Bullinger L, Corbacioglu A, et al. Prognostic impact of WT1 mutations in cytogenetically normal acute myeloid leukemia: a study of the German-Austrian AML Study Group. Blood. 2009;113:4505-11.
    • (2009) Blood , vol.113 , pp. 4505-4511
    • Gaidzik, V.I.1    Schlenk, R.F.2    Moschny, S.3    Becker, A.4    Bullinger, L.5    Corbacioglu, A.6
  • 19
  • 20
    • 33847238455 scopus 로고    scopus 로고
    • Wilms' tumour 1 mutations are associated with FLT3-ITD and failure of standard induction chemotherapy in patients with normal karyotype AML
    • 17205055 10.1038/sj.leu.2404514 1:CAS:528:DC%2BD2sXhvFWksLg%3D
    • Summers K, Stevens J, Kakkas I, Smith M, Smith LL, Macdougall F, et al. Wilms' tumour 1 mutations are associated with FLT3-ITD and failure of standard induction chemotherapy in patients with normal karyotype AML. Leukemia. 2007;21:550-1.
    • (2007) Leukemia , vol.21 , pp. 550-551
    • Summers, K.1    Stevens, J.2    Kakkas, I.3    Smith, M.4    Smith, L.L.5    Macdougall, F.6
  • 21
    • 77956275074 scopus 로고    scopus 로고
    • Prevalence and prognostic implications of WT1 mutations in pediatric acute myeloid leukemia (AML): A report from the Children's Oncology Group
    • 20413658 10.1182/blood-2010-02-268953 1:CAS:528:DC%2BC3cXhtVCku7zN
    • Ho PA, Zeng R, Alonzo TA, Gerbing RB, Miller KL, Pollard JA, et al. Prevalence and prognostic implications of WT1 mutations in pediatric acute myeloid leukemia (AML): a report from the Children's Oncology Group. Blood. 2010;116:702-10.
    • (2010) Blood , vol.116 , pp. 702-710
    • Ho, P.A.1    Zeng, R.2    Alonzo, T.A.3    Gerbing, R.B.4    Miller, K.L.5    Pollard, J.A.6
  • 22
    • 82155183329 scopus 로고    scopus 로고
    • Presence of FLT3-ITD and high BAALC expression are independent prognostic markers in childhood acute myeloid leukemia
    • 21967978 10.1182/blood-2011-05-353185 1:CAS:528:DC%2BC3MXhs1ShtrbK
    • Staffas A, Kanduri M, Hovland R, Rosenquist R, Ommen HB, Abrahamsson J, et al. Presence of FLT3-ITD and high BAALC expression are independent prognostic markers in childhood acute myeloid leukemia. Blood. 2011;118:5905-13.
    • (2011) Blood , vol.118 , pp. 5905-5913
    • Staffas, A.1    Kanduri, M.2    Hovland, R.3    Rosenquist, R.4    Ommen, H.B.5    Abrahamsson, J.6
  • 23
    • 33344471932 scopus 로고    scopus 로고
    • KIT mutations, and not FLT3 internal tandem duplication, are strongly associated with a poor prognosis in pediatric acute myeloid leukemia with t(8;21): A study of the Japanese Childhood AML Cooperative Study Group
    • 16291592 10.1182/blood-2005-08-3408 1:CAS:528:DC%2BD28XitFyht7c%3D
    • Shimada A, Taki T, Tabuchi K, Tawa A, Horibe K, Tsuchida M, et al. KIT mutations, and not FLT3 internal tandem duplication, are strongly associated with a poor prognosis in pediatric acute myeloid leukemia with t(8;21): A study of the Japanese Childhood AML Cooperative Study Group. Blood. 2006;107:1806-9.
    • (2006) Blood , vol.107 , pp. 1806-1809
    • Shimada, A.1    Taki, T.2    Tabuchi, K.3    Tawa, A.4    Horibe, K.5    Tsuchida, M.6
  • 24
    • 33847379392 scopus 로고    scopus 로고
    • Extramedullary infiltration at diagnosis and prognosis in children with acute myeloid leukemia
    • 16550530 10.1002/pbc.20824
    • Kobayashi R, Tawa A, Hanada R, Horibe K, Tsuchida M, Tsukimoto I. Extramedullary infiltration at diagnosis and prognosis in children with acute myeloid leukemia. Pediatr Blood Cancer. 2007;48:393-8.
    • (2007) Pediatr Blood Cancer , vol.48 , pp. 393-398
    • Kobayashi, R.1    Tawa, A.2    Hanada, R.3    Horibe, K.4    Tsuchida, M.5    Tsukimoto, I.6
  • 25
    • 37549071079 scopus 로고    scopus 로고
    • Tandem duplications of MLL and FLT3 are correlated with poor prognoses in pediatric acute myeloid leukemia: A study of the Japanese Childhood AML Cooperative Study Group
    • 17763464 10.1002/pbc.21318
    • Shimada A, Taki T, Tabuchi K, Taketani T, Hanada R, Tawa A, et al. Tandem duplications of MLL and FLT3 are correlated with poor prognoses in pediatric acute myeloid leukemia: a study of the Japanese Childhood AML Cooperative Study Group. Pediatr Blood Cancer. 2008;50:264-9.
    • (2008) Pediatr Blood Cancer , vol.50 , pp. 264-269
    • Shimada, A.1    Taki, T.2    Tabuchi, K.3    Taketani, T.4    Hanada, R.5    Tawa, A.6
  • 26
    • 0001097136 scopus 로고    scopus 로고
    • Tandem duplication of the FLT3 gene is found in acute lymphoblastic leukaemia as well as acute myeloid leukaemia but not in myelodysplastic syndrome or juvenile chronic myelogenous leukaemia in children
    • 10233379 10.1111/j.1365-2141.1999.01284.x 1:CAS:528:DyaK1MXivFSlt7o%3D
    • Xu F, Taki T, Yang HW, Hanada R, Hongo T, Ohnishi H, et al. Tandem duplication of the FLT3 gene is found in acute lymphoblastic leukaemia as well as acute myeloid leukaemia but not in myelodysplastic syndrome or juvenile chronic myelogenous leukaemia in children. Br J Haematol. 1999;105:155-62.
    • (1999) Br J Haematol , vol.105 , pp. 155-162
    • Xu, F.1    Taki, T.2    Yang, H.W.3    Hanada, R.4    Hongo, T.5    Ohnishi, H.6
  • 27
    • 9144244169 scopus 로고    scopus 로고
    • FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy
    • 14504097 10.1182/blood-2003-02-0418 1:CAS:528:DC%2BD2cXhtVaksL8%3D
    • Taketani T, Taki T, Sugita K, Furuichi Y, Ishii E, Hanada R, et al. FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy. Blood. 2004;103:1085-8.
    • (2004) Blood , vol.103 , pp. 1085-1088
    • Taketani, T.1    Taki, T.2    Sugita, K.3    Furuichi, Y.4    Ishii, E.5    Hanada, R.6
  • 28
    • 84862864582 scopus 로고    scopus 로고
    • RAS mutations are frequent in FAB type M4 and M5 of acute myeloid leukemia, and related to late relapse: A study of the Japanese Childhood AML Cooperative Study Group
    • 22407852 10.1007/s12185-012-1033-x
    • Sano H, Shimada A, Taki T, Murata C, Park MJ, Sotomatsu M, et al. RAS mutations are frequent in FAB type M4 and M5 of acute myeloid leukemia, and related to late relapse: a study of the Japanese Childhood AML Cooperative Study Group. Int J Hematol. 2012;95:509-15.
    • (2012) Int J Hematol , vol.95 , pp. 509-515
    • Sano, H.1    Shimada, A.2    Taki, T.3    Murata, C.4    Park, M.J.5    Sotomatsu, M.6
  • 29
    • 84868096615 scopus 로고    scopus 로고
    • High WT1 mRNA expression after induction chemotherapy and FLT3-ITD have prognostic impact in pediatric acute myeloid leukemia: A study of the Japanese Childhood AML Cooperative Study Group
    • 22915059 10.1007/s12185-012-1163-1 1:CAS:528:DC%2BC38XhsFamtbbN
    • Shimada A, Taki T, Koga D, Tabuchi K, Tawa A, Hanada R, et al. High WT1 mRNA expression after induction chemotherapy and FLT3-ITD have prognostic impact in pediatric acute myeloid leukemia: a study of the Japanese Childhood AML Cooperative Study Group. Int J Hematol. 2012;96:469-76.
    • (2012) Int J Hematol , vol.96 , pp. 469-476
    • Shimada, A.1    Taki, T.2    Koga, D.3    Tabuchi, K.4    Tawa, A.5    Hanada, R.6
  • 30
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observations
    • 10.1080/01621459.1958.10501452
    • Kaplan E, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc. 1957;53:457-81.
    • (1957) J Am Stat Assoc , vol.53 , pp. 457-481
    • Kaplan, E.1    Meier, P.2
  • 31
    • 0028121279 scopus 로고
    • A cell cycle regulator potentially involved in genesis of many tumor types
    • 8153634 10.1126/science.8153634 1:CAS:528:DyaK2cXktVKhtb0%3D
    • Kamb A, Gruis NA, Weaver-Feldhaus J, Liu Q, Harshman K, Tavtigian SV, et al. A cell cycle regulator potentially involved in genesis of many tumor types. Science. 1994;264:436-40.
    • (1994) Science , vol.264 , pp. 436-440
    • Kamb, A.1    Gruis, N.A.2    Weaver-Feldhaus, J.3    Liu, Q.4    Harshman, K.5    Tavtigian, S.V.6
  • 32
    • 0028275733 scopus 로고
    • Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
    • 8152487 10.1038/368753a0 1:STN:280:DyaK2c3gtlarug%3D%3D
    • Nobori T, Miura K, Wu DJ, Lois A, Takabayashi K, Carson DA. Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature. 1994;368:753-6.
    • (1994) Nature , vol.368 , pp. 753-756
    • Nobori, T.1    Miura, K.2    Wu, D.J.3    Lois, A.4    Takabayashi, K.5    Carson, D.A.6
  • 34
    • 44049086446 scopus 로고    scopus 로고
    • Cooperating gene mutations in acute myeloid leukemia: A review of the literature
    • 18288131 10.1038/leu.2008.19 1:CAS:528:DC%2BD1cXlvVSrsLY%3D
    • Renneville A, Roumier C, Biggio V, Nibourel O, Boissel N, Fenaux P, et al. Cooperating gene mutations in acute myeloid leukemia: a review of the literature. Leukemia. 2008;22:915-31.
    • (2008) Leukemia , vol.22 , pp. 915-931
    • Renneville, A.1    Roumier, C.2    Biggio, V.3    Nibourel, O.4    Boissel, N.5    Fenaux, P.6
  • 35
    • 68749092656 scopus 로고    scopus 로고
    • Standardization of WT1 mRNA quantitation for minimal residual disease monitoring in childhood AML and implications of WT1 gene mutations: A European multicenter study
    • 19322206 10.1038/leu.2009.51 1:CAS:528:DC%2BD1MXpvF2kur8%3D
    • Willasch AM, Gruhn B, Coliva T, Kalinova M, Schneider G, Kreyenberg H, et al. Standardization of WT1 mRNA quantitation for minimal residual disease monitoring in childhood AML and implications of WT1 gene mutations: a European multicenter study. Leukemia. 2009;23:1472-9.
    • (2009) Leukemia , vol.23 , pp. 1472-1479
    • Willasch, A.M.1    Gruhn, B.2    Coliva, T.3    Kalinova, M.4    Schneider, G.5    Kreyenberg, H.6
  • 36
    • 2942597447 scopus 로고    scopus 로고
    • WT1 gene expression: An excellent tool for monitoring minimal residual disease in 70% of acute myeloid leukaemia patients - Results from a single-centre study
    • 15147374 10.1111/j.1365-2141.2004.04952.x
    • Østergaard M, Olesen LH, Hasle H, Kjeldsen E, Hokland P. WT1 gene expression: an excellent tool for monitoring minimal residual disease in 70% of acute myeloid leukaemia patients - results from a single-centre study. Br J Haematol. 2004;125:590-600.
    • (2004) Br J Haematol , vol.125 , pp. 590-600
    • Østergaard, M.1    Olesen, L.H.2    Hasle, H.3    Kjeldsen, E.4    Hokland, P.5
  • 37
    • 71049194464 scopus 로고    scopus 로고
    • WT1 expression at diagnosis does not predict survival in pediatric AML: A report from the Children's Oncology Group
    • 19618455 10.1002/pbc.22142
    • Noronha SA, Farrar JE, Alonzo TA, Gerbing RB, Lacayo NJ, Dahl GV, et al. WT1 expression at diagnosis does not predict survival in pediatric AML: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2009;53:1136-9.
    • (2009) Pediatr Blood Cancer , vol.53 , pp. 1136-1139
    • Noronha, S.A.1    Farrar, J.E.2    Alonzo, T.A.3    Gerbing, R.B.4    Lacayo, N.J.5    Dahl, G.V.6


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