Absence of genotoxic effects of the coumarin derivative 4-methylesculetin in vivo and its potential chemoprevention against doxorubicin-induced DNA damage

Journal of Applied Toxicology

Volumn 34, Issue 1, 2014, Pages 33-39

  Fedato, Rafael Palhano ^a   Maistro, Edson Luis ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

4 methylesculetin; Antigenotoxic effects; Comet assay; Coumarin derivative; Micronucleus test

Indexed keywords

4 METHYLESCULETIN; COUMARIN DERIVATIVE; DOXORUBICIN; ONCODOX; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; DRUG CYTOTOXICITY; ERYTHROCYTE; GENOTOXICITY; IN VIVO STUDY; MALE; MICRONUCLEUS TEST; MOUSE; NONHUMAN; PRIORITY JOURNAL; RISK REDUCTION;

4-METHYLESCULETIN; ANTIGENOTOXIC EFFECTS; COMET ASSAY; COUMARIN DERIVATIVE; MICRONUCLEUS TEST;

ANIMALS; BONE MARROW CELLS; BRAIN; COMET ASSAY; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; DRUG EVALUATION, PRECLINICAL; ERYTHROCYTES; INJECTIONS, INTRAPERITONEAL; LIVER; MALE; MICE; MICRONUCLEUS TESTS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; TESTIS; UMBELLIFERONES;

EID: 84886769562     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.2823     Document Type: Article

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