메뉴 건너뛰기




Volumn 23, Issue 1, 2007, Pages 49-62

In vitro modeling of the structure-activity determinants of anthracycline cardiotoxicity

Author keywords

Anthracyclines; Cardiotoxicity; Structure activity determinants

Indexed keywords

ALPHA TOCOPHEROL; AMIFOSTINE; ANTHRACYCLINE; ANTIOXIDANT; ASCORBIC ACID; BMS 184476; BMS 310705; CHELATING AGENT; DAUNORUBICINOL; DOCETAXEL; DOXORUBICIN; DOXORUBICINOL; EPIRUBICIN; EPIRUBICINOL; EPOTHILONE B; IDARUBICIN; IXABEPILONE; MACROLIDE; MEN 11951; NITROXIDE DERIVATIVE; PACLITAXEL; PIPERIDINE DERIVATIVE; PROBUCOL; RAZOXANE; RETINOL; SABARUBICIN; SEMIQUINONE; TAXANE DERIVATIVE; TRASTUZUMAB; UNINDEXED DRUG;

EID: 33845670911     PISSN: 07422091     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10565-006-0143-8     Document Type: Conference Paper
Times cited : (40)

References (72)
  • 1
    • 0032543207 scopus 로고    scopus 로고
    • Defective acidification in human breast tumor cells and implications for chemotherapy
    • Altan N, Chen Y, Schindler M, Simon SM. Defective acidification in human breast tumor cells and implications for chemotherapy. J Exp Med. 1998;187:1583-98.
    • (1998) J Exp Med , vol.187 , pp. 1583-1598
    • Altan, N.1    Chen, Y.2    Schindler, M.3    Simon, S.M.4
  • 2
    • 0028853576 scopus 로고
    • Idarubicin cardiotoxicity: A retrospective study in acute myeloid leukemia and myelodysplasia
    • Anderlini P, Benjamin RS, Wong FC, et al. Idarubicin cardiotoxicity: a retrospective study in acute myeloid leukemia and myelodysplasia. J Clin Oncol. 1995;13:2827-34.
    • (1995) J Clin Oncol , vol.13 , pp. 2827-2834
    • Anderlini, P.1    Benjamin, R.S.2    Wong, F.C.3
  • 3
    • 0030807646 scopus 로고    scopus 로고
    • Doxorubicin disaccharide analogue: Apoptosis-related improvement of efficacy in vivo
    • Arcamone F, Animati F, Berettoni M, et al. Doxorubicin disaccharide analogue: apoptosis-related improvement of efficacy in vivo. J Natl Cancer Inst. 1997;89:1217-23.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 1217-1223
    • Arcamone, F.1    Animati, F.2    Berettoni, M.3
  • 5
    • 0033988708 scopus 로고    scopus 로고
    • Development of daunorubicin resistance in tumor cells by induction of carbonyl reduction
    • Ax W, Soldan M, Koch L, Maser E. Development of daunorubicin resistance in tumor cells by induction of carbonyl reduction. Biochem Pharmacol. 2000;59:293-300.
    • (2000) Biochem Pharmacol , vol.59 , pp. 293-300
    • Ax, W.1    Soldan, M.2    Koch, L.3    Maser, E.4
  • 6
    • 0027181002 scopus 로고
    • Drugs ten years later: Epirubicin
    • Bonadonna G, Gianni L, Santoro A, et al. Drugs ten years later: epirubicin. Ann Oncol. 1993;4:359-69.
    • (1993) Ann Oncol , vol.4 , pp. 359-369
    • Bonadonna, G.1    Gianni, L.2    Santoro, A.3
  • 8
    • 20844456403 scopus 로고    scopus 로고
    • A phase II study of sabarubicin (MEN-10755) as second line therapy in patients with locally advanced or metastatic platinum/taxane resistant ovarian cancer
    • Caponigro F, Willemse P, Sorio R, et al. A phase II study of sabarubicin (MEN-10755) as second line therapy in patients with locally advanced or metastatic platinum/taxane resistant ovarian cancer. Invest New Drugs. 2005;23:85-9.
    • (2005) Invest New Drugs , vol.23 , pp. 85-89
    • Caponigro, F.1    Willemse, P.2    Sorio, R.3
  • 9
    • 20944438956 scopus 로고    scopus 로고
    • Investigations of calsequestrin as a target for anthracyclines: Comparison of functional effects of daunorubicin, daunorubicinol, and trifluoperazine
    • Charlier HA Jr, Olson RD, Thornock CM, et al. Investigations of calsequestrin as a target for anthracyclines: comparison of functional effects of daunorubicin, daunorubicinol, and trifluoperazine. Mol Pharmacol. 2005;67:1505-12.
    • (2005) Mol Pharmacol , vol.67 , pp. 1505-1512
    • Charlier Jr., H.A.1    Olson, R.D.2    Thornock, C.M.3
  • 11
    • 0023938593 scopus 로고
    • Cytofluorescence localization and disposition of doxorubicin and doxorubicinol in rat cardiac tissue
    • Danesi R, Paparelli A, Bernardini N, Del Tacca M. Cytofluorescence localization and disposition of doxorubicin and doxorubicinol in rat cardiac tissue. Eur J Cancer Clin Oncol. 1988; 24:1123-31.
    • (1988) Eur J Cancer Clin Oncol , vol.24 , pp. 1123-1131
    • Danesi, R.1    Paparelli, A.2    Bernardini, N.3    Del Tacca, M.4
  • 12
    • 0036310616 scopus 로고    scopus 로고
    • Pharmacokinetic-pharmacodynamic relationships of the anthracycline anticancer drugs
    • Danesi R, Fogli S, Gennari A, Conte P, Del Tacca M. Pharmacokinetic- pharmacodynamic relationships of the anthracycline anticancer drugs. Clin Pharmacokinet. 2002;41:431-44.
    • (2002) Clin Pharmacokinet , vol.41 , pp. 431-444
    • Danesi, R.1    Fogli, S.2    Gennari, A.3    Conte, P.4    Del Tacca, M.5
  • 13
    • 0031647550 scopus 로고    scopus 로고
    • Taxoids in combination with anthracyclines and other agents: Pharmacokinetic considerations
    • D'Incalci M, Schuller J, Colombo T, Zucchetti M, Riva A. Taxoids in combination with anthracyclines and other agents: pharmacokinetic considerations. Semin Oncol. 1998;25:16-20.
    • (1998) Semin Oncol , vol.25 , pp. 16-20
    • D'Incalci, M.1    Schuller, J.2    Colombo, T.3    Zucchetti, M.4    Riva, A.5
  • 14
    • 30544432353 scopus 로고    scopus 로고
    • EORTC new drug development group. A study from the EORTC new drug development group: Open label phase II study of sabarubicin (MEN-10755) in patients with progressive hormone refractory prostate cancer
    • Fiedler W, Tchen N, Bloch J, et al., EORTC new drug development group. A study from the EORTC new drug development group: open label phase II study of sabarubicin (MEN-10755) in patients with progressive hormone refractory prostate cancer. Eur J Cancer. 2006;42:200-4.
    • (2006) Eur J Cancer , vol.42 , pp. 200-204
    • Fiedler, W.1    Tchen, N.2    Bloch, J.3
  • 15
    • 0034047105 scopus 로고    scopus 로고
    • Effects of protein binding on the in vitro activity of antitumour acridine derivatives and related anticancer drugs
    • Finlay GJ, Baguley BC. Effects of protein binding on the in vitro activity of antitumour acridine derivatives and related anticancer drugs. Cancer Chemother Pharmacol. 2000;45:417-22.
    • (2000) Cancer Chemother Pharmacol , vol.45 , pp. 417-422
    • Finlay, G.J.1    Baguley, B.C.2
  • 16
    • 0034665414 scopus 로고    scopus 로고
    • Human carbonyl reductase overexpression in the heart advances the development of doxorubicin-induced cardiotoxicity in transgenic mice
    • Forrest GL, Gonzalez B, Tseng W, Li X, Mann J. Human carbonyl reductase overexpression in the heart advances the development of doxorubicin-induced cardiotoxicity in transgenic mice. Cancer Res. 2000;60:5158-64.
    • (2000) Cancer Res , vol.60 , pp. 5158-5164
    • Forrest, G.L.1    Gonzalez, B.2    Tseng, W.3    Li, X.4    Mann, J.5
  • 17
    • 0036293197 scopus 로고    scopus 로고
    • Doxorubicin and C-13 deoxydoxorubicin effects on ryanodine receptor gene expression
    • Gambliel HA, Burke BE, Cusack BJ, et al. Doxorubicin and C-13 deoxydoxorubicin effects on ryanodine receptor gene expression. Biochem Biophys Res Commun. 2002;291:433-8.
    • (2002) Biochem Biophys Res Commun , vol.291 , pp. 433-438
    • Gambliel, H.A.1    Burke, B.E.2    Cusack, B.J.3
  • 18
    • 0033006172 scopus 로고    scopus 로고
    • A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin
    • Gewirtz DA. A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. Biochem Pharmacol. 1999;57:727-41.
    • (1999) Biochem Pharmacol , vol.57 , pp. 727-741
    • Gewirtz, D.A.1
  • 19
    • 0028877036 scopus 로고
    • Paclitaxel by 3-hour infusion in combination with bolus doxorubicin in women with untreated metastatic breast cancer: High antitumor efficacy and cardiac effects in a dose-finding and sequence-finding study
    • Gianni L, Munzone E, Capri G, et al. Paclitaxel by 3-hour infusion in combination with bolus doxorubicin in women with untreated metastatic breast cancer: high antitumor efficacy and cardiac effects in a dose-finding and sequence-finding study. J Clin Oncol. 1995;13:2688-99.
    • (1995) J Clin Oncol , vol.13 , pp. 2688-2699
    • Gianni, L.1    Munzone, E.2    Capri, G.3
  • 20
    • 0030977999 scopus 로고    scopus 로고
    • Human pharmacokinetic characterization and in vitro study of the interaction between doxorubicin and paclitaxel in patients with breast cancer
    • Gianni L, Vigano L, Locatelli A, et al. Human pharmacokinetic characterization and in vitro study of the interaction between doxorubicin and paclitaxel in patients with breast cancer. J Clin Oncol. 1997;15:1906-15.
    • (1997) J Clin Oncol , vol.15 , pp. 1906-1915
    • Gianni, L.1    Vigano, L.2    Locatelli, A.3
  • 21
    • 29344467956 scopus 로고    scopus 로고
    • Feasibility and tolerability of sequential doxorubicin/paclitaxel followed by cyclophosphamide, methotrexate, and fluorouracil and its effects on tumor response as preoperative therapy
    • Gianni L, Baselga J, Eiermann W, et al. Feasibility and tolerability of sequential doxorubicin/paclitaxel followed by cyclophosphamide, methotrexate, and fluorouracil and its effects on tumor response as preoperative therapy. Clin Cancer Res. 2005;11:8715-21.
    • (2005) Clin Cancer Res , vol.11 , pp. 8715-8721
    • Gianni, L.1    Baselga, J.2    Eiermann, W.3
  • 22
    • 21644470216 scopus 로고    scopus 로고
    • Expressional reprogramming of survival pathways in rat cardiocytes by neuregulin-1beta
    • Giraud MN, Fluck M, Zuppinger C, Suter TM. Expressional reprogramming of survival pathways in rat cardiocytes by neuregulin-1beta. J Appl Physiol. 2005;99:313-22.
    • (2005) J Appl Physiol , vol.99 , pp. 313-322
    • Giraud, M.N.1    Fluck, M.2    Zuppinger, C.3    Suter, T.M.4
  • 23
    • 0028843727 scopus 로고
    • Protection against daunorubicin cytotoxicity by expression of a cloned human carbonyl reductase cDNA in K562 leukemia cells
    • Gonzalez B, Akman S, Doroshow J, Rivera H, Kaplan WD, Forrest GL. Protection against daunorubicin cytotoxicity by expression of a cloned human carbonyl reductase cDNA in K562 leukemia cells. Cancer Res. 1995;55:4646-50.
    • (1995) Cancer Res , vol.55 , pp. 4646-4650
    • Gonzalez, B.1    Akman, S.2    Doroshow, J.3    Rivera, H.4    Kaplan, W.D.5    Forrest, G.L.6
  • 24
    • 0035126141 scopus 로고    scopus 로고
    • Tissue distribution, antitumour activity and in vivo apoptosis induction by MEN10755 in nude mice
    • Gonzalez-Paz O, Polizzi D, De Cesare M, et al. Tissue distribution, antitumour activity and in vivo apoptosis induction by MEN10755 in nude mice. Eur J Cancer. 2001;37:431-7.
    • (2001) Eur J Cancer , vol.37 , pp. 431-437
    • Gonzalez-Paz, O.1    Polizzi, D.2    De Cesare, M.3
  • 25
    • 0041854306 scopus 로고    scopus 로고
    • The metabolites of the cardioprotective drug dexrazoxane do not protect myocytes from doxorubicin-induced cytotoxicity
    • Hasinoff BB, Schroeder PE, Patel D. The metabolites of the cardioprotective drug dexrazoxane do not protect myocytes from doxorubicin-induced cytotoxicity. Mol Pharmacol. 2003;64:670-8.
    • (2003) Mol Pharmacol , vol.64 , pp. 670-678
    • Hasinoff, B.B.1    Schroeder, P.E.2    Patel, D.3
  • 26
    • 0021893818 scopus 로고
    • Comparison of the effectiveness of (+/-)-1,2-bis(3,5-dioxopiperazinyl-1- yl)propane (ICRF-187) and N-acetylcysteine in preventing chronic doxorubicin cardiotoxicity in beagles
    • Herman EH, Ferrans VJ, Myers CE, Van Vleet JF. Comparison of the effectiveness of (+/-)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane (ICRF-187) and N-acetylcysteine in preventing chronic doxorubicin cardiotoxicity in beagles. Cancer Res. 1985;45:276-81.
    • (1985) Cancer Res , vol.45 , pp. 276-281
    • Herman, E.H.1    Ferrans, V.J.2    Myers, C.E.3    Van Vleet, J.F.4
  • 27
    • 0035029212 scopus 로고    scopus 로고
    • Epirubicin glucuronidation is catalyzed by human UDP- glucuronosyltransferase 2B7
    • Innocenti F, Iyer L, Ramirez J, Green MD, Ratain MJ. Epirubicin glucuronidation is catalyzed by human UDP-glucuronosyltransferase 2B7. Drug Metab Dispos. 2001;29:686-92.
    • (2001) Drug Metab Dispos , vol.29 , pp. 686-692
    • Innocenti, F.1    Iyer, L.2    Ramirez, J.3    Green, M.D.4    Ratain, M.J.5
  • 28
    • 0030931797 scopus 로고    scopus 로고
    • A novel cardiac-restricted target for doxorubicin CARP, a nuclear modulator of gene expression in cardiac progenitor cells and cardiomyocytes
    • Jeyaseelan R, Poizat C, Baker RK, et al. A novel cardiac-restricted target for doxorubicin CARP, a nuclear modulator of gene expression in cardiac progenitor cells and cardiomyocytes. J Biol Chem. 1997;272:22800-8.
    • (1997) J Biol Chem , vol.272 , pp. 22800-22808
    • Jeyaseelan, R.1    Poizat, C.2    Baker, R.K.3
  • 30
    • 21244477458 scopus 로고    scopus 로고
    • Preclinical pharmacokinetics and oral bioavailability of BMS-310705, a novel epothilone B analog
    • Kamath AV, Chang M, Lee FY, Zhang Y, Marathe PH. Preclinical pharmacokinetics and oral bioavailability of BMS-310705, a novel epothilone B analog. Cancer Chemother Pharmacol; 2005;56:145-53.
    • (2005) Cancer Chemother Pharmacol , vol.56 , pp. 145-153
    • Kamath, A.V.1    Chang, M.2    Lee, F.Y.3    Zhang, Y.4    Marathe, P.H.5
  • 31
    • 0026937901 scopus 로고
    • Properties of Cremophor EL micelles probed by fluorescence
    • Kessel D. Properties of Cremophor EL micelles probed by fluorescence. Photochem Photobiol. 1992;56:447-51.
    • (1992) Photochem Photobiol , vol.56 , pp. 447-451
    • Kessel, D.1
  • 33
    • 0034119194 scopus 로고    scopus 로고
    • Doxorubicin metabolism and toxicity in human myocardium: Role of cytoplasmic deglycosidation and carbonyl reduction
    • Licata S, Saponiero A, Mordente A, Minotti G. Doxorubicin metabolism and toxicity in human myocardium: role of cytoplasmic deglycosidation and carbonyl reduction. Chem Res Toxicol. 2000;13:414-20.
    • (2000) Chem Res Toxicol , vol.13 , pp. 414-420
    • Licata, S.1    Saponiero, A.2    Mordente, A.3    Minotti, G.4
  • 34
    • 0037087687 scopus 로고    scopus 로고
    • Doxorubicin administration by continuous infusion is not cardioprotective: The Dana-Farber 91-01 acute lymphoblastic leukemia protocol
    • Lipshultz SE, Giantris AL, Lipsitz SR, et al. Doxorubicin administration by continuous infusion is not cardioprotective: the Dana-Farber 91-01 acute lymphoblastic leukemia protocol. J Clin Oncol. 2002;20:1677-82.
    • (2002) J Clin Oncol , vol.20 , pp. 1677-1682
    • Lipshultz, S.E.1    Giantris, A.L.2    Lipsitz, S.R.3
  • 35
    • 0141706939 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of unbound docetaxel: Role of polysorbate 80 and serum proteins
    • Loos WJ, Baker SD, Verweij J, Boonstra JG, Sparreboom A. Clinical pharmacokinetics of unbound docetaxel: role of polysorbate 80 and serum proteins. Clin Pharmacol Ther. 2003;74:364-71.
    • (2003) Clin Pharmacol Ther , vol.74 , pp. 364-371
    • Loos, W.J.1    Baker, S.D.2    Verweij, J.3    Boonstra, J.G.4    Sparreboom, A.5
  • 36
    • 12144285977 scopus 로고    scopus 로고
    • Phase I clinical and pharmacokinetic study of BMS-247550, a novel derivative of epothilone B, in solid tumors
    • Mani S, McDaid H, Hamilton A, et al. Phase I clinical and pharmacokinetic study of BMS-247550, a novel derivative of epothilone B, in solid tumors. Clin Cancer Res. 2004;10:1289-98.
    • (2004) Clin Cancer Res , vol.10 , pp. 1289-1298
    • Mani, S.1    McDaid, H.2    Hamilton, A.3
  • 37
    • 0024588205 scopus 로고
    • Oxidative and non-oxidative mechanisms in the inactivation of cardiac mitochondrial electron transport chain components by doxorubicin
    • Marcillat O, Zhang Y, Davies KJ. Oxidative and non-oxidative mechanisms in the inactivation of cardiac mitochondrial electron transport chain components by doxorubicin. Biochem J. 1989;259:181-9.
    • (1989) Biochem J , vol.259 , pp. 181-189
    • Marcillat, O.1    Zhang, Y.2    Davies, K.J.3
  • 38
    • 21144435932 scopus 로고    scopus 로고
    • Adjuvant docetaxel for nodepositive breast cancer
    • Breast Cancer International Research Group 001 Investigators
    • Martin M, Pienkowski T, Mackey J, et al. Breast Cancer International Research Group 001 Investigators. Adjuvant docetaxel for nodepositive breast cancer. N Engl J Med. 2005;352:2302-13.
    • (2005) N Engl J Med , vol.352 , pp. 2302-2313
    • Martin, M.1    Pienkowski, T.2    Mackey, J.3
  • 39
    • 18644370534 scopus 로고    scopus 로고
    • Expression and localization of P-glycoprotein in human heart: Effects of cardiomyopathy
    • Meissner K, Sperker B, Karsten C, et al. Expression and localization of P-glycoprotein in human heart: effects of cardiomyopathy. J Histochem Cytochem. 2002;50:1351-6.
    • (2002) J Histochem Cytochem , vol.50 , pp. 1351-1356
    • Meissner, K.1    Sperker, B.2    Karsten, C.3
  • 40
    • 0028902346 scopus 로고
    • Secondary alcohol metabolites mediate iron delocalization in cytosolic fractions of myocardial biopsies exposed to anticancer anthracyclines. Novel linkage between anthracycline metabolism and iron-induced cardiotoxicity
    • Minotti G, Cavaliere AF, Mordente A, et al. Secondary alcohol metabolites mediate iron delocalization in cytosolic fractions of myocardial biopsies exposed to anticancer anthracyclines. Novel linkage between anthracycline metabolism and iron-induced cardiotoxicity. J Clin Invest. 1995;95:1595-605.
    • (1995) J Clin Invest , vol.95 , pp. 1595-1605
    • Minotti, G.1    Cavaliere, A.F.2    Mordente, A.3
  • 41
    • 0032965572 scopus 로고    scopus 로고
    • Role of iron in anthracycline cardiotoxicity: New tunes for an old song?
    • Minotti G, Cairo G, Monti E. Role of iron in anthracycline cardiotoxicity: new tunes for an old song? FASEB J. 1999;13:199-212.
    • (1999) FASEB J , vol.13 , pp. 199-212
    • Minotti, G.1    Cairo, G.2    Monti, E.3
  • 42
    • 0005496976 scopus 로고    scopus 로고
    • Doxorubicin metabolism to toxic species in human myocardium: Stimulation by paclitaxel and docetaxel but not BMS 184476 or BMS 188797
    • Minotti G, Giancristofaro G, Menna P, Salvatorelli E, Licata S, Gianni L. Doxorubicin metabolism to toxic species in human myocardium: stimulation by paclitaxel and docetaxel but not BMS 184476 or BMS 188797. Clin Cancer Res. 2000a;6:360A.
    • (2000) Clin Cancer Res , vol.6
    • Minotti, G.1    Giancristofaro, G.2    Menna, P.3    Salvatorelli, E.4    Licata, S.5    Gianni, L.6
  • 43
    • 17744365161 scopus 로고    scopus 로고
    • Anthracycline metabolism and toxicity in human myocardium: Comparisons between doxorubicin, epirubicin, and a novel disaccharide analogue with areduced level of formation and [4Fe-4S] reactivity of its secondary alcohol metabolite
    • Minotti G, Licata S, Saponiero A, et al. Anthracycline metabolism and toxicity in human myocardium: comparisons between doxorubicin, epirubicin, and a novel disaccharide analogue with areduced level of formation and [4Fe-4S] reactivity of its secondary alcohol metabolite. Chem Res Toxicol. 2000b;13:1336-41.
    • (2000) Chem Res Toxicol , vol.13 , pp. 1336-1341
    • Minotti, G.1    Licata, S.2    Saponiero, A.3
  • 44
    • 0034905407 scopus 로고    scopus 로고
    • Paclitaxel and docetaxel enhance the metabolism of doxorubicin to toxic species in human myocardium
    • Minotti G, Saponiero A, Licata S, et al. Paclitaxel and docetaxel enhance the metabolism of doxorubicin to toxic species in human myocardium. Clin Cancer Res. 2001a;7:1511-5.
    • (2001) Clin Cancer Res , vol.7 , pp. 1511-1515
    • Minotti, G.1    Saponiero, A.2    Licata, S.3
  • 45
    • 0035192387 scopus 로고    scopus 로고
    • Impairment of myocardial contractility by anticancer anthracyclines: Role of secondary alcohol metabolites and evidence of reduced toxicity by a novel disaccharide analogue
    • Minotti G, Parlani M, Salvatorelli E, et al. Impairment of myocardial contractility by anticancer anthracyclines: role of secondary alcohol metabolites and evidence of reduced toxicity by a novel disaccharide analogue. Br J Pharmacol. 2001b;134:1271-8.
    • (2001) Br J Pharmacol , vol.134 , pp. 1271-1278
    • Minotti, G.1    Parlani, M.2    Salvatorelli, E.3
  • 46
    • 2642566088 scopus 로고    scopus 로고
    • Anthracyclines: Molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity
    • Minotti G, Menna P, Salvatorelli E, Cairo G, Gianni L. Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol Rev. 2004;56:185-229.
    • (2004) Pharmacol Rev , vol.56 , pp. 185-229
    • Minotti, G.1    Menna, P.2    Salvatorelli, E.3    Cairo, G.4    Gianni, L.5
  • 47
    • 0041694227 scopus 로고    scopus 로고
    • Anthracycline secondary alcohol metabolite formation in human or rabbit heart: Biochemical aspects and pharmacologic implications
    • Mordente A, Minotti G, Martorana GE, Silvestrini A, Giardina B, Meucci E. Anthracycline secondary alcohol metabolite formation in human or rabbit heart: biochemical aspects and pharmacologic implications. Biochem Pharmacol. 2003;66:989-98.
    • (2003) Biochem Pharmacol , vol.66 , pp. 989-998
    • Mordente, A.1    Minotti, G.2    Martorana, G.E.3    Silvestrini, A.4    Giardina, B.5    Meucci, E.6
  • 48
    • 0020583667 scopus 로고
    • A randomized controlled trial assessing the prevention of doxorubicin cardiomyopathy by Nacetylcysteine
    • Myers C, Bonow R, Palmieri S, et al. A randomized controlled trial assessing the prevention of doxorubicin cardiomyopathy by Nacetylcysteine. Semin Oncol. 1983;10:53-5.
    • (1983) Semin Oncol , vol.10 , pp. 53-55
    • Myers, C.1    Bonow, R.2    Palmieri, S.3
  • 49
    • 0037445247 scopus 로고    scopus 로고
    • Docetaxel and doxorubicin compared with doxorubicin and cyclophosphamide as first-line chemotherapy for metastatic breast cancer: Results of a randomized, multicenter, Phase III Trial
    • Nabholtz JM, Falkson C, Campos D, et al. Docetaxel and doxorubicin compared with doxorubicin and cyclophosphamide as first-line chemotherapy for metastatic breast cancer: results of a randomized, multicenter, Phase III Trial. J Clin Oncol. 2003;21:968-75.
    • (2003) J Clin Oncol , vol.21 , pp. 968-975
    • Nabholtz, J.M.1    Falkson, C.2    Campos, D.3
  • 50
    • 0842282637 scopus 로고    scopus 로고
    • Taxane-mediated antiangiogenesis in vitro: Influence of formulation vehicles and binding proteins
    • Ng SSW, Figg WD, Sparreboom A. Taxane-mediated antiangiogenesis in vitro: influence of formulation vehicles and binding proteins. Cancer Res. 2004;64:821-4.
    • (2004) Cancer Res , vol.64 , pp. 821-824
    • Ng, S.S.W.1    Figg, W.D.2    Sparreboom, A.3
  • 51
    • 0242321133 scopus 로고    scopus 로고
    • Protection from doxorubicin-induced cardiac toxicity in mice with a null allele of carbonyl reductase 1
    • Olson LE, Bedja D, Alvey SJ, Cardounel AJ, Gabrielson KL, Reeves RH. Protection from doxorubicin-induced cardiac toxicity in mice with a null allele of carbonyl reductase 1. Cancer Res. 2003;63:6602-6.
    • (2003) Cancer Res , vol.63 , pp. 6602-6606
    • Olson, L.E.1    Bedja, D.2    Alvey, S.J.3    Cardounel, A.J.4    Gabrielson, K.L.5    Reeves, R.H.6
  • 52
    • 0025051505 scopus 로고
    • Doxorubicin cardiotoxicity: Analysis of prevailing hypotheses
    • Olson RD, Mushlin PS. Doxorubicin cardiotoxicity: analysis of prevailing hypotheses. FASEB J. 1990;4:3076-86.
    • (1990) FASEB J , vol.4 , pp. 3076-3086
    • Olson, R.D.1    Mushlin, P.S.2
  • 53
    • 0037442806 scopus 로고    scopus 로고
    • +-ATPase impair the preferential accumulation of daunomycin in lysosomes and reverse the resistance to anthracyclines in drug-resistant renal epithelial cells
    • +-ATPase impair the preferential accumulation of daunomycin in lysosomes and reverse the resistance to anthracyclines in drug-resistant renal epithelial cells. Biochem J. 2003;370:185-93.
    • (2003) Biochem J , vol.370 , pp. 185-193
    • Ouar, Z.1    Bens, M.2    Vignes, C.3
  • 54
    • 0031754801 scopus 로고    scopus 로고
    • Improved efficacy and enlarged spectrum of activity of a novel anthracycline disaccharide analogue of doxorubicin against human tumor xenografts
    • Pratesi G, De Cesare M, Caserini C, et al. Improved efficacy and enlarged spectrum of activity of a novel anthracycline disaccharide analogue of doxorubicin against human tumor xenografts. Clin Cancer Res. 1998;4:2833-9.
    • (1998) Clin Cancer Res , vol.4 , pp. 2833-2839
    • Pratesi, G.1    De Cesare, M.2    Caserini, C.3
  • 55
    • 0027787743 scopus 로고
    • Pharmacokinetics and metabolism of anthracyclines
    • Robert J, Gianni L. Pharmacokinetics and metabolism of anthracyclines. Cancer Surv. 1993;17:219-52.
    • (1993) Cancer Surv , vol.17 , pp. 219-252
    • Robert, J.1    Gianni, L.2
  • 56
    • 0031040149 scopus 로고    scopus 로고
    • The development and clinical utility of the taxane class of antimicrotubule chemotherapy agents
    • Rowinsky EK. The development and clinical utility of the taxane class of antimicrotubule chemotherapy agents. Annu Rev Med. 1997;48:353-74.
    • (1997) Annu Rev Med , vol.48 , pp. 353-374
    • Rowinsky, E.K.1
  • 58
    • 10744224134 scopus 로고    scopus 로고
    • Chronic cardiotoxicity of anticancer anthracyclines in the rat: Role of secondary alcohol metabolites and reduced toxicity by a novel anthracycline with impaired metabolite formation and reactivity
    • Sacco G, Giampietro R, Salvatorelli E, et al. Chronic cardiotoxicity of anticancer anthracyclines in the rat: role of secondary alcohol metabolites and reduced toxicity by a novel anthracycline with impaired metabolite formation and reactivity. Br J Pharmacol. 2003;139:641-51.
    • (2003) Br J Pharmacol , vol.139 , pp. 641-651
    • Sacco, G.1    Giampietro, R.2    Salvatorelli, E.3
  • 59
    • 33845624566 scopus 로고    scopus 로고
    • BMS 247550 does not enhance doxorubicinol formation in human myocardium
    • Salvatorelli E, Minotti G, Vigano L, et al. BMS 247550 does not enhance doxorubicinol formation in human myocardium. Proc Am Assoc Cancer Res. 2004;45:5432A.
    • (2004) Proc Am Assoc Cancer Res , vol.45
    • Salvatorelli, E.1    Minotti, G.2    Vigano, L.3
  • 60
    • 33744959330 scopus 로고    scopus 로고
    • Defective one or two electron reduction of the anticancer anthracycline epirubicin in human heart: Relative importance of vesicular sequestration and impaired efficiency of electron addition
    • Salvatorelli E, Guarnieri S, Menna P, et al. Defective one or two electron reduction of the anticancer anthracycline epirubicin in human heart: relative importance of vesicular sequestration and impaired efficiency of electron addition. J Biol Chem. 2006a;281:10990-1001.
    • (2006) J Biol Chem , vol.281 , pp. 10990-11001
    • Salvatorelli, E.1    Guarnieri, S.2    Menna, P.3
  • 61
    • 33745263272 scopus 로고    scopus 로고
    • Paclitaxel and docetaxel stimulation of doxorubicinol formation in the human heart: Implications for cardiotoxicity of doxorubicin-taxane chemotherapies
    • Salvatorelli E, Menna P, Cascegna S, et al. Paclitaxel and docetaxel stimulation of doxorubicinol formation in the human heart: implications for cardiotoxicity of doxorubicin-taxane chemotherapies. J Pharmacol Exp Ther. 2006b;318(1):424-33.
    • (2006) J Pharmacol Exp Ther , vol.318 , Issue.1 , pp. 424-433
    • Salvatorelli, E.1    Menna, P.2    Cascegna, S.3
  • 62
    • 0036018908 scopus 로고    scopus 로고
    • Phase I study of MEN-10755, a new anthracycline in patients with solid tumours: A report from the european organization for research and treatment of cancer, early clinical studies group
    • Schrijvers D, Bos AM, Dyck J, et al. Phase I study of MEN-10755, a new anthracycline in patients with solid tumours: a report from the european organization for research and treatment of cancer, early clinical studies group. Ann Oncol. 2002;13:385-91.
    • (2002) Ann Oncol , vol.13 , pp. 385-391
    • Schrijvers, D.1    Bos, A.M.2    Dyck, J.3
  • 63
    • 10744229319 scopus 로고    scopus 로고
    • Phase IB and pharmacological study of the novel taxane BMS-184476 in combination with doxorubicin
    • Sessa C, Perotti A, Salvatorelli E, et al. Phase IB and pharmacological study of the novel taxane BMS-184476 in combination with doxorubicin. Eur J Cancer. 2004;40:563-70.
    • (2004) Eur J Cancer , vol.40 , pp. 563-570
    • Sessa, C.1    Perotti, A.2    Salvatorelli, E.3
  • 64
  • 66
    • 0031020377 scopus 로고    scopus 로고
    • Aldose reductase induction: A novel response to oxidative stress of smooth muscle cells
    • Spycher SE, Tabataba-Vakili S, O'Donnell VB, Palomba L, Azzi A. Aldose reductase induction: a novel response to oxidative stress of smooth muscle cells. FASEB J. 1997;11:181-8.
    • (1997) FASEB J , vol.11 , pp. 181-188
    • Spycher, S.E.1    Tabataba-Vakili, S.2    O'Donnell, V.B.3    Palomba, L.4    Azzi, A.5
  • 67
    • 0027772910 scopus 로고
    • Concentrations of doxorubicin and its metabolites in human autopsy heart and other tissues
    • Stewart DJ, Grewaal D, Green RM, et al. Concentrations of doxorubicin and its metabolites in human autopsy heart and other tissues. Anticancer Res. 1993;13:1945-52.
    • (1993) Anticancer Res , vol.13 , pp. 1945-1952
    • Stewart, D.J.1    Grewaal, D.2    Green, R.M.3
  • 68
    • 0037336991 scopus 로고    scopus 로고
    • The crystal structure of the complex between a disaccharide anthracycline and the DNA hexamer d(CGATCG) reveals two different binding sites involving two DNA duplexes
    • Temperini C, Messori L, Orioli P, Di Bugno C, Animati F, Giovanni U. The crystal structure of the complex between a disaccharide anthracycline and the DNA hexamer d(CGATCG) reveals two different binding sites involving two DNA duplexes. Nucleic Acids Res. 2003;31:1464-9.
    • (2003) Nucleic Acids Res , vol.31 , pp. 1464-1469
    • Temperini, C.1    Messori, L.2    Orioli, P.3    Di Bugno, C.4    Animati, F.5    Giovanni, U.6
  • 69
    • 6844242343 scopus 로고    scopus 로고
    • Pharmacology of chronic oral daily administration of idarubicin
    • Toffoli G, Sorio R, Aita P, et al. Pharmacology of chronic oral daily administration of idarubicin. Haematologica. 1997;82:1-3.
    • (1997) Haematologica , vol.82 , pp. 1-3
    • Toffoli, G.1    Sorio, R.2    Aita, P.3
  • 70
    • 0018838651 scopus 로고
    • Cardiac disease induced by chronic adriamycin administration in dogs and an evaluation of vitamin E and selenium as cardioprotectants
    • van Vleet JF, Ferrans VJ, Weirich WE. Cardiac disease induced by chronic adriamycin administration in dogs and an evaluation of vitamin E and selenium as cardioprotectants. Am J Pathol. 1980;99:13-42.
    • (1980) Am J Pathol , vol.99 , pp. 13-42
    • Van Vleet, J.F.1    Ferrans, V.J.2    Weirich, W.E.3
  • 71
    • 0035863469 scopus 로고    scopus 로고
    • Cumulative and irreversible cardiac mitochondrial dysfunction induced by doxorubicin
    • Zhou S, Starkov A, Froberg MK, Leino RL, Wallace KB. Cumulative and irreversible cardiac mitochondrial dysfunction induced by doxorubicin. Cancer Res. 2001;61:771-7.
    • (2001) Cancer Res , vol.61 , pp. 771-777
    • Zhou, S.1    Starkov, A.2    Froberg, M.K.3    Leino, R.L.4    Wallace, K.B.5
  • 72
    • 0037274873 scopus 로고    scopus 로고
    • Cardiac toxicity of antineoplastic anthracyclines
    • Zucchi R, Danesi R. Cardiac toxicity of antineoplastic anthracyclines. Curr Med Chem. 2003;3:151-71.
    • (2003) Curr Med Chem , vol.3 , pp. 151-171
    • Zucchi, R.1    Danesi, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.