Lack of effect of coumarin on the formation of micronuclei in an in vivo mouse micronucleus assay

Food and Chemical Toxicology

Volumn 39, Issue 8, 2001, Pages 837-841

  Api, A M ^a  

^a RESEARCH INSTITUTE FOR FRAGRANCE MATERIALS   (United States)

Author keywords

Coumarin; Genotoxicity; Mouse micronucleus

Indexed keywords

CORN OIL; COUMARIN; DRUG VEHICLE; MITOMYCIN C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG EFFECT; ERYTHROCYTE; FEEDING; FEMALE; GENOTOXICITY; MALE; MICRONUCLEUS; MICRONUCLEUS TEST; MOUSE; NONHUMAN;

ADMINISTRATION, ORAL; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTICOAGULANTS; BONE MARROW CELLS; COUMARINS; DNA DAMAGE; FEMALE; MALE; MICE; MICRONUCLEUS TESTS; MITOMYCIN;

ANIMALIA; ZEA MAYS;

EID: 0034968709     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-6915(01)00024-2     Document Type: Article

References (32)

1. Lack of effect of coumarin on unscheduled DNA synthesis in precision-cut human liver slices
2. Effects of antioxidants on the mutagenicity of benz(o)pyrene and 7,12-dimethybenzanthracene
3. Effect of coumarin following perinatal and chronic exposure in Sprague-Dawley rats and CD-1 mice
4. Phase II study of coumarin and cimetidine in patients with metastatic renal carcinoma
5. Lack of effect of coumarin on unscheduled DNA synthesis in the in vivo rat hepatocyte DNA repair assay
6. Coumarin toxicity in different strains of mice
7. Screening of tobacco smoke constituents for mutagenicity using the Ames test
8. Activite anti-inflammatoire experimentale de coumarines, indane-diones et acyl-indane-diones apparentees aux anticoagulants oraux
9. 14C]coumarin by rats and by human volunteers under simulated conditions of use in fragrances
10. Coumarin chemoprevention against aflatoxin beta (1)-induced gene mutation in a mammalian cell system: A species difference in mutagen activation and protection with chick embryo and rat liver S9
11. Co-mutagenicity of coumarin (1,2-benzopyrone) with aflatoxin B1 and human liver S9 in mammalian cells
12. Comparative metabolism and pharmacokinetics of (14)C-coumarin in the mouse after gavage or dietary administration
13. Coumarin derivatives for medicinal purpose. V. Sedative and hypnotic actions
14. Food flavourings and compounds of related structure I. Acute oral toxicity
15. Coumarin derivatives for medicinal purposes. XVII. Pharmacological studies on coumarin derivatives having biological activity
16. Coumarin metabolism, toxicity and carcinogenicity: Relevance for human risk assessment
17. Treatment of metastatic renal carcinoma with coumarin (1,2-benzopyrone) and cimetidine: A pilot study
18. Coumarin inhibits micronuclei formation induced by benzo(a)pyrene in male but not female ICR mice
19. Toxicology and Carcinogenic Studies of Coumarin (CAS No. 91-64-5) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
20. Assessment of the mutagenic potential of coumarin in histidine-dependent strains of Salmonella typhimurium
21. Chromosome aberrations of ortho-hydroxyphenylacetic acid in Chinese hamster ovary (CHO) cells
22. Salmonella/mammalian-microsome plate incorporation mutagenicity assay. (Ames test)
23. Chromosome aberrations of 7-hydroxycoumarin in Chinese hamster ovary (CHO) cells
24. Unscheduled DNA synthesis of ortho-hydroxyphenylacetic acid and 7-hydroxycoumarin in rat primary hepatocytes
25. Effect of antimutagenic flavorings on SCEs induced by chemical mutagens in cultured Chinese hamster cells
26. The micronucleus test
27. Mutagenicity of coumarin and related compounds for Salmonella typhimurium
28. Inhibition of chemical carcinogen induced neoplasia by coumarins and α-angelicalactone