Alveolar epithelial differentiation of human induced pluripotent stem cells in a rotating bioreactor

Biomaterials

Volumn 35, Issue 2, 2014, Pages 699-710

  Ghaedi, Mahboobe ^a,b   Mendez, Julio J ^a,b   Bove, Peter F ^c   Sivarapatna, Amogh ^a,b   Raredon, Micha Sam B ^a,b   Niklason, Laura E ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Yale University   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Air liquid interface; ALI; Alveolar epithelium; Bioreactor; HATI; HATII; Induced pluripotent stem (iPS); IPSC ATII

Indexed keywords

BIOCONVERSION; BIOREACTORS; CYTOLOGY; LIQUIDS; PHASE INTERFACES; POLYMERASE CHAIN REACTION; STEM CELLS; TISSUE; TISSUE ENGINEERING;

AIR LIQUID INTERFACES; ALVEOLAR EPITHELIUMS; HATI; HATII; IPSC-ATII; PLURIPOTENT;

CELL ENGINEERING;

CAVEOLIN 1;

ARTICLE; BIOREACTOR; BIOREACTOR DESIGN; CELL DIFFERENTIATION; CELL ISOLATION; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG ALVEOLUS CELL; LUNG ALVEOLUS EPITHELIUM; MOLECULE; NANOFABRICATION; PHENOTYPE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE ENGINEERING;

IPS;

AIR-LIQUID INTERFACE; ALI; ALVEOLAR EPITHELIUM; BIOREACTOR; HATI; HATII; HUMAN ALVEOLAR TYPE I; HUMAN ALVEOLAR TYPE II; INDUCED PLURIPOTENT STEM (IPS); IPSC-ATII; IPSC-DERIVED ALVEOLAR TYPE II;

AQUAPORIN 5; BIOREACTORS; CAVEOLIN 1; CELL DIFFERENTIATION; CELLS, CULTURED; EPITHELIAL CELLS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MEMBRANE PROTEINS; PULMONARY ALVEOLI;

EID: 84886749971     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.10.018     Document Type: Article

References (36)

1. Rawlins E.L., Hogan B.L. Epithelial stem cells of the lung: privileged few or opportunities for many?. Development 2006, 133(13):2455-2465.
2. Van Haute L., De Block G., Liebaers I., Sermon K., De Rycke M. Generation of lung epithelial-like tissue from human embryonic stem cells. Respir Res 2009, 10:105.
3. Ali N.N., Edgar A.J., Samadikuchaksaraei A., Timson C.M., Romanska H.M., Polak J.M., et al. Derivation of type II alveolar epithelial cells from murine embryonic stem cells. Tissue Eng 2002, 8(4):541-550.
4. Dobbs L.G. Isolation and culture of alveolar type II cells. Am J Phys 1990, 258(4 Pt 1):L134-L147.
5. Fulcher M.L., Gabriel S., Burns K.A., Yankaskas J.R., Randell S.H. Well-differentiated human airway epithelial cell cultures. Methods Mol Med 2005, 107:183-206.
6. Petersen T.H., Calle E.A., Colehour M.B., Niklason L.E. Bioreactor for the long-term culture of lung tissue. Cell Transplant 2011, 20(7):1117-1126.
7. Kotton D.N. Next-generation regeneration: the hope and hype of lung stem cell research. Am J Respir Crit Care Med 2012, 185(12):1255-1260.
8. Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131(5):861-872.
9. Yu J., Vodyanik M.A., Smuga-Otto K., Antosiewicz-Bourget J., Frane J.L., Tian S., et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007, 318(5858):1917-1920.
10. Nishikawa S., Goldstein R.A., Nierras C.R. The promise of human induced pluripotent stem cells for research and therapy. Nat Rev Mol Cell Biol 2008, 9(9):725-729.
11. Mou H., Zhao R., Sherwood R., Ahfeldt T., Lapey A., Wain J., et al. Generation of multipotent lung and airway progenitors from mouse ESCs and patient-specific cystic fibrosis iPSCs. Cell Stem Cell 2012, 10(4):385-397.
12. Green M.D., Chen A., Nostro M.C., d'Souza S.L., Schaniel C., Lemischka I.R., et al. Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells. Nat Biotechnol 2011, 29(3):267-272.
13. Badylak S.F., Weiss D.J., Caplan A., Macchiarini P. Engineered whole organs and complex tissues. Lancet 2012, 379(9819):943-952.
14. Longmire T.A., Ikonomou L., Hawkins F., Christodoulou C., Cao Y., Jean J.C., et al. Efficient derivation of purified lung and thyroid progenitors from embryonic stem cells. Cell Stem Cell. 2012, 10(4):398-411.
15. Wang D., Haviland D.L., Burns A.R., Zsigmond E., Wetsel R.A. Apure population of lung alveolar epithelial type II cells derived from human embryonic stem cells. Proc Natl Acad Sci U S A 2007, 104(11):4449-4454.
16. Samadikuchaksaraei A., Cohen S., Isaac K., Rippon H.J., Polak J.M., Bielby R.C., et al. Derivation of distal airway epithelium from human embryonic stem cells. Tissue Eng 2006, 12(4):867-875.
17. Ghaedi M., Calle E.S., Mendez J.J., Gard A.L., Balesterini J., Booth A.J., et al. Human iPS cell-derived alveolar epithelium repopulates lung extracellular matrix. JCI 2013, 123(11). 10.1172/JCI68793.
18. Otto W.R. Lung stem cells. Int J Exp Pathol 1997, 78(5):291-310.
19. Asselin-Labat M.L., Filby C.E. Adult lung stem cells and their contribution to lung tumourigenesis. Open Biol 2012, 2:120094.
20. Barkauskas C.E., Cronce M.J., Rackley C.R., Bowie E.J., Keene D.R., Stripp B.R., et al. Type 2 alveolar cells are stem cells in adult lung. JClin Invest 2013, 123(7):3025-3036.
21. Fujino N., Kubo H., Suzuki T., Ota C., Hegab A.E., He M., et al. Isolation of alveolar epithelial type II progenitor cells from adult human lungs. Lab Invest 2011, 91(3):363-378.
22. Fehrenbach H. Alveolar epithelial type II cell: defender of the alveolus revisited. Respir Res 2001, 2(1):33-46.
23. Banerjee E.R., Laflamme M.A., Papayannopoulou T., Kahn M.M.C., Henderson W.R. Human embryonic stem cells differentiated to lung lineage-specific cells ameliorate pulmonary fibrosis in a xenograft transplant mouse model. PLoS One 2012, 7(3):e33165.
24. Alcorn D., Adamson T.M., Lambert T.F., Maloney J.E., Ritchie B.C., Robinson P.M. Morphological effects of chronic tracheal ligation and drainage in the fetal lamb lung. JAnat 1977, 123(Pt 3):649-660.
25. Ostrowski L.E., Nettesheim P. Inhibition of ciliated cell differentiation by fluid submersion. Exp Lung Res 1995, 21(6):957-970.
26. Gutierrez J.A., Gonzalez R.F., Dobbs L.G. Mechanical distension modulates pulmonary alveolar epithelial phenotypic expression invitro. Am J Phys 1998, 274(2 Pt 1):L196-L202.
27. Kubo A., Shinozaki K., Shannon J.M., Kouskoff V., Kennedy M., Woo S., et al. Development of definitive endoderm from embryonic stem cells in culture. Development 2004, 131(7):1651-1662.
28. Duan Y., Ma X., Zou W., Wang C., Bahbahan I.S., Ahuja T.P., et al. Differentiation and characterization of metabolically functioning hepatocytes from human embryonic stem cells. Stem Cells 2010, 28(4):674-686.
29. Ghaedi M., Duan Y., Zern M.A., Revzin A. Hepatic differentiation of human embryonic stem cells on growth factor-containing surfaces. JTissue Eng Regen Med 2012, 10.1002/term.1595.
30. Bove P.F., Grubb B.R., Okada S.F., Ribeiro C.M., Rogers T.D., Randell S.H., et al. Human alveolar type II cells secrete and absorb liquid in response to local nucleotide signaling. JBiol Chem 2010, 285(45):34939-34949.
31. Raredon M.S., Calle E.A., Niklason L.E. Arotating bioreactor for large-scale culture and differentiation of respiratory epithelium. Cell Transplant 2013, under revision.
32. Wong A.P., Bear C.E., Chin S., Pasceri P., Thompson T.O., Huan L.J., et al. Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTRTR protein. Nat Biotechnol 2012, 30(9):876-882.
33. Lin H., Li H., Cho H.J., Bian S., Roh H.J., Lee M.K., et al. Air-liquid interface (ALI) culture of human bronchial epithelial cell monolayers as an invitro model for airway drug transport studies. JPharm Sci 2007, 96(2):341-350.
34. Hermanns M.I., Unger R.E., Kehe K., Peters K., Kirkpatrick C.J. Lung epithelial cell lines in coculture with human pulmonary microvascular endothelial cells: development of an alveolo-capillary barrier invitro. Lab Invest 2004, 84(6):736-752.
35. Huh D., Matthews B.D., Mammoto A., Montoya-Zavala M., Hsin H.Y., Ingber D.E. Reconstituting organ-level lung functions on a chip. Science 2010, 328(5986):1662-1668.
36. Macchiarini P., Jungebluth P., Go T., Asnaghi M.A., Rees L.E., Cogan T.A., et al. Clinical transplantation of a tissue-engineered airway. Lancet 2008, 372(9655):2023-2030.