Mechanical distension modulates pulmonary alveolar epithelial phenotypic expression in vitro

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 274, Issue 2 18-2, 1998, Pages

  Gutierrez, Jorge A ^a   Gonzalez, Robert F ^b   Dobbs, Leland G ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Gene expression; Mechanical stretch; Type I cell; Type II cell

Indexed keywords

COMPLEMENTARY DNA; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MEMBRANE PROTEIN; MESSENGER RNA; PROTEIN; SURFACTANT;

AGAR GEL ELECTROPHORESIS; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HYBRIDIZATION; LUNG ALVEOLUS CELL TYPE 1; LUNG ALVEOLUS CELL TYPE 2; LUNG ALVEOLUS EPITHELIUM; MALE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOUTHERN BLOTTING; STRETCHING;

EID: 0031912780     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1998.274.2.l196     Document Type: Article

References (20)

1. Alcorn, D., T. M. Andersen, T. F. Lambert, J. E. Maloney, B. C. Ritchie, and P. M. Robinson. Morphologic effects of chronic tracheal ligation and drainage in the fetal lamb lung. J. Anat. 123: 649-660, 1977.
2. Boggaram, V., M. E. Smith, and C. R. Mendelson. Regulation of expression of the gene encoding the major surfactant protein (SP-A) in human fetal lung in vitro. Disparate effects of glucocorticoids on transcription and on mRNA stability. J. Biol. Chem. 264: 11421-11427, 1989.
3. Danto, S. I., J. M. Shannon, Z. Borok, S. M. Zabski, and E. D. Crandall. Reversible transdifferentiation of alveolar epithelial cells. Am. J. Respir. Cell Mol. Biol. 12: 497-502, 1995.
4. Danto, S. I., S. M. Zabski, and E. D. Crandall. Reactivity of alveolar epithelial cells in primary culture with type I cell monoclonal antibodies. Am. J. Respir. Cell Mol. Biol. 6: 296-306, 1992.
5. Diamond, S. L., J. B. Sharefkin, C. Dieffenbach, K. L. Frasier-Scott, V. McIntire, and S. G. Eskin. Tissue plasminogen activator messenger RNA levels increase in cultured human endothelial cells exposed to laminar shear stress. J. Cell. Physiol. 143: 364-371, 1990.
6. Diglio, C. A., and Y. Kikkawa. The type II epithelial cells of the lung. IV. Adaptation and behavior of isolated type II cells in culture. Lab. Invest. 37: 622-631, 1977.
7. Dobbs, L. G., R. Gonzalez, and M. C. Williams. An improved method for isolating type II cells in high yield and purity. Am. Rev. Respir. Dis. 134: 141-145, 1986.
8. Dobbs, L. G., R. J. Mason, M. C. Williams, B. J. Benson, and K. Sueishi. Secretion of surfactant by primary cultures of alveolar type II cells isolated from rats. Biochim. Biophys. Acta 713: 118-127, 1982.
9. Dobbs, L. G., M. Pian, S. Dumars, M. Maglio, and L. Allen. Maintenance of the differentiated type II cell phenotype by culture with an apical air surface. Am. J. Physiol. 273 (Lung Cell. Mol. Physiol. 17): L347-L354, 1997.
10. Dobbs, L. G., M. C. Williams, and A. E. Brandt. Changes in biochemical characteristics and pattern of lectin binding of alveolar type II cells with time in culture. Biochim. Biophys. Acta 846: 155-156, 1985.
11. Dobbs, L. G., M. C. Williams, and R. Gonzalez. Monoclonal antibodies specific to apical surfaces of rat alveolar type I cells bind to surfaces of cultured, but not freshly isolated, type II cells. Biochim. Biophys. Acta 970: 146-156, 1988.
12. 2. Exp. Mol. Pathol. 22: 142-150, 1975.
13. Gardner, D. G., H. R. Wirtz, and L. G. Dobbs. Stretch-dependent regulation of atrial peptide synthesis and secretion in cultured atrial cardiocytes. Am. J. Physiol. 263 (Endocrinol. Metab. 26): E239-E244, 1992.
14. Goldspink, G., A. Scutt, P. T. Loughna, D. J. Wells, T. Jaenicke, and G. F. Gerlach. Gene expression in skeletal muscle in response to stretch and force generation. Am. J. Physiol. 262 (Regulatory Integrative Comp. Physiol. 31): R356-R363, 1992.
15. Goodman, B. E., and E. D. Crandall. Dome formation in primary cultured monolayers of alveolar epithelial cells. Am. J. Physiol. 243 (Cell Physiol. 12): C96-C100, 1982.
16. Hanlon, N. J., T. Collins, M. A. Gimbrone, and N. Resnick. Regulation of the endothelial PDGF-A gene by shear stress (Abstract). Circulation 90: 0468, 1994.
17. Hseih, H. J., N. Q. Li, and J. A. Frangos. Shear stress increases endothelial platelet-derived growth factor mRNA levels. Am. J. Physiol. 260 (Heart Circ. Physiol. 29): H642-H646, 1991.
18. Liley, H. G., R. T. White, R. G. Warr, B. J. Benson, S. Hawgood, and P. L. Ballard. Regulation of messenger RNAs for the hydrophobic surfactant proteins in human lung. J. Clin. Invest. 83: 1191-1197, 1989.
19. Mason, R. J., and L. G. Dobbs. Synthesis of phosphatidylcholine and phosphatidylglycerol by alveolar type II cells in primary culture. J. Biol. Chem. 255: 5101-5107, 1980.
20. Mason, R. J., L. G. Dobbs, R. D. Greenleaf, and M. C. Williams. Alveolar type II cells. Federation Proc. 36: 2697-2702, 1977.