Regulation of ROS-independent ERK signaling rescues replicative cellular senescence in ex vivo expanded human c-kit-positive cardiac progenitor cells

International Journal of Cardiology

Volumn 169, Issue 1, 2013, Pages 73-82

  Choi, Sung Hyun ^a   Jung, Seok Yun ^b   Yoo, So Young ^b   Yoo, Sae Mi ^a   Kim, Da Yeon ^b   Kang, Songhwa ^b   Baek, Sang Hong ^a   Kwon, Sang Mo ^b  

^a The Catholic University of Korea   (South Korea)

^b Pusan National University School of Medicine   (South Korea)

Author keywords

Cardiac progenitor cell; ERK; Peroxiredoxin; Reactive oxygen species; Replicative senescence

Indexed keywords

BETA GALACTOSIDASE; MITOGEN ACTIVATED PROTEIN KINASE; PEROXIREDOXIN 1; PEROXIREDOXIN 2; PROTEIN KINASE B; PROTEIN MDM2; PROTEIN P53; REACTIVE OXYGEN METABOLITE; STEM CELL FACTOR;

ARTICLE; CELL DIVISION; CELL EXPANSION; CELL PROLIFERATION; CELL SIZE; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; EX VIVO STUDY; HEART MUSCLE CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SENESCENCE; SIGNAL TRANSDUCTION; STEM CELL;

CARDIAC PROGENITOR CELL; ERK; PEROXIREDOXIN; REACTIVE OXYGEN SPECIES; REPLICATIVE SENESCENCE;

CELL AGING; CELL PROLIFERATION; CELLS, CULTURED; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; MAP KINASE SIGNALING SYSTEM; MYOCYTES, CARDIAC; PROTO-ONCOGENE PROTEINS C-KIT; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; STEM CELLS;

EID: 84886745975     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2013.08.076     Document Type: Article

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