Vitamin D intake in mid-pregnancy and child allergic disease - a prospective study in 44,825 Danish mother-child pairs

BMC Pregnancy and Childbirth

Volumn 13, Issue , 2013, Pages

  Maslova, Ekaterina ^a   Hansen, Susanne ^a   Jensen, Camilla B ^b   Thorne Lyman, Andrew L ^c   Strøm, Marin ^a   Olsen, Sjurdur F ^a,d  

^a STATENS SERUM INSTITUT   (Denmark)

^b The Capital Region   (Denmark)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Allergic rhinitis; Asthma; Cohort; Pregnancy; Vitamin D

Indexed keywords

VITAMIN D;

ADULT; ALLERGIC RHINITIS; ARTICLE; ASTHMA; CALORIC INTAKE; CHILD; CHILDHOOD DISEASE; COHORT ANALYSIS; DENMARK; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; FOOD FREQUENCY QUESTIONNAIRE; HUMAN; LONGITUDINAL STUDY; MALE; MATERNAL NUTRITION; OUTCOME ASSESSMENT; PRESCHOOL CHILD; PROSPECTIVE STUDY; SCHOOL CHILD; SELF REPORT; VITAMIN INTAKE; WHEEZING;

ADOLESCENT; ADULT; ASTHMA; CHILD; DENMARK; DIET; DIETARY SUPPLEMENTS; FEMALE; HUMANS; INFANT; LONGITUDINAL STUDIES; PREGNANCY; PREGNANCY TRIMESTER, SECOND; PRENATAL EXPOSURE DELAYED EFFECTS; PREVALENCE; PROSPECTIVE STUDIES; QUESTIONNAIRES; REGISTRIES; RHINITIS, ALLERGIC, PERENNIAL; VITAMIN D; VITAMINS; YOUNG ADULT;

EID: 84886744317     PISSN: None     EISSN: 14712393     Source Type: Journal    
DOI: 10.1186/1471-2393-13-199     Document Type: Article

References (75)

1. Beach RS, Gershwin ME, Hurley LS. Gestational zinc deprivation in mice: persistence of immunodeficiency for three generations. Science 1982, 218(4571):469-471. 10.1126/science.7123244, 7123244.
2. Calder PC, Yaqoob P. The level of protein and type of fat in the diet of pregnant rats both affect lymphocyte function in offspring. Nutr Res 2000, 45:333-344.
3. Mannino DM, Homa DM, Akinbami LJ, Moorman JE, Gwynn C, Redd SC. Surveillance for asthma-United States, 1980-1999. MMWR Surveill Summ 2002, 51(1):1-13.
4. Litonjua AA, Weiss ST. Is vitamin D deficiency to blame for the asthma epidemic?. J Allergy Clin Immunol 2007, 120(5):1031-1035. 10.1016/j.jaci.2007.08.028, 17919705.
5. Lamberg-Allardt C. Vitamin D in foods and as supplements. Prog Biophys Mol Biol 2006, 92(1):33-38. 10.1016/j.pbiomolbio.2006.02.017, 16618499.
6. Jacobsen R, Abrahamsen B, Bauerek M, Holst C, Jensen CB, Knop J, Raymond K, Rasmussen LB, Stougaard M, Sorensen TI, et al. The influence of early exposure to vitamin D for development of diseases later in life. BMC public health 2013, 13:515. 10.1186/1471-2458-13-515, 3672018, 23714352.
7. Holick MF. High prevalence of vitamin D inadequacy and implications for health. Mayo Clin Proc 2006, 81(3):353-373. 10.4065/81.3.353, 16529140.
8. Lee JM, Smith JR, Philipp BL, Chen TC, Mathieu J, Holick MF. Vitamin D deficiency in a healthy group of mothers and newborn infants. Clin Pediatr 2007, 46(1):42-44.
9. Lu Z, Chen TC, Zhang A, Persons KS, Kohn N, Berkowitz R, Martinello S, Holick MF. An evaluation of the vitamin D3 content in fish: Is the vitamin D content adequate to satisfy the dietary requirement for vitamin D?. J Steroid Biochem Mol Biol 2007, 103(3-5):642-644. 2698592, 17267210.
10. Glerup H, Mikkelsen K, Poulsen L, Hass E, Overbeck S, Thomsen J, Charles P, Eriksen EF. Commonly recommended daily intake of vitamin D is not sufficient if sunlight exposure is limited. J intern Med 2000, 247(2):260-268. 10.1046/j.1365-2796.2000.00595.x, 10692090.
11. Jensen CB, Thorne-Lyman A, Hansen LV, Strøm M, Nielsen NO, Cohen A, Olsen SF. Development and validation of a vitamin D status prediction model in Danish pregnant women: A study of the Danish National Birth Cohort. PloS one 2012, 8:e53059.
12. Norman AW. From vitamin D to hormone D: fundamentals of the vitamin D endocrine system essential for good health. Am J Clin Nutr 2008, 88(2):491S-499S.
13. Gregori S, Casorati M, Amuchastegui S, Smiroldo S, Davalli AM, Adorini L. Regulatory T cells induced by 1 alpha,25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance. J Immunol 2001, 167(4):1945-1953.
14. Gregori S, Giarratana N, Smiroldo S, Uskokovic M, Adorini L. A 1alpha,25-dihydroxyvitamin D(3) analog enhances regulatory T-cells and arrests autoimmune diabetes in NOD mice. Diabetes 2002, 51(5):1367-1374. 10.2337/diabetes.51.5.1367, 11978632.
15. Provvedini DM, Tsoukas CD, Deftos LJ, Manolagas SC. 1,25-dihydroxyvitamin D3 receptors in human leukocytes. Science 1983, 221:1181-1183. 10.1126/science.6310748, 6310748.
16. van Etten E, Mathieu C. Immunoregulation by 1,25-dihydroxyvitamin D3: basic concepts. J Steroid Biochem Mol Biol 2005, 97(1-2):93-101.
17. Wang TT, Nestel FP, Bourdeau V, Nagai Y, Wang Q, Liao J, Tavera-Mendoza L, Lin R, Hanrahan JW, Mader S, et al. Cutting edge: 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression. J Immunol 2004, 173(5):2909-2912.
18. Thomas SD, Fudge AN, Whiting M, Coates PS. The correlation between third-trimester maternal and newborn-serum 25-hydroxy-vitamin D in a selected South Australian group of newborn samples. BMJ Open 2011, 1(2):e000236. 10.1136/bmjopen-2011-000236, 3191602, 22021888.
19. Camargo CA, Rifas-Shiman SL, Litonjua AA, Rich-Edwards JW, Weiss ST, Gold DR, Kleinman K, Gillman MW. Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of age. Am J Clin Nutr 2007, 85(3):788-795.
20. Devereux G, Litonjua AA, Turner SW, Craig LC, McNeill G, Martindale S, Helms PJ, Seaton A, Weiss ST. Maternal vitamin D intake during pregnancy and early childhood wheezing. Am J Clin Nutr 2007, 85(3):853-859.
21. Miyake Y, Sasaki S, Tanaka K, Hirota Y. Dairy food, calcium and vitamin D intake in pregnancy, and wheeze and eczema in infants. Eur Respir J 2010, 35(6):1228-1234. 10.1183/09031936.00100609, 19840962.
22. Pike KC, Inskip HM, Robinson S, Lucas JS, Cooper C, Harvey NC, Godfrey KM, Roberts G, the Southampton Women's Survey Study G Maternal late-pregnancy serum 25-hydroxyvitamin D in relation to childhood wheeze and atopic outcomes. Thorax 2012, 67(11):950-956. 10.1136/thoraxjnl-2012-201888, 3679514, 22707522, the Southampton Women's Survey Study G.
23. Camargo CA, Ingham T, Wickens K, Thadhani R, Silvers KM, Epton MJ, Town GI, Pattemore PK, Espinola JA, Crane J, et al. Cord-blood 25-hydroxyvitamin D levels and risk of respiratory infection, wheezing, and asthma. Pediatrics 2011, 127(1):e180-e187. 10.1542/peds.2010-0442, 21187313.
24. Morales E, Romieu I, Guerra S, Ballester F, Rebagliato M, Vioque J, Tardon A, Rodriguez Delhi C, Arranz L, Torrent M, et al. Maternal vitamin D status in pregnancy and risk of lower respiratory tract infections, wheezing, and asthma in offspring. Epidemiology 2012, 23(1):64-71. 10.1097/EDE.0b013e31823a44d3, 22082994.
25. Jones AP, Palmer D, Zhang G, Prescott SL. Cord blood 25-hydroxyvitamin d3 and allergic disease during infancy. Pediatrics 2012, 130(5):e1128-e1135. 10.1542/peds.2012-1172, 23090338.
26. Gale CR, Robinson SM, Harvey NC, Javaid MK, Jiang B, Martyn CN, Godfrey KM, Cooper C, Princess Anne Hospital Study G Maternal vitamin D status during pregnancy and child outcomes. Eur J Clin Nutr 2008, 62(1):68-77. 10.1038/sj.ejcn.1602680, 2629513, 17311057, Princess Anne Hospital Study G.
27. Cremers E, Thijs C, Penders J, Jansen E, Mommers M. Maternal and child's vitamin D supplement use and vitamin D level in relation to childhood lung function: the KOALA Birth Cohort Study. Thorax 2011, 66(6):474-480. 10.1136/thx.2010.151985, 21422038.
28. Erkkola M, Kaila M, Nwaru BI, Kronberg-Kippila C, Ahonen S, Nevalainen J, Veijola R, Pekkanen J, Ilonen J, Simell O, et al. Maternal vitamin D intake during pregnancy is inversely associated with asthma and allergic rhinitis in 5-year-old children. Clin Exp Allergy 2009, 39(6):875-882. 10.1111/j.1365-2222.2009.03234.x, 19522996.
29. Mikkelsen TB, Osler M, Olsen SF. Validity of protein, retinol, folic acid and n-3 fatty acid intakes estimated from the food-frequency questionnaire used in the Danish National Birth Cohort. Public Health Nutr 2005, 9(6):771-778.
30. Olsen SF, Mikkelsen TB, Knudsen VK, Orozova-Bekkevold I, Halldórsson TI, Strøm M, Osterdal ML. Data collected on maternal dietary exposures in the Danish National Birth Cohort. Paediatr Perinat Epidemiol 2007, 21(1):76-86. 10.1111/j.1365-3016.2007.00777.x, 17239183.
31. Willett WC. Nutritional Epidemiology 1998, New York, USA: Oxford University Press, 2.
32. Brantsaeter AL, Haugen M, Hagve TA, Aksnes L, Rasmussen SE, Julshamn K, Alexander J, Meltzer HM. Self-reported dietary supplement use is confirmed by biological markers in the Norwegian Mother and Child Cohort Study (MoBa). Ann Nutr Metab 2007, 51(2):146-154. 10.1159/000103275, 17536192.
33. Asher MI, Keil U, Anderson HR, Beasley R, Crane J, Martinez F, Mitchell A, Pearce N, Sibbald B, Stewart AW, et al. International study of asthma and allergies in childhood (ISAAC): rationale and methods. Eur Respir J 1995, 8:483-491. 10.1183/09031936.95.08030483, 7789502.
34. Moth G, Vedsted P, Schiøtz PO. National registry diagnoses agree with medical records on hospitalized asthmatic children. Acta Paediatr 2007, 96:1470-1473. 10.1111/j.1651-2227.2007.00460.x, 17727688.
35. Forskningsdatabaser Databeredskab i Danmarks Statistik. (In Danish) 2002, Copenhagen, Denmark: Danmarks Statistik, Forskningsdatabaser.
36. Moth G, Vedsted P, Schiøtz PO. Identification of asthmatic children using prescription data and diagnosis. Eur J Clin Pharmacol 2007, 63:605-611. 10.1007/s00228-007-0286-4, 17387463.
37. Litonjua AA. Dietary factors and the development of asthma. Immunol allergy Clin North Am 2008, 28(3):603-629. ix, 10.1016/j.iac.2008.03.005, 2536613, 18572110.
38. Institute of Medicine of the National Academies Dietary Reference Intakes for Calcium and Vitamin D 2010, Washington, DC, USA: The National Academies Press, Institute of Medicine of the National Academies.
39. Nordic Council of Ministers Nordic Nutrition Recommendations 2012. Summary, principles, and use. 5th edition 2013, Copenhagen, Denmark: Nordic Council of Ministers, Nordic Council of Ministers.
40. Durrleman S, Simon R. Flexible regression models with cubic splines. Stat Med 1989, 8(5):551-561. 10.1002/sim.4780080504, 2657958.
41. Skov T, Deddens J, Petersen MR, Endahl L. Prevalence proportion ratios: estimation and hypothesis testing. Int J Epidemiol 1998, 27(1):91-95. 10.1093/ije/27.1.91, 9563700.
42. Wacholder S. Binomial regression in GLIM: estimating risk ratios and risk differences. Am J Epidemiol 1986, 123(1):174-184.
43. Zou G. A modified poisson regression approach to prospective studies with binary data. Am J Epidemiol 2004, 159(7):702-706. 10.1093/aje/kwh090, 15033648.
44. Mantel N. Chi-square tests with one degree of freedom: extensions of the Mantel-Haenszel procedure. J Am Stat Assoc 1963, 58:69O-70O.
45. Bel EH. Clinical phenotypes of asthma. Curr Opin Pulm Med 2004, 10(1):44-50. 10.1097/00063198-200401000-00008, 14749605.
46. Jensen CB, Petersen SB, Granstrom C, Maslova E, Molgaard C, Olsen SF. Sources and determinants of vitamin D intake in Danish pregnant women. Nutrients 2012, 4(4):259-272. 3347007, 22606369.
47. Hollis BW, Wagner CL. Nutritional vitamin D status during pregnancy: reasons for concern. CMAJ 2006, 174(9):1287-1290. 10.1503/cmaj.060149, 1435950, 16636329.
48. Brot C, Jorgensen NR, Sorensen OH. The influence of smoking on vitamin D status and calcium metabolism. Eur J Clin Nutr 1999, 53(12):920-926. 10.1038/sj.ejcn.1600870, 10602348.
49. Gram J, Junker P, Nielsen HK, Bollerslev J. Effects of short-term treatment with prednisolone and calcitriol on bone and mineral metabolism in normal men. Bone 1998, 23(3):297-302. 10.1016/S8756-3282(98)00097-0, 9737353.
50. Hartwell D, Riis BJ, Christiansen C. Comparison of vitamin D metabolism in early healthy and late osteoporotic postmenopausal women. Calcif Tissue Int 1990, 47(6):332-337. 10.1007/BF02555883, 2292078.
51. Lester E, Skinner RK, Foo AY, Lund B, Sorensen OH. Serum 25-hydroxyvitamin D levels and vitamin D intake in healthy young adults in Britain and Denmark. Scand J Clin Lab Invest 1980, 40(2):145-150. 10.3109/00365518009093017, 7256182.
52. Lund B, Sorensen OH. Measurement of 25-hydroxyvitamin D in serum and its relation to sunshine, age and vitamin D intake in the Danish population. Scand J Clin Lab Invest 1979, 39(1):23-30. 10.3109/00365517909104935, 523951.
53. Tjellesen L, Christiansen C. Vitamin D metabolites in normal subjects during one year. A longitudinal study. Scand J Clin Lab Invest 1983, 43(1):85-89. 10.3109/00365518309168226, 6604936.
54. Osler M, Schroll M. A dietary study of the elderly in the City of Roskilde 1988/1989 (II). A nutritional risk assessment. Dan Medl Bull 1991, 38(5):410-413.
55. Wagner CL, Taylor SN, Dawodu A, Johnson DD, Hollis BW. Vitamin D and its role during pregnancy in attaining optimal health of mother and fetus. Nutrients 2012, 4(3):208-230. 3347028, 22666547.
56. Hollis BW, Wagner CL. Vitamin D and Pregnancy: Skeletal Effects, Nonskeletal Effects, and Birth Outcomes. Calcified Tissue Int 2013, 92(2):128-139.
57. Wortsman J, Matsuoka LY, Chen TC, Lu Z, Holick MF. Decreased bioavailability of vitamin D in obesity. Am J Clin Nutr 2000, 72(3):690-693.
58. Robinson DS. Regulatory T cells and asthma. Clin Exp Allergy 2009, 39(9):1314-1323. 10.1111/j.1365-2222.2009.03301.x, 19538496.
59. Parronchi P, Manetti R, Simonelli C, Rugiu FS, Piccinni MP, Maggi E, Romagnani S. Cytokine production by allergen (Der pI)-specific CD4+ T cell clones derived from a patient with severe atopic disease. Int J Clin Lab Res 1991, 21(2):186-189.
60. Wierenga EA, Snoek M, de Groot C, Chretien I, Bos JD, Jansen HM, Kapsenberg ML. Evidence for compartmentalization of functional subsets of CD2+ T lymphocytes in atopic patients. J Immunol 1990, 144(12):4651-4656.
61. Akdis M, Verhagen J, Taylor A, Karamloo F, Karagiannidis C, Crameri R, Thunberg S, Deniz G, Valenta R, Fiebig H, et al. Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells. J Exp Med 2004, 199(11):1567-1575. 10.1084/jem.20032058, 2211782, 15173208.
62. Grindebacke H, Wing K, Andersson AC, Suri-Payer E, Rak S, Rudin A. Defective suppression of Th2 cytokines by CD4CD25 regulatory T cells in birch allergics during birch pollen season. Clin Exp Allergy 2004, 34(9):1364-1372. 10.1111/j.1365-2222.2004.02067.x, 15347368.
63. Meehan MA, Kerman RH, Lemire JM. 1,25-Dihydroxyvitamin D3 enhances the generation of nonspecific suppressor cells while inhibiting the induction of cytotoxic cells in a human MLR. Cell Immunol 1992, 140(2):400-409. 10.1016/0008-8749(92)90206-5, 1531943.
64. Xystrakis E, Kusumakar S, Boswell S, Peek E, Urry Z, Richards DF, Adikibi T, Pridgeon C, Dallman M, Loke TK, et al. Reversing the defective induction of IL-10-secreting regulatory T cells in glucocorticoid-resistant asthma patients. J Clin Invest 2006, 116(1):146-155. 1307558, 16341266.
65. Bhalla AK, Amento EP, Serog B, Glimcher LH. 1,25-Dihydroxyvitamin D3 inhibits antigen-induced T cell activation. J Immunol 1984, 133(4):1748-1754.
66. Milovanovic M, Heine G, Hallatschek W, Opitz B, Radbruch A, Worm M. Vitamin D receptor binds to the epsilon germline gene promoter and exhibits transrepressive activity. J Allergy Clin Immunol 2010, 126(5):1016-1023. 1023 e1011-1014, 10.1016/j.jaci.2010.08.020, 20926124.
67. Song Y, Qi H, Wu C. Effect of 1,25-(OH)2D3 (a vitamin D analogue) on passively sensitized human airway smooth muscle cells. Respirology 2007, 12(4):486-494. 10.1111/j.1440-1843.2007.01099.x, 17587413.
68. Banerjee A, Damera G, Bhandare R, Gu S, Lopez-Boado Y, Panettieri R, Tliba O. Vitamin D and glucocorticoids differentially modulate chemokine expression in human airway smooth muscle cells. Br J Pharmacol 2008, 155(1):84-92. 10.1038/bjp.2008.232, 2440089, 18552877.
69. Cantorna MT, Zhu Y, Froicu M, Wittke A. Vitamin D status, 1,25-dihydroxyvitamin D3, and the immune system. Am J Clin Nutr 2004, 80(6 Suppl):1717S-1720S.
70. Boonstra A, Barrat FJ, Crain C, Heath VL, Savelkoul HF, O'Garra A. 1alpha,25-Dihydroxyvitamin d3 has a direct effect on naive CD4(+) T cells to enhance the development of Th2 cells. J Immunol 2001, 167(9):4974-4980.
71. Matheu V, Back O, Mondoc E, Issazadeh-Navikas S. Dual effects of vitamin D-induced alteration of TH1/TH2 cytokine expression: enhancing IgE production and decreasing airway eosinophilia in murine allergic airway disease. J Allergy Clin Immunol 2003, 112(3):585-592. 10.1016/S0091-6749(03)01855-4, 13679819.
72. Pichler J, Gerstmayr M, Szepfalusi Z, Urbanek R, Peterlik M, Willheim M. 1 alpha,25(OH)2D3 inhibits not only Th1 but also Th2 differentiation in human cord blood T cells. Pediatr Res 2002, 52(1):12-18.
73. Jensen Østergaard A, Lauge Nielsen G, Ehrenstei V. Validity of asthma diagnoses in the Danish National Registry of Patients, including an assessment of impact of misclassification on risk estimates in an actual datase. Clin Epi 2010, 2:67-72.
74. Hansen S, Strom M, Maslova E, Mortensen EL, Granstrom C, Olsen SF. A comparison of three methods to measure asthma in epidemiologic studies: results from the danish national birth cohort. PloS One 2012, 7(5):e36328. 10.1371/journal.pone.0036328, 3350521, 22606255.
75. Heaney RP. Health is better at serum 25(OH)D above 30ng/mL. J steroid Biochem Mol Biol 2013, 136:224-228.