Mechanisms of interaction of acetaminophen metabolites in terms of hepatotoxicity

Current Issues in Pharmacy and Medical Sciences

Volumn 26, Issue 2, 2013, Pages 206-210

  Topoła, Milena ^a   Podawacz, Magdalena ^a   Śliwińska Mossoń, Mariola ^a   Sajewicz, Waldemar ^a   Milnerowicz, Halina ^a  

^a WROCLAW MEDICAL UNIVERSITY   (Poland)

Author keywords

Acetaminophen; Covalent modification of proteins; Cytochrome P 450; Hepatotoxicity

Indexed keywords

1,4 BENZOQUINONE; 3 THIOMETHYLAMINOPHEN; 4 AMINOPHENOL; ACETYLCYSTEINE; DRUG METABOLITE; LIPID; METACETAMOL; N ACETYL 1,4 BENZOQUINONE IMINE; PARACETAMOL; PARACETAMOL GLUCURONIDE; UNCLASSIFIED DRUG;

CELL DEATH; CELL NUCLEUS; DRUG HALF LIFE; DRUG MECHANISM; DRUG METABOLISM; DRUG TRANSFORMATION; HUMAN; LIPID PEROXIDATION; LIVER CELL; LIVER TOXICITY; MITOCHONDRIAL PERMEABILITY; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; REVIEW;

EID: 84886740400     PISSN: 2084980X     EISSN: None     Source Type: Journal    
DOI: 10.12923/j.2084-980X/26.2/a.19     Document Type: Review

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