The anti-lung cancer activities of steroidal saponins of P. polyphylla smith var. chinensis (Franch.) hara through enhanced immunostimulation in experimental lewis tumor-bearing C57BL/6 mice and induction of apoptosis in the A549 cell line

Molecules

Volumn 18, Issue 10, 2013, Pages 12916-12936

  Li, Yu ^a,b,c   Gu, Jun Fei ^b   Zou, Xi ^a   Wu, Jian ^a   Zhang, Ming Hua ^b   Jiang, Jun ^b   Qin, Dong ^b   Zhou, Jin Yong ^a   Liu, Bao Xin Zi ^a   Zhu, Yun Tao ^d   Jia, Xiao Bin ^b   Feng, Liang ^b   Wang, Rui Ping ^a  

^a AFFILIATED HOSPITAL OF NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b KEY LABORATORY OF NEW DRUG DELIVERY SYSTEM OF CHINESE MATERIA MEDICA   (China)

^c THE FIRST AFFILIATED HOSPITAL OF GUANGXI UNIVERSITY OF CHINESE MEDICINE   (China)

^d NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Apoptosis; Immunostimulation; Inflammation; P. polyphylla Smith var. chinensis (Franch.) Hara; Steroidal saponins

Indexed keywords

ANTINEOPLASTIC AGENT; HERBACEOUS AGENT; IMMUNOLOGIC FACTOR; REACTIVE OXYGEN METABOLITE; SAPONIN;

ANGIOSPERM; ANIMAL; APOPTOSIS; ARTICLE; C57BL MOUSE; CANCER TRANSPLANTATION; CELL SURVIVAL; CHEMISTRY; DRUG EFFECT; DRUG SCREENING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; ISOLATION AND PURIFICATION; LEWIS CARCINOMA; MALE; METABOLISM; MOUSE; OXIDATIVE STRESS; PATHOLOGY; TANDEM MASS SPECTROMETRY; TUMOR CELL LINE; TUMOR VOLUME; CARCINOMA, LEWIS LUNG; DRUG EFFECTS;

ANGIOSPERMS; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CARCINOMA, LEWIS LUNG; CELL LINE, TUMOR; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG SCREENING ASSAYS, ANTITUMOR; DRUGS, CHINESE HERBAL; HUMANS; IMMUNOLOGIC FACTORS; MALE; MICE; MICE, INBRED C57BL; NEOPLASM TRANSPLANTATION; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SAPONINS; TANDEM MASS SPECTROMETRY; TUMOR BURDEN;

EID: 84886616105     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules181012916     Document Type: Article

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