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Volumn 319, Issue 19, 2013, Pages 3000-3009

Epithelial-to-mesenchymal transition in fibrosis: Collagen type I expression is highly upregulated after EMT, but does not contribute to collagen deposition

Author keywords

Collagen deposition; Epithelial cells; Epithelial to mesenchymal transition; Fibrosis; Myofibroblasts

Indexed keywords

COLLAGEN TYPE 1; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84886600453     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2013.07.014     Document Type: Article
Times cited : (56)

References (38)
  • 1
    • 33847350691 scopus 로고    scopus 로고
    • Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases
    • Wynn T.A. Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases. J. Clin. Invest. 2007, 117:524-529.
    • (2007) J. Clin. Invest. , vol.117 , pp. 524-529
    • Wynn, T.A.1
  • 2
    • 79955979410 scopus 로고    scopus 로고
    • Fibroblasts and myofibroblasts in renal fibrosis
    • Meran S., Steadman R. Fibroblasts and myofibroblasts in renal fibrosis. Int. J. Exp. Pathol. 2011, 92:158-167.
    • (2011) Int. J. Exp. Pathol. , vol.92 , pp. 158-167
    • Meran, S.1    Steadman, R.2
  • 5
    • 79960381007 scopus 로고    scopus 로고
    • Integrating mechanisms of pulmonary fibrosis
    • Wynn T.A. Integrating mechanisms of pulmonary fibrosis. J. Exp. Med. 2011, 208:1339-1350.
    • (2011) J. Exp. Med. , vol.208 , pp. 1339-1350
    • Wynn, T.A.1
  • 6
    • 69949124749 scopus 로고    scopus 로고
    • Direct contribution of epithelium to organ fibrosis: epithelial-mesenchymal transition
    • Guarino M., Tosoni A., Nebuloni M. Direct contribution of epithelium to organ fibrosis: epithelial-mesenchymal transition. Hum. Pathol. 2009, 40:1365-1376.
    • (2009) Hum. Pathol. , vol.40 , pp. 1365-1376
    • Guarino, M.1    Tosoni, A.2    Nebuloni, M.3
  • 7
    • 80052851503 scopus 로고    scopus 로고
    • Role of endothelial-mesenchymal transition (EndoMT) in the pathogenesis of fibrotic disorders
    • Piera-Velazquez S., Li Z., Jimenez S.A. Role of endothelial-mesenchymal transition (EndoMT) in the pathogenesis of fibrotic disorders. Am. J. Pathol. 2011, 179:1074-1080.
    • (2011) Am. J. Pathol. , vol.179 , pp. 1074-1080
    • Piera-Velazquez, S.1    Li, Z.2    Jimenez, S.A.3
  • 8
    • 73549092294 scopus 로고    scopus 로고
    • Endothelial-myofibroblast transition contributes to the early development of diabetic renal interstitial fibrosis in streptozotocin-induced diabetic mice
    • Li J., Qu X., Bertram J.F. Endothelial-myofibroblast transition contributes to the early development of diabetic renal interstitial fibrosis in streptozotocin-induced diabetic mice. Am. J. Pathol. 2009, 175:1380-1388.
    • (2009) Am. J. Pathol. , vol.175 , pp. 1380-1388
    • Li, J.1    Qu, X.2    Bertram, J.F.3
  • 10
    • 77953769774 scopus 로고    scopus 로고
    • Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis
    • Flier S.N., Tanjore H., Kokkotou E.G., Sugimoto H., Zeisberg M., Kalluri R. Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis. J. Biol. Chem. 2010, 285:20202-20212.
    • (2010) J. Biol. Chem. , vol.285 , pp. 20202-20212
    • Flier, S.N.1    Tanjore, H.2    Kokkotou, E.G.3    Sugimoto, H.4    Zeisberg, M.5    Kalluri, R.6
  • 15
    • 34548145815 scopus 로고    scopus 로고
    • Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition
    • Zeisberg M., Yang C., Martino M., Duncan M.B., Rieder F., Tanjore H., Kalluri R. Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition. J. Biol. Chem. 2007, 282:23337-23347.
    • (2007) J. Biol. Chem. , vol.282 , pp. 23337-23347
    • Zeisberg, M.1    Yang, C.2    Martino, M.3    Duncan, M.B.4    Rieder, F.5    Tanjore, H.6    Kalluri, R.7
  • 16
    • 79958779687 scopus 로고    scopus 로고
    • Scar wars: mapping the fate of epithelial-mesenchymal-myofibroblast transition
    • Quaggin S.E., Kapus A. Scar wars: mapping the fate of epithelial-mesenchymal-myofibroblast transition. Kidney Int. 2011, 80:41-50.
    • (2011) Kidney Int. , vol.80 , pp. 41-50
    • Quaggin, S.E.1    Kapus, A.2
  • 17
    • 79551521517 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition (EMT) in kidney fibrosis: fact or fantasy?
    • Kriz W., Kaissling B., Le H.M. Epithelial-mesenchymal transition (EMT) in kidney fibrosis: fact or fantasy?. J. Clin. Invest. 2011, 121:468-474.
    • (2011) J. Clin. Invest. , vol.121 , pp. 468-474
    • Kriz, W.1    Kaissling, B.2    Le, H.M.3
  • 18
    • 77950612565 scopus 로고    scopus 로고
    • The epithelial-to-mesenchymal transition in liver fibrosis: here today, gone tomorrow?
    • Wells R.G. The epithelial-to-mesenchymal transition in liver fibrosis: here today, gone tomorrow?. Hepatology 2010, 51:737-740.
    • (2010) Hepatology , vol.51 , pp. 737-740
    • Wells, R.G.1
  • 19
    • 79955955054 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in renal fibrosis-evidence for and against
    • Fragiadaki M., Mason R.M. Epithelial-mesenchymal transition in renal fibrosis-evidence for and against. Int. J. Exp. Pathol. 2011, 92:143-150.
    • (2011) Int. J. Exp. Pathol. , vol.92 , pp. 143-150
    • Fragiadaki, M.1    Mason, R.M.2
  • 20
    • 84857111725 scopus 로고    scopus 로고
    • The origin of interstitial myofibroblasts in chronic kidney disease
    • Grgic I., Duffield J.S., Humphreys B.D. The origin of interstitial myofibroblasts in chronic kidney disease. Pediatr. Nephrol. 2012, 27:183-193.
    • (2012) Pediatr. Nephrol. , vol.27 , pp. 183-193
    • Grgic, I.1    Duffield, J.S.2    Humphreys, B.D.3
  • 21
    • 79551479332 scopus 로고    scopus 로고
    • Renal interstitial fibrosis: a critical evaluation of the origin of myofibroblasts
    • Barnes J.L., Glass W.F. Renal interstitial fibrosis: a critical evaluation of the origin of myofibroblasts. Contrib. Nephrol. 2011, 169:73-93.
    • (2011) Contrib. Nephrol. , vol.169 , pp. 73-93
    • Barnes, J.L.1    Glass, W.F.2
  • 23
    • 77950565076 scopus 로고    scopus 로고
    • Autophagy is a component of epithelial cell fate in obstructive uropathy
    • Li L., Zepeda-Orozco D., Black R., Lin F. Autophagy is a component of epithelial cell fate in obstructive uropathy. Am. J. Pathol. 2010, 176:1767-1778.
    • (2010) Am. J. Pathol. , vol.176 , pp. 1767-1778
    • Li, L.1    Zepeda-Orozco, D.2    Black, R.3    Lin, F.4
  • 26
  • 28
    • 27544515448 scopus 로고    scopus 로고
    • Origin of interstitial fibroblasts in an accelerated model of angiotensin II-induced renal fibrosis
    • Faulkner J.L., Szcykalski L.M., Springer F., Barnes J.L. Origin of interstitial fibroblasts in an accelerated model of angiotensin II-induced renal fibrosis. Am. J. Pathol. 2005, 167:1193-1205.
    • (2005) Am. J. Pathol. , vol.167 , pp. 1193-1205
    • Faulkner, J.L.1    Szcykalski, L.M.2    Springer, F.3    Barnes, J.L.4
  • 30
    • 57149113728 scopus 로고    scopus 로고
    • Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney
    • Lin S.L., Kisseleva T., Brenner D.A., Duffield J.S. Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney. Am. J. Pathol. 2008, 173:1617-1627.
    • (2008) Am. J. Pathol. , vol.173 , pp. 1617-1627
    • Lin, S.L.1    Kisseleva, T.2    Brenner, D.A.3    Duffield, J.S.4
  • 31
    • 73949090678 scopus 로고    scopus 로고
    • TGF-beta1 induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells is enhanced by IL-1beta but not abrogated by corticosteroids
    • Doerner A.M., Zuraw B.L. TGF-beta1 induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells is enhanced by IL-1beta but not abrogated by corticosteroids. Respir. Res. 2009, 10:100.
    • (2009) Respir. Res. , vol.10 , pp. 100
    • Doerner, A.M.1    Zuraw, B.L.2
  • 32
    • 0032842887 scopus 로고    scopus 로고
    • Transforming growth factor-beta regulates tubular epithelial-myofibroblast transdifferentiation in vitro
    • Fan J.M., Ng Y.Y., Hill P.A., Nikolic-Paterson D.J., Mu W., Atkins R.C., Lan H.Y. Transforming growth factor-beta regulates tubular epithelial-myofibroblast transdifferentiation in vitro. Kidney Int. 1999, 56:1455-1467.
    • (1999) Kidney Int. , vol.56 , pp. 1455-1467
    • Fan, J.M.1    Ng, Y.Y.2    Hill, P.A.3    Nikolic-Paterson, D.J.4    Mu, W.5    Atkins, R.C.6    Lan, H.Y.7
  • 35
    • 0034785496 scopus 로고    scopus 로고
    • Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis
    • Yang J., Liu Y. Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis. Am. J. Pathol. 2001, 159:1465-1475.
    • (2001) Am. J. Pathol. , vol.159 , pp. 1465-1475
    • Yang, J.1    Liu, Y.2
  • 36
    • 33646858310 scopus 로고    scopus 로고
    • TGFbeta1 induces epithelial-mesenchymal transition, but not myofibroblast transdifferentiation of human kidney tubular epithelial cells in primary culture
    • Forino M., Torregrossa R., Ceol M., Murer L., Della V.M., Del P.D., D'Angelo A., Anglani F. TGFbeta1 induces epithelial-mesenchymal transition, but not myofibroblast transdifferentiation of human kidney tubular epithelial cells in primary culture. Int. J. Exp. Pathol. 2006, 87:197-208.
    • (2006) Int. J. Exp. Pathol. , vol.87 , pp. 197-208
    • Forino, M.1    Torregrossa, R.2    Ceol, M.3    Murer, L.4    Della, V.M.5    Del, P.D.6    D'Angelo, A.7    Anglani, F.8
  • 37
    • 0036014928 scopus 로고    scopus 로고
    • Smad7 inhibits fibrotic effect of TGF-Beta on renal tubular epithelial cells by blocking Smad2 activation
    • Li J.H., Zhu H.J., Huang X.R., Lai K.N., Johnson R.J., Lan H.Y. Smad7 inhibits fibrotic effect of TGF-Beta on renal tubular epithelial cells by blocking Smad2 activation. J. Am. Soc. Nephrol. 2002, 13:1464-1472.
    • (2002) J. Am. Soc. Nephrol. , vol.13 , pp. 1464-1472
    • Li, J.H.1    Zhu, H.J.2    Huang, X.R.3    Lai, K.N.4    Johnson, R.J.5    Lan, H.Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.