Chronic effect of erythromycin on substrate biodegradation kinetics of activated sludge

Biochemical Engineering Journal

Volumn 81, Issue , 2013, Pages 29-39

  Pala Ozkok, Ilke ^a   Orhon, Derin ^a,b  

^a ISTANBUL TECHNICAL UNIVERSITY   (Turkey)

^b The Science Academy   (Turkey)

Author keywords

Biodegradation; Chronic inhibition; Erythromycin; Kinetic parameters; Modeling; Waste water treatment

Indexed keywords

BIODEGRADATION KINETICS; ENDOGENOUS RESPIRATION; ERYTHROMYCIN; MACROLIDE ANTIBIOTICS; MICROBIAL ACTIVITIES; MICROBIAL COMMUNITIES; MICROBIAL METABOLISM; STEADY-STATE OPERATION;

BATCH REACTORS; BIODEGRADATION; DIGITAL STORAGE; GROWTH KINETICS; KINETIC PARAMETERS; KINETICS; METABOLISM; MICROORGANISMS; MODELS; OXYGEN; SUBSTRATES;

ANTIBIOTICS;

ERYTHROMYCIN; PEPTONE;

ACTIVATED SLUDGE; ARTICLE; BATCH REACTOR; BIODEGRADATION; BIOMASS; CALIBRATION; DEGRADATION KINETICS; HYDROLYSIS; MICROBIAL ACTIVITY; MICROBIAL COMMUNITY; MICROBIAL GROWTH; MICROBIAL METABOLISM; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; STEADY STATE; STOICHIOMETRY;

EID: 84886524055     PISSN: 1369703X     EISSN: 1873295X     Source Type: Journal    
DOI: 10.1016/j.bej.2013.10.002     Document Type: Article

References (54)

1. Wöhler F. On the artificial production of urea. Ann. Phys. Chem. 1828, 88(2):253-256.
2. Kümmerer K. Antibiotics in the aquatic environment - a review. Part I. Chemosphere 2009, 75:417-434.
3. Alonso A., Sanchez P., Martinez J.L. Environmental selection of antibiotic resistance genes. Environ. Microbiol. 2001, 3(1):1-9.
4. Golet E.M., Alder A.C., Giger W. Environmental exposure and risk assessment of fluoroquinolone antibacterial agents in wastewater and river water of the Glatt Valley Watershed, Switzerland. Environ. Sci. Technol. 2002, 36(17):3645-3651.
5. Göbel A., Thomsen A., McArdell C.S., Joss A., Giger W. Occurrence and sorption behavior of sulfonamides, macrolides, and trimethoprim in activated sludge treatment. Environ. Sci. Technol. 2005, 39(11):3981-3989.
6. Xu W.H., Zhang G., Li X.D., Zou S.C., Li P., Hu Z.H., Li J. Occurrence and elimination of antibiotics at four sewage treatment plants in the Pearl River Delta (PRD), South China. Water Res. 2007, 41(19):4526-4534.
7. Li B., Zhang T. Biodegradation and adsorption of antibiotics in the activated sludge process. Environ. Sci. Technol. 2010, 44:3468-3473.
8. Al-Ahmad A., Haiß A., Unger J., Brunswick-Tietze A., Wiethan J., Kümmerer K. Effects of a realistic mixture of antibiotics on resistant and nonresistant sewage sludge bacteria in laboratory-scale treatment plants. Arch. Environ. Contam. Toxicol. 2009, 57:264-273.
9. Tenson T., Lovmar M., Ehrenberg M. The mechanism of action of macrolides, lincosamides and streptogramin B reveals the nascent peptide exit path in the ribosome. J. Mol. Biol. 2003, 330(5):1005-1014.
10. Hirsch R., Ternes T., Haberer K., Kratz K-L. Occurrence of antibiotics in the aquatic environment. Sci. Total Environ. 1999, 225:109-118.
11. Giger W., Alder A.C., Golet E.M., Kohler H.P.E., McArdell C.S., Molnar E., Siegrist H., Suter M.J.F. Occurrence and fate of antibiotics as trace contaminants in wastewaters, sewage sludges, and surface waters. Chimia 2003, 57:485-491.
12. Alexy R., Sommer A., Lange F.T., Kümmerer K. Local use of antibiotics and their input and fate in a small sewage treatment plant - significance of balancing and analysis on a local scale vs. nationwide scale. Acta. Hydroch. Hydrob. 2006, 34:587-592.
13. Radjenovic J., Petrovic M., Barcelo D. Analysis of pharmaceuticals in wastewater and removal using a membrane bioreactor. Anal. Bioanal. Chem. 2007, 387:1365-1377.
14. Göbel A., McArdell C.S., Joss A., Siegrist H., Giger W. Fate of sulfonamides, macrolides, and trimethoprim in different wastewater treatment technologies. Sci. Total Environ. 2007, 372:361-371.
15. Louvet J.N., Giammarino C., Potier O., Pons M.N. Adverse effects of erythromycin on the structure and chemistry of activated sludge. Environ. Pollut. 2010, 158:688-693.
16. Orhon D., Artan N. Modelling of Activated Sludge Systems 1994, Technomic Publishing AG, Basel.
17. Mulchandani A., Luong J.H.T. Microbial inhibition kinetics revisited. Enzyme Microb. Technol. 1989, 11(2):66-73.
18. Ozkok I.P., Yazan T.K., Cokgor E.U., Insel G., Talinli I., Orhon D. Respirometric assessment of substrate binding by antibiotics in peptone biodegradation. J. Environ. Sci. Health A 2011, 46:1588-1597.
19. Insel G., Karahan O., Ozdemir S., Pala I., Katipoglu T., Ubay Cokgor E., Orhon D. Unified basis for the respirometric evaluation of inhibition for activated sludge. J. Environ. Sci. Health A 2006, 41:1763-1780.
20. Vanrolleghem P.A. Principles of respirometry in activated sludge wastewater treatment. Proceedings International Workshop on Recent Development in Respirometry for Wastewater Treatment Plant Monitoring and Control 2002, pp. 2/1-20.
21. Orhon D., Ubay Cokgor E., Insel G., Karahan O., Katipoglu T. Validity of monod kinetics at different sludge ages - peptone biodegradation under aerobic conditions. Bioresour. Technol. 2009, 100:5678-5686.
22. Orhon D., Sözen S. Fate and effect of xenobiotics on biodegradation processes: basis for respirometric appraisal. Environ. Technol. 2012, 33(13):1517-1522.
23. Pala-Ozkok I., Ubay-Cokgor E., Petek Cakar Z., Orhon D. Modeling acute inhibitory impact of erythromycin on substrate biodegradation of activated sludge under aerobic conditions. J. Chem. Technol. Biotechnol. 2013, 10.1002/jctb.4208.
24. Ekama G.A., Dold P.L., Marais G.V.R. Procedures for determining influent COD fractions and the maximum specific growth rate of heterotrophs in activated sludge systems. Water Sci. Technol. 1986, 18:91-114.
25. Henze M., Leslie Grady C.P., Gujer W., Marais G.V.R., Matsuo T. A general model for single-sludge wastewater treatment systems. Water Res. 1987, 21(5):505-515.
26. Insel G., Orhon D., Vanrolleghem P.A. Identification and modelling of aerobic hydrolysis mechanism-application of optimal experimental design. J. Chem. Technol. Biotechnol. 2003, 78:437-445.
27. Ciggin A.S., Orhon D., Capitani D., Miccheli A., Puccetti C., Majone M. Aerobic metabolism of mixed carbon sources in sequencing batch reactor under pulse and continuous feeding. Bioresour. Technol. 2013, 129:118-126.
28. ISO 8192 Water quality-test for inhibition of oxygen consumption by activated sludge 2007, International Standards Organization, Switzerland.
29. Sponza D.T., Celebi H. Removal of oxytetracycline (OTC) in a synthetic pharmaceutical wastewater by sequential anaerobic multichamber bed reactor (AMCBR)/completely stirred tank reactor (CSTR) system: biodegradation and inhibition kinetics. J. Chem. Technol. Biotechnol. 2012, 87(7):961-975.
30. Pala-Ozkok I., Rehman A., Yagci N., Ubay-Cokgor E., Jonas D., Orhon D. Characteristics of mixed microbial culture at different sludge ages: effect on variable kinetics for substrate utilization. Bioresour. Technol. 2012, 126:274-282.
31. Reichert P., Ruchti J., Simon W. AQUASIM 2.0 1998, Swiss Federal Institute for Environmental Science and Technology (EAWAG), CH-8600, Duebendorf, Switzerland.
32. Germirli Babuna F., Orhon D., Ubay Çokgör E., Insel G., Yaprakli B. Modelling of activated sludge for textile wastewaters. Water Sci. Technol. 1998, 38(4/5):9-17.
33. Gujer W., Henze M., Mino T., Loosdrecht M.v. Activated sludge model no. 3. Water Sci. Technol. 1999, 39(1):183-193.
34. Krishna C., van Loosdrecht M.C.M. Substrate flux into storage and growth in relation to activated sludge modeling. Water Res. 1999, 33:3149-3161.
35. Karahan O., van Loosdrecht M.C.M., Orhon D. Modification of activated sludge model no.3 considering direct growth on primary substrate. Water Sci. Technol. 2003, 47(11):219-225.
36. Orhon D., Ubay Çokgör E., Sözen S. Dual hydrolysis model of the slowly biodegradable substrate in activated sludge systems. Biotechnol. Tech. 1998, 12(10):737-741.
37. Ubay-Cokgor E., Insel G., Katipoglu T., Orhon D. Biodegradation kinetics of peptone and 2,6-dihydroxybenzoic acid by acclimated dual microbial culture. Bioresour. Technol. 2011, 102:567-575.
38. Çiǧgin A.S., Insel G., Majone M., Orhon D. Respirometric evaluation and modelling of acetate utilization in sequencing batch reactor under pulse and continuous feeding. Bioresour. Technol. 2012, 107:61-69.
39. Brun R., Reichert P., Künsch R.K. Practical identifiability analysis of large environmental simulation models. Water Resour. Res. 2001, 37:1015-1030.
40. Hocaoglu S.M., Insel G., Cokgor E.U., Orhon D. Effect of low dissolved oxygen on simultaneous nitrification and denitrification in a membrane bioreactor treating black water. Bioresour. Technol. 2011, 102(6):4333-4340.
41. ISO 6060 Water Quality-Determination of the Chemical Oxygen Demand 1986, International Standards Organization, Switzerland.
42. Standard Methods for the Examination of Water and Wastewater 2005, American Public Health Association/American Water Works Association/Water Environment Federation, Washington DC, U.S.A. 21st ed.
43. Beun J.J., Paletta F., van Loosdrecht M.C.M., Heijnen J.J. Stoichiometry and kinetics of poly-beta-hydroxybutyrate metabolism in aerobic, slow growing, activated sludge cultures. Biotechnol. Bioeng. 2000, 67(4):379-389.
44. Pala-Ozkok I., Rehman A., Kor-Bicakci G., Ural A., Schilhabel M.B., Ubay-Cokgor E., Jonas D., Orhon D. Effect of sludge age on population dynamics and acetate utilization kinetics under aerobic conditions. Bioresour. Technol. 2013, 143:68-75.
45. Grady C.P.L., Smets B.F., Barbeau D.S. Variability in kinetic parameter estimates: a review of possible causes and a proposed terminology. Water Res. 1996, 30(3):742-748.
46. Karahan O., Olmez-Hanci T., Arslan-Alaton I., Orhon D. Modelling biodegradation of nonylphenol ethoxylate in acclimated and non-acclimated microbial cultures. Bioresour. Technol. 2010, 101:8058-8066.
47. Zhang C., Tezel U., Li K., Liu D., Ren R., Jingxuan Du S.G., Pavlostathis Evaluation and modeling of benzalkonium chloride inhibition and biodegradation in activated sludge. Water Res. 2011, 45:1238-1246.
48. Pala-Ozkok I., Kor-Bicakci G., Ural A., Katipoglu-Yazan T., Yagci N., Ubay-Cokgor E., Orhon D. Acute impact of sulfamethoxazole on the utilization of simple and complex substrates by fast growing microbial culture. J. Chem. Technol. Biotechnol. 2013, 10.1002/jctb.4165.
49. Singh R.K., Kumar S., Kumar A. Biodegradation kinetic studies for the removal of p-cresol from wastewater using Gliomastix indicus MTCC 3869. Biochem. Eng. J. 2008, 40:293-303.
50. Li W.W., Li X.D., Zeng K.M. Aerobic biodegradation kinetics of tannic acid in activated sludge system. Biochem. Eng. J. 2009, 43:142-148.
51. Tännler S., Decasper S., Sauer U. Maintenance metabolism and carbon fluxes in Bacillus species. Microb. Cell Fact. 2008, 7:19.
52. Orhon D., Germirli Babuna F., Karahan O. Industrial Wastewater Treatment by Activated Sludge 2009, IWA Publishing, London.
53. Cetecioglu Z., Ince B., Orhon D., Ince O. Acute inhibitory impact of antimicrobials on acetoclastic methanogenic activity. Bioresour. Technol. 2012, 114:109-116.
54. Pala-Ozkok I. Inhibitory Impact of Selected Antibiotics on Biodegradation Characteristic and Microbial Population Under Aerobic Conditions 2012, Ph.D. Thesis, Istanbul Technical University.