Adverse effects of erythromycin on the structure and chemistry of activated sludge

Environmental Pollution

Volumn 158, Issue 3, 2010, Pages 688-693

  Louvet, J N ^a   Giammarino, C ^a   Potier, O ^a   Pons, M N ^a  

^a UNIVERSITÉ DE LORRAINE   (France)

Author keywords

Antibiotic; Inhibition; Macrolide; Nitrification; Toxicity

Indexed keywords

ACTIVATED SLUDGE; ACTIVATED SLUDGE FLOCS; ADVERSE EFFECT; AUTOMATED IMAGE ANALYSIS; EVOLUTION RATE; INHIBITION; MACROLIDE; MACROLIDES; NITRIFICATION RATES; SPECIFIC NITRIFICATION RATE; STANDARD DEVIATION; SUSPENDED SOLIDS; URBAN WASTEWATER TREATMENT PLANTS;

AMINO ACIDS; ANTIBIOTICS; BIOACTIVITY; DENITRIFICATION; HIGH ENERGY PHYSICS; IMAGE ANALYSIS; NITRIFICATION; OXIDATION; OXYGEN; STATISTICS; TOXICITY; WASTEWATER; WASTEWATER RECLAMATION; WASTEWATER TREATMENT; WATER TREATMENT PLANTS;

CHEMICAL OXYGEN DEMAND;

AMMONIA; AZITHROMYCIN; CIPROFLOXACIN; CLARITHROMYCIN; ENOXACIN; ERYTHROMYCIN; LINCOMYCIN; NITROGEN; NORFLOXACIN; OFLOXACIN; OXYGEN; ROXITHROMYCIN; SULFAMETHOXAZOLE; TRYPTOPHAN;

ACTIVATED SLUDGE; ANTIBIOTICS; CHEMICAL OXYGEN DEMAND; INHIBITION; NITRIFICATION; TOXICITY; WASTEWATER;

ACTIVATED SLUDGE; ARTICLE; CHEMICAL OXYGEN DEMAND; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EFFLUENT; FLUORESCENCE ANALYSIS; FRANCE; IMAGE ANALYSIS; INHIBITION KINETICS; NITRIFICATION; SUSPENDED PARTICULATE MATTER; URBAN AREA; WASTE WATER; WASTE WATER TREATMENT PLANT;

ANTI-BACTERIAL AGENTS; BACTERIA; BIODEGRADATION, ENVIRONMENTAL; BIOREACTORS; CHEMICAL PROCESSES; ENVIRONMENTAL MONITORING; ERYTHROMYCIN; FLOCCULATION; OXYGEN; SEWAGE;

EID: 74149093370     PISSN: 02697491     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.envpol.2009.10.021     Document Type: Article

References (31)

1. Al-Ahmad A., Haiβ A., Unger J., Brunswick-Tietze A., Wiethan J., and Kümmerer K. Effects of a realistic mixture of antibiotics on resistant and nonresistant sewage sludge bacteria in laboratory-scale treatment plants. Archives of Environmental Contamination and Toxicology 57 (2009) 264-273
2. Alighardashi A., Pandolfi D., Potier O., and Pons M.N. Acute sensitivity of activated sludge bacteria to erythromycin. Journal of Hazardous Materials 172 (2009) 685-692
3. Baquero F., Martinez J.L., and Canton R. Antibiotics and antibiotic resistance in water environments. Current Opinion in Biotechnology 19 (2008) 260-265
4. Batt A.L., Bruce I.B., and Aga D.S. Evaluating the vulnerability of surface waters to antibiotic contamination from varying wastewater treatment plant discharges. Environmental Pollution 142 (2006) 295-302
5. Brain R.A., Bestarie K.J., Sanderson H., Hanson M.L., Wilson C.J., Johnson D.J., Sibley P.K., and Solomon K.R. Aquatic microcosm assessment of the effects of tylosin on Lemna gibba and Myriophyllum spicatum. Environmental Pollution 133 (2005) 389-401
6. Brown K.D., Kulis J., Thomson B., Chapman T.H., and Mawhinney D.B. Occurrence of antibiotics in hospital, residential, and dairy effluent, municipal wastewater, and the Rio Grande in New Mexico. Science of the Total Environment 366 (2006) 772-783
7. Campos J.L., Garrido J., Méndez M.R., and Lema J.M. Effect of two broad-spectrum antibiotics on activity and stability of continuous nitrifying system. Applied Biochemistry and Biotechnology 95 (2001) 1-10
8. Da Motta M., Pons M.N., Roche N., and Vivier H. Characterization of activated sludge by automated image analysis. Biochemical Engineering Journal 9 (2001) 165-173
9. Focazio M.J., Kolpin D.W., Barnes K.K., Furlong E.T., Meyer M.T., Zaugg S.D., Barber L.B., and Thurm M. A national reconnaissance for pharmaceuticals and other organic wastewater contaminants in the United States - II) untreated drinking water sources. Science of the Total Environment 402 (2008) 201-216
10. Göbel A., Thomsen A., Mcardell C.S., Joss A., and Giger W. Occurrence and sorption behavior of sulfonamides, macrolides, and trimethoprim in activated sludge treatment. Environmental Science and Technology 39 (2005) 3981-3989
11. Gros M., Petrović M., and Barceló D. Wastewater treatment plants as a pathway for aquatic contamination by pharmaceuticals in the Ebro river basin (Northeast Spain). Environmental Chemistry 26 (2007) 1553-1562
12. Gulkowska A., Leung H.W., So M.K., Taniyasu S., Yamashita N., Yeung L.W.Y., Richardson B.J., Lei A.P., Giesy J.P., and Lam P.K.S. Removal of antibiotics from wastewater by sewage treatment facilities in Hong Kong and Shenzhen, China. Water Research 42 (2008) 395-403
13. Halling-Sørensen B. Inhibition of aerobic growth and nitrification of bacteria in sewage sludge by antibacterial agents. Archives of Environmental Contamination and Toxicology 40. (2001) 451-460
14. Hartmann A., Alder A.C., Koller T., and Widmer R.M. Identification of fluoroquinolone antibiotics as the main source of umuC genotoxicity in native hospital wastewater. Environmental Toxicology and Chemistry 17 (1998) 377-382
15. Isidori M., Lavorgna M., Nardelli A., Pascarella L., and Parrella A. Toxic and genotoxic evaluation of six antibiotics on non-target organisms. Science of the Total Environment 346 (2005) 87-98
16. ISO 9509:2006. Water Quality -Toxicity Test for Assessing Inhibition of Nitrification of Activated Sludge Microorganisms.
17. Karthikeyan K.G., and Meyer M.T. Occurrence of antibiotics in wastewater treatment facilities in Wisconsin, USA. Science of the Total Environment 361 (2006) 196-207
18. Kolpin D.W., Furlong E.T., Meyer M.T., Thurman E.M., Zaugg S.D., Barber L.B., and Buxton H.T. Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999-2000: a national reconnaissance. Environmental Science and Technology 36 (2002) 1202-1211
19. Kümmerer K. Drugs in the environment: emission of drugs, diagnostic aids and disinfectants into wastewater by hospitals in relation to other sources - a review. Chemosphere 45 (2001) 957-969
20. Kümmerer K. Antibiotics in the aquatic environment - a review - part I. Chemosphere 75 (2009) 417-434
21. Kümmerer K. Antibiotics in the aquatic environment - a review - part II. Chemosphere 75 (2009) 435-441
22. Larsson D.G.J., de Pedro C., and Paxeus N. Effluent from drug manufactures contains extremely high levels of pharmaceuticals. Journal of Hazardous Materials 148 (2007) 751-755
23. Lee Y.J., Lee S.E., Lee D.S., and Kim Y.H. Risk assessment of human antibiotics in Korean aquatic environment. Environmental Toxicology and Pharmacology 26 (2008) 216-221
24. Lin A.Y.C., and Tsai Y.T. Occurrence of pharmaceuticals in Taiwan's surface waters: impact of waste streams from hospitals and pharmaceutical production facilities. Science of the Total Environment 407 (2009) 3793-3802
25. Lopez C., Pons M.N., and Morgenroth E. Evaluation of microscopic techniques (epifluorescence microscopy, CLSM, TPE-LSM) as a basis for the quantitative image analysis of activated sludge. Water Research 39 (2005) 456-468
26. McArdell C.S., Molnar E., Suter M.J.F., and Giger W. Occurrence and fate of macrolide antibiotics in wastewater treatment plants and in the GlattValley Watershed, Switzerland. Environmental Science and Technology 24 (2003) 5479-5486
27. Pons M.N., Le Bonté S., and Potier O. Spectral analysis and fingerprinting for biomedia characterization. Journal of Biotechnology 13 (2004) 211-230
28. Schuster A., Hädrich C., and Kümmerer K. Flows of active pharmaceutical ingredients originating from health care practices on a local, regional, and nationwide level in Germany-is hospital effluent treatment an effective approach for risk reduction?. Water, Air, and Soil Pollution 8 (2008) 457-471
29. Spongberg A.L., and Witter J.D. Pharmaceutical compounds in the wastewater process stream in Northwest Ohio. Science of the Total Environment 397 (2008) 148-157
30. Xu W., Zhang G., Li X., Zouc S., Lia P., Hua Z., and Lia J. Occurrence and elimination of antibiotics at four sewage treatment plants in the Pearl River Delta (PRD), South China. Water Research 41 (2007) 4526-4534
31. Xu W.H., Zhang G., Zou S.C., Li X.D., and Liu Y.C. Determination of selected antibiotics in the Victoria Harbour and the Pearl River, South China using high-performance liquid chromatography-electrospray ionization tandem mass spectrometry. Environmental Pollution 145 (2007) 672-679