Nitrotyrosine: Quantitative Analysis, Mapping in Proteins, and Biological Significance

Biomarkers for Antioxidant Defense and Oxidative Damage: Principles and Practical Applications

Volumn , Issue , 2010, Pages 199-218

  Souza, José M ^a   Bartesaghi, Silvina ^b   Peluffo, Gonzalo ^a   Radi, Rafael ^a  

^a UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^b DEPARTAMENTO DE BIOQUÍMICA   (Uruguay)

Author keywords

3 NT formation pathways in cells under biologically relevant conditions; Elucidating pathways and effects of 3 NT formation in pathophysiological conditions; Identifying specific proteins, sites of nitration and biochemical mechanisms linking protein tyrosine nitration to pathogenesis in causative ways; Limits of quantitation and basal plasma levels of protein 3 nitrotyrosine; Mapping 3 nitrotyrosine in proteins; Nitrotyrosine, quantitative analysis, mapping in proteins and biological significance; Protein 3 NT, biomarker of nitroxidative stress in disease processes; Protein 3 NT, good immunogenic antigen generation of polyclonal and monoclonal antibodies; Protein tyrosine nitration increase, associated with pathogenesis in human and animal models of disease; Tyrosine nitration, routes based on free radical pathways

Indexed keywords

EID: 84886511205     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780813814438.ch12     Document Type: Chapter

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