Enzymatic Antioxidant Defenses

Biomarkers for Antioxidant Defense and Oxidative Damage: Principles and Practical Applications

Volumn , Issue , 2010, Pages 21-33

  Miyamoto, Sayuri ^a   Arai, Hirofumi ^b   Terao, Junji ^c  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b KITAMI INSTITUTE OF TECHNOLOGY   (Japan)

^c UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Antioxidative enzymes, role in homeostatic redox state and their deficiency irreversible damage to body tissues; Atherosclerosis, degenerative disease involving formation of fatty streak and fibrosis in artery tissue; Enzymatic antioxidant defenses; Oxidative stress, cardiovascular disease pathogenesis heart attacks, cerebral ischemia and atherosclerosis; Oxidative stress, cellular and extracellular redox state shifting to oxidative side disruption of balance of reactive oxygen species (ROS); Paraoxonase 1 (PON 1), HDL associated enzyme hydrolyzing organophosphates, aromatic carboxylic esters and carbamates; PON activity reduction oxidative stress induced by aging, smoking and obesity; ROS attack on lipids in biomembranes and plasma proteins biomarkers for oxidative stress and antioxidant defense; Superoxide dismutase (SOD) as ROS scavenging system; Understanding physiological function of PON 1 and PAF acetylhydrolase in HDL in LDL oxidation protection

Indexed keywords

EID: 84886505355     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780813814438.ch2     Document Type: Chapter

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