Mass spectrometric investigation of chelerythrine and dihydrochelerythrine biotransformation patterns in human hepatocytes

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 941, Issue , 2013, Pages 17-24

  Vacek, Jan ^a   Papoušková, Barbora ^a   Kosina, Pavel ^a   Galandáková, Adéla ^a   Ulrichová, Jitka ^a  

^a PALACKÝ UNIVERSITY   (Czech Republic)

Author keywords

Benzo c phenanthridines; Chelerythrine; Dihydrochelerythrine; Human hepatocytes; Metabolic transformation

Indexed keywords

BENZO[C]PHENANTHRIDINES; CHELERYTHRINE; DIHYDROCHELERYTHRINE; HUMAN HEPATOCYTES; METABOLIC TRANSFORMATIONS;

BIOCONVERSION; BIOMOLECULES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

METABOLITES;

ALKALOID; CHELERYTHRINE; DIHYDROCHELERYTHRINE; GLUCURONIDE; SANGUINARINE; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG TRANSFORMATION; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LIQUID CHROMATOGRAPHY; LIVER CELL; MALE; MASS SPECTROMETRY; PRIMARY CULTURE; PRIORITY JOURNAL; QUADRUPOLE MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY;

BENZO[C]PHENANTHRIDINES; CHELERYTHRINE; DIHYDROCHELERYTHRINE; HUMAN HEPATOCYTES; METABOLIC TRANSFORMATION;

BENZOPHENANTHRIDINES; BIOTRANSFORMATION; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HEPATOCYTES; HUMANS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84886486526     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2013.09.037     Document Type: Article

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