Scolopendra subspinipes mutilans attenuates neuroinflammation in symptomatic hSOD1G93A mice

Journal of Neuroinflammation

Volumn 10, Issue , 2013, Pages

  Cai, MuDan ^a   Choi, Sun Mi ^a   Song, Bong K ^b   Son, Ilhong ^b   Kim, Sungchul ^b   Yang, Eun J ^a  

^a Korea Institute of Oriental Medicine (KIOM)   (South Korea)

^b Wonkwang University   (South Korea)

Author keywords

Amyotrophic lateral sclerosis; Neuroinflammation; Scolopendra subspinipes mutilans

Indexed keywords

CD14 ANTIGEN; HEME OXYGENASE 1; NATURAL PRODUCT; PROTEIN IBA 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (QUINONE); UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTROCYTE; BRAIN STEM; CELL ACTIVATION; CONTROLLED STUDY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MICROGLIA; MOTONEURON; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; OXIDATIVE STRESS; PROTEIN ANALYSIS; SCOLOPENDRA; SCOLOPENDRA SUBSPINIPES MUTILANS; SPINAL CORD; TRANSGENIC MOUSE; WESTERN BLOTTING;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BLOTTING, WESTERN; BRAIN STEM; DISEASE MODELS, ANIMAL; DRUGS, CHINESE HERBAL; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MICE; MICE, TRANSGENIC; OXIDATIVE STRESS; SPINAL CORD; SUPEROXIDE DISMUTASE;

EID: 84886441872     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-10-131     Document Type: Article

References (42)

1. Swarup V, Julien JP. ALS pathogenesis: recent insights from genetics and mouse models. Prog Neuropsychopharmacol Biol Psychiatry 2011, 35:363-369. 10.1016/j.pnpbp.2010.08.006, 20728492.
2. Gurney ME, Pu H, Chiu AY, Dal Canto MC, Polchow CY, Alexander DD, Caliendo J, Hentati A, Kwon YW, Deng HX, et al. Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation. Science 1994, 264:1772-1775. 10.1126/science.8209258, 8209258.
3. Barber SC, Shaw PJ. Oxidative stress in ALS: key role in motor neuron injury and therapeutic target. Free Radic Biol Med 2010, 48:629-641. 10.1016/j.freeradbiomed.2009.11.018, 19969067.
4. Akiyama H, Barger S, Barnum S, Bradt B, Bauer J, Cole GM, Cooper NR, Eikelenboom P, Emmerling M, Fiebich BL, et al. Inflammation and Alzheimer's disease. Neurobiol Aging 2000, 21:383-421. 10.1016/S0197-4580(00)00124-X, 10858586.
5. Liao B, Zhao W, Beers DR, Henkel JS, Appel SH. Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS. Exp Neurol 2012, 237:147-152. 10.1016/j.expneurol.2012.06.011, 22735487.
6. Phani S, Re DB, Przedborski S. The role of the innate immune system in ALS. Front Pharmacol 2012, 3:150. 3418523, 22912616.
7. Philips T, Robberecht W. Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease. Lancet Neurol 2011, 10:253-263. 10.1016/S1474-4422(11)70015-1, 21349440.
8. Pemberton RW. Insects and other arthropods used as drugs in Korean traditional medicine. J Ethnopharmacol 1999, 65:207-216. 10.1016/S0378-8741(98)00209-8, 10404418.
9. Jiang Su New Medical College Zhong-yao-da-ci-dian (Dictionary of Chinese Crude Drugs) 1977, Shanghai, China: Shanghai Scientific Technologic Publishers, Jiang Su New Medical College.
10. Zhou YQ, Han L, Liu ZQ, Du KC, Li KY. Effect of centipede extract on cervical tumor of mice and its mechanism. Zhong Yao Cai 2011, 34:859-864.
11. Xu XL, Wang CM, Geng D, Zhang L, Hu B. Effects of centipede extracts on normal mouse and S180, H22 bearing mouse. Zhong Yao Cai 2010, 33:499-503.
12. Zhao H, Li Y, Wang Y, Zhang J, Ouyang X, Peng R, Yang J. Antitumor and immunostimulatory activity of a polysaccharide-protein complex from Scolopendra subspinipes mutilans L. Koch in tumor-bearing mice. Food Chem Toxicol 2012, 50:2648-2655. 10.1016/j.fct.2012.05.018, 22613217.
13. Kim K, Kim H, Park K, Cho K. Structural characterization of a new antibiotic substance purified from Scolopendra Subspinipes Multilans L Koch. J Korean Chem Soc 1998, 42:236-239.
14. Yang EJ, Jiang JH, Lee SM, Yang SC, Hwang HS, Lee MS, Choi SM. Bee venom attenuates neuroinflammatory events and extends survival in amyotrophic lateral sclerosis models. J Neuroinflammation 2010, 7:69. 10.1186/1742-2094-7-69, 2974667, 20950451.
15. Yin CS, Jeong HS, Park HJ, Baik Y, Yoon MH, Choi CB, Koh HG. A proposed transpositional acupoint system in a mouse and rat model. Res Vet Sci 2008, 84:159-165. 10.1016/j.rvsc.2007.04.004, 17559895.
16. Yang EJ, Jiang JH, Lee SM, Hwang HS, Lee MS, Choi SM. Electroacupuncture reduces neuroinflammatory responses in symptomatic amyotrophic lateral sclerosis model. J Neuroimmunol 2010, 223:84-91. 10.1016/j.jneuroim.2010.04.005, 20460191.
17. Irugalbandara ZE. Simplified differentiation of Nissl granules stained by toluidine blue in paraffin sections. Stain Technol 1960, 35:47-48.
18. Zhang X, Chen S, Li L, Wang Q, Le W. Decreased level of 5-methyltetrahydrofolate: a potential biomarker for pre-symptomatic amyotrophic lateral sclerosis. J Neurol Sci 2010, 293:102-105. 10.1016/j.jns.2010.02.024, 20334883.
19. Kim H, Kim HY, Choi MR, Hwang S, Nam KH, Kim HC, Han JS, Kim KS, Yoon HS, Kim SH. Dose-dependent efficacy of ALS-human mesenchymal stem cells transplantation into cisterna magna in SOD1-G93A ALS mice. Neurosci Lett 2010, 468:190-194. 10.1016/j.neulet.2009.10.074, 19879334.
20. Cai M, Shin BY, Kim DH, Kim JM, Park SJ, Park CS, Won Do H, Hong ND, Kang DH, Yutaka Y, Ryu JH. Neuroprotective effects of a traditional herbal prescription on transient cerebral global ischemia in gerbils. J Ethnopharmacol 2011, 138:723-730. 10.1016/j.jep.2011.10.016, 22020275.
21. Schmued LC, Albertson C, Slikker W. Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration. Brain Res 1997, 751:37-46. 10.1016/S0006-8993(96)01387-X, 9098566.
22. Hopkins KJ, Wang G, Schmued LC. Temporal progression of kainic acid induced neuronal and myelin degeneration in the rat forebrain. Brain Res 2000, 864:69-80. 10.1016/S0006-8993(00)02137-5, 10793188.
23. Cai M, Phan PT, Hong JG, Kim DH, Kim JM, Park SJ, Liu X, Han JE, Park H, Choi JW, Ryu JH. The neuroprotective effect of eupatilin against ischemia/reperfusion-induced delayed neuronal damage in mice. Eur J Pharmacol 2012, 689:104-110. 10.1016/j.ejphar.2012.05.042, 22683875.
24. Manabe Y, Nagano I, Gazi MS, Murakami T, Shiote M, Shoji M, Kitagawa H, Abe K. Glial cell line-derived neurotrophic factor protein prevents motor neuron loss of transgenic model mice for amyotrophic lateral sclerosis. Neurol Res 2003, 25:195-200. 10.1179/016164103101201193, 12635522.
25. Kieran D, Kalmar B, Dick JR, Riddoch-Contreras J, Burnstock G, Greensmith L. Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice. Nat Med 2004, 10:402-405. 10.1038/nm1021, 15034571.
26. Yang EJ, Kim SH, Yang SC, Lee SM, Choi SM. Melittin restores proteasome function in an animal model of ALS. J Neuroinflammation 2011, 8:69. 10.1186/1742-2094-8-69, 3142224, 21682930.
27. Sugiyama M, Takao M, Hatsuta H, Funabe S, Ito S, Obi T, Tanaka F, Kuroiwa Y, Murayama S. Increased number of astrocytes and macrophages/microglial cells in the corpus callosum in amyotrophic lateral sclerosis. Neuropathology 2013, [Epub ahead of print].
28. Evans MC, Couch Y, Sibson N, Turner MR. Inflammation and neurovascular changes in amyotrophic lateral sclerosis. Mol Cell Neurosci 2013, 53:34-41.
29. Knysak I, Martins R, Bertim CR. Epidemiological aspects of centipede (Scolopendromorphae: Chilopoda) bites registered in greater S. Paulo, SP, Brazil. Rev Saude Publica 1998, 32:514-518. 10.1590/S0034-89101998000600003, 10349142.
30. Gomes A, Datta A, Sarangi B, Kar PK, Lahiri SC. Isolation, purification & pharmacodynamics of a toxin from the venom of the centipede Scolopendra subspinipes dehaani Brandt. Indian J Exp Biol 1983, 21:203-207.
31. You WK, Sohn YD, Kim KY, Park DH, Jang Y, Chung KH. Purification and molecular cloning of a novel serine protease from the centipede, Scolopendra subspinipes mutilans. Insect Biochem Mol Biol 2004, 34:239-250. 10.1016/j.ibmb.2003.10.003, 14871620.
32. Ren Y, Houghton P, Hider RC. Relevant activities of extracts and constituents of animals used in traditional Chinese medicine for central nervous system effects associated with Alzheimer's disease. J Pharm Pharmacol 2006, 58:989-996. 10.1211/jpp.58.7.0015, 16805960.
33. Nagai M, Re DB, Nagata T, Chalazonitis A, Jessell TM, Wichterle H, Przedborski S. Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons. Nat Neurosci 2007, 10:615-622. 10.1038/nn1876, 3799799, 17435755.
34. Van Damme P, Bogaert E, Dewil M, Hersmus N, Kiraly D, Scheveneels W, Bockx I, Braeken D, Verpoorten N, Verhoeven K, et al. Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity. Proc Natl Acad Sci USA 2007, 104:14825-14830. 10.1073/pnas.0705046104, 1976195, 17804792.
35. Boillee S, Yamanaka K, Lobsiger CS, Copeland NG, Jenkins NA, Kassiotis G, Kollias G, Cleveland DW. Onset and progression in inherited ALS determined by motor neurons and microglia. Science 2006, 312:1389-1392. 10.1126/science.1123511, 16741123.
36. Yamanaka K, Chun SJ, Boillee S, Fujimori-Tonou N, Yamashita H, Gutmann DH, Takahashi R, Misawa H, Cleveland DW. Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis. Nat Neurosci 2008, 11:251-253. 10.1038/nn2047, 3137510, 18246065.
37. Shaw PJ, Ince PG, Falkous G, Mantle D. Oxidative damage to protein in sporadic motor neuron disease spinal cord. Ann Neurol 1995, 38:691-695. 10.1002/ana.410380424, 7574472.
38. Beal MF, Ferrante RJ, Browne SE, Matthews RT, Kowall NW, Brown RH. Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis. Ann Neurol 1997, 42:644-654. 10.1002/ana.410420416, 9382477.
39. Shibata N, Nagai R, Uchida K, Horiuchi S, Yamada S, Hirano A, Kawaguchi M, Yamamoto T, Sasaki S, Kobayashi M. Morphological evidence for lipid peroxidation and protein glycoxidation in spinal cords from sporadic amyotrophic lateral sclerosis patients. Brain Res 2001, 917:97-104. 10.1016/S0006-8993(01)02926-2, 11602233.
40. Dwyer BE, Lu SY, Nishimura RN. Heme oxygenase in the experimental ALS mouse. Exp Neurol 1998, 150:206-212. 10.1006/exnr.1997.6763, 9527889.
41. Orozco-Ibarra M, Chirino YI, Pedraza-Chaverri J. Role of hemeoxygenase-1 in the neurodegenerative disorders. Rev Neurol 2006, 43:556-562.
42. Tsvetkov P, Reuven N, Shaul Y. Ubiquitin-independent p53 proteasomal degradation. Cell Death Differ 2010, 17:103-108. 10.1038/cdd.2009.67, 19557012.