Enhanced liver autophagic activity improves survival of septic mice lacking surfactant proteins A and D

Tohoku Journal of Experimental Medicine

Volumn 231, Issue 2, 2013, Pages 127-138

  Tang, Zhe ^a,b   Ni, Lan ^a,c   Javidiparsijani, Sara ^a   Hu, Fengqi ^a   Gatto, Louis A ^a,d   Cooney, Robert ^a   Wang, Guirong ^a  

^a State University of New York Upstate Medical University: College of Medicine   (United States)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c WUHAN UNIVERSITY   (China)

^d STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

Autophagy; Innate immunity; Sepsis; Signaling pathway; Surfactant protein

Indexed keywords

SURFACTANT PROTEIN A; SURFACTANT PROTEIN D;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HISTOPATHOLOGY; LIVER FUNCTION; MALE; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; SEPSIS; SIGNAL TRANSDUCTION; SURVIVAL RATE; WILD TYPE;

ANALYSIS OF VARIANCE; ANIMALS; AUTOPHAGY; BLOTTING, WESTERN; HEPATOCYTES; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, ELECTRON; PULMONARY SURFACTANT-ASSOCIATED PROTEIN A; PULMONARY SURFACTANT-ASSOCIATED PROTEIN D; REAL-TIME POLYMERASE CHAIN REACTION; SEPSIS; SIGNAL TRANSDUCTION;

EID: 84886432225     PISSN: 00408727     EISSN: 13493329     Source Type: Journal    
DOI: 10.1620/tjem.231.127     Document Type: Article

References (43)

1. Abraham, E. & Singer, M. (2007) Mechanisms of sepsis-induced organ dysfunction. Crit. Care Med., 35, 2408-2416.
2. Angus, D.C., Linde-Zwirble, W.T., Lidicker, J., Clermont, G., Carcillo, J. & Pinsky, M.R. (2001) Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit. Care Med., 29, 1303-1310.
3. Anthony Fauci, D.L. (2011) Harrison's Principles of Internal Medicine. In Harrison's Principles of Internal Medicine (McGraw-Hill Professional), p. 2223.
4. Ayala, A., Perl, M., Venet, F., Lomas-Neira, J., Swan, R. & Chung, C.S. (2008) Apoptosis in sepsis: mechanisms, clinical impact and potential therapeutic targets. Curr. Pharm. Des., 14, 1853-1859.
5. Borner, C. (2003) The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions. Mol. Immunol., 39, 615-647.
6. Carchman, E.H., Rao, J., Loughran, P.A., Rosengart, M.R. & Zuckerbraun, B.S. (2011) Heme oxygenase-1-mediated autophagy protects against hepatocyte cell death and hepatic injury from infection/sepsis in mice. Hepatology, 53, 2053-2062.
7. Carrico, C.J., Meakins, J.L., Marshall, J.C., Fry, D. & Maier, R.V. (1986) Multiple-organ-failure syndrome. Arch. Surg., 121, 196-208.
8. Cerra, F.B., Siegel, J.H., Border, J.R., Wiles, J. & McMenamy, R.R. (1979) The hepatic failure of sepsis: cellular versus substrate. Surgery, 86, 409-422.
9. Chien, W.S., Chen, Y.H., Chiang, P.C., Hsiao, H.W., Chuang, S.M., Lue, S.I. & Hsu, C. (2011) Suppression of autophagy in rat liver at late stage of polymicrobial sepsis. Shock, 35, 506-511.
10. Choi, A.J. & Ryter, S.W. (2011) Autophagy in inflammatory diseases. Int. J. Cell Biol., 2011, 732798 [Epub ahead of print].
11. Dhainaut, J.F., Marin, N., Mignon, A. & Vinsonneau, C. (2001) Hepatic response to sepsis: interaction between coagulation and inflammatory processes. Crit. Care Med., 29, S42-47.
12. Djavaheri-Mergny, M., Amelotti, M., Mathieu, J., Besancon, F., Bauvy, C., Souquere, S., Pierron, G. & Codogno, P. (2006) NF-kappaB activation represses tumor necrosis factor-alpha-induced autophagy. J. Biol. Chem., 281, 30373-30382.
13. Eisenberg-Lerner, A., Bialik, S., Simon, H.U. & Kimchi, A. (2009) Life and death partners: apoptosis, autophagy and the crosstalk between them. Cell Death Differ., 16, 966-975.
14. Eskelinen, E.L. & Saftig, P. (2009) Autophagy: a lysosomal degradation pathway with a central role in health and disease. Biochim. Biophys. Acta, 1793, 664-673.
15. Gardai, S.J., Xiao, Y.Q., Dickinson, M., Nick, J.A., Voelker, D.R., Greene, K.E. & Henson, P.M. (2003) By binding SIRPalpha or calreticulin/CD91, lung collectins act as dual function surveillance molecules to suppress or enhance inflammation. Cell, 115, 13-23.
16. Haagsman, H.P., Hogenkamp, A., van Eijk, M. & Veldhuizen, E.J. (2008) Surfactant collectins and innate immunity. Neona-tology, 93, 288-294.
17. Hawgood, S., Ochs, M., Jung, A., Akiyama, J., Allen, L., Brown, C., Edmondson, J., Levitt, S., Carlson, E., Gillespie, A.M., Villar, A., Epstein, C.J. & Poulain, F.R. (2002) Sequential targeted defciency of SP-A and -D leads to progressive alveolar lipoproteinosis and emphysema. Am. J. Physiol. Lung Cell Mol. Physiol., 283, L1002-1010.
18. Hotchkiss, R.S., Coopersmith, C.M., McDunn, J.E. & Ferguson, T.A. (2009) The sepsis seesaw: tilting toward immunosuppression. Nat. Med., 15, 496-497.
19. Hotchkiss, R.S., Strasser, A., McDunn, J.E. & Swanson, P.E. (2009) Cell death. N. Engl. J. Med., 361, 1570-1583.
20. Knaus, W.A., Draper, E.A., Wagner, D.P. & Zimmerman, J.E. (1985) Prognosis in acute organ-system failure. Ann. Surg., 202, 685-693.
21. Levine, B. & Kroemer, G. (2008) Autophagy in the pathogenesis of disease. Cell, 132, 27-42.
22. Levine, B. & Yuan, J. (2005) Autophagy in cell death: an innocent convict? J. Clin. Invest., 115, 2679-2688.
23. Li, H., Zhu, H., Xu, C.J. & Yuan, J. (1998) Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell, 94, 491-501.
24. Madsen, J., Kliem, A., Tornoe, I., Skjodt, K., Koch, C. & Holmskov, U. (2000) Localization of lung surfactant protein D on mucosal surfaces in human tissues. J. Immunol., 164, 5866-5870.
25. Manukyan, M.C., Weil, B.R., Wang, Y., Abarbanell, A.M., Herrmann, J.L., Poynter, J.A. & Meldrum, D.R. (2010) The phosphoinositide-3 kinase survival signaling mechanism in sepsis. Shock, 34, 442-449.
26. Martin, G.S., Mannino, D.M., Eaton, S. & Moss, M. (2003) The epidemiology of sepsis in the United States from 1979 through 2000. N. Engl. J. Med., 348, 1546-1554.
27. Mizushima, N. (2009) Physiological functions of autophagy. Curr. Top. Microbiol. Immunol., 335, 71-84.
28. Mizushima, N. & Komatsu, M. (2011) Autophagy: renovation of cells and tissues. Cell, 147, 728-741.
29. Mizushima, N., Levine, B., Cuervo, A.M. & Klionsky, D.J. (2008) Autophagy fights disease through cellular self-digestion. Nature, 451, 1069-1075.
30. Munz, C. (2009) Enhancing immunity through autophagy. Annu. Rev. Immunol., 27, 423-449.
31. Nakahira, K., Haspel, J.A., Rathinam, V.A., Lee, S.J., Dolinay, T., Lam, H.C., Englert, J.A., Rabinovitch, M., Cernadas, M., Kim, H.P., Fitzgerald, K.A., Ryter, S.W. & Choi, A.M. (2011) Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat. Immunol., 12, 222-230.
32. Puissant, A., Fenouille, N. & Auberger, P. (2012) When autophagy meets cancer through p62/SQSTM1. Am. J. Cancer Res., 2, 397-413.
33. Rittirsch, D., Huber-Lang, M.S., Flierl, M.A. & Ward, P.A. (2009) Immunodesign of experimental sepsis by cecal ligation and puncture. Nat. Protoc., 4, 31-36.
34. Seaton, B.A., Crouch, E.C., McCormack, F.X., Head, J.F., Hartshorn, K.L. & Mendelsohn, R. (2010) Review: Structural determinants of pattern recognition by lung collectins. Innate. Immun., 16, 143-150.
35. Tanida, I. (2011) Autophagosome formation and molecular mechanism of autophagy. Antioxid. Redox Signal., 14, 2201-2214.
36. Wang, G., Christensen, N.D., Wigdahl, B., Guttentag, S.H. & Floros, J. (2003) Differences in N-linked glycosylation between human surfactant protein-B variants of the C or T allele at the single-nucleotide polymorphism at position 1580: implications for disease. Biochem. J., 369, 179-184.
37. Wang, G., Guo, X., Diangelo, S., Thomas, N.J. & Floros, J. (2010) Humanized SFTPA1 and SFTPA2 transgenic mice reveal functional divergence of SP-A1 and SP-A2: formation of tubular myelin in vivo requires both gene products. J. Biol. Chem., 285, 11998-12010.
38. Watanabe, E., Muenzer, J.T., Hawkins, W.G., Davis, C.G., Dixon, D.J., McDunn, J.E., Brackett, D.J., Lerner, M.R., Swanson, P.E. & Hotchkiss, R.S. (2009) Sepsis induces extensive autophagic vacuolization in hepatocytes: a clinical and laboratory-based study. Lab. Invest., 89, 549-561.
39. White, L.E., Cui, Y., Shelak, C.M., Lie, M.L. & Hassoun, H.T. (2012) Lung endothelial cell apoptosis during ischemic acute kidney injury. Shock, 38, 320-327.
40. Wright, J.R. (2005) Immunoregulatory functions of surfactant proteins. Nat. Rev. Immunol., 5, 58-68.
41. Wu, Y.Z., Medjane, S., Chabot, S., Kubrusly, F.S., Raw, I., Chignard, M. & Touqui, L. (2003) Surfactant protein-A and phosphatidylglycerol suppress type IIA phospholipase A2 synthesis via nuclear factor-kappaB. Am. J. Respir. Crit. Care Med., 168, 692-699.
42. Yeh, W.C., de la Pompa, J.L., McCurrach, M.E., Shu, H.B., Elia, A.J., Shahinian, A., Ng, M., Wakeham, A., Khoo, W., Mitchell, K., El-Deiry, W.S., Lowe, S.W., Goeddel, D.V. & Mak, T.W. (1998) FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science, 279, 1954-1958.
43. Yeretssian, G., Correa, R.G., Doiron, K., Fitzgerald, P., Dillon, C.P., Green, D.R., Reed, J.C. & Saleh, M. (2011) Non-apop-totic role of BID in inflammation and innate immunity. Nature, 474, 96-99.