The role of serum cholinesterase activity and S100B protein in the evaluation of organophosphate poisoning

Human and Experimental Toxicology

Volumn 32, Issue 10, 2013, Pages 1081-1088

  Yardan, T ^a   Baydin, A ^a   Acar, E ^b   Ulger, F ^a   Aygun, D ^a   Duzgun, A ^a   Nar, R ^a  

^a ONDOKUZ MAYIS UNIVERSITY   (Turkey)

^b Erzurum Region Education and Research Hospital   (Turkey)

Author keywords

Organophosphate poisoning; S100B protein; serum cholinesterase

Indexed keywords

ATROPINE; CHOLINESTERASE; ORGANOPHOSPHATE; PRALIDOXIME; PROTEIN S100B;

ACUTE DISEASE; ADULT; AGED; ARTICLE; BLOOD SAMPLING; CHOLINESTERASE BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; EMERGENCY CARE; ENZYME ACTIVITY; FEMALE; HOSPITAL ADMISSION; HUMAN; MALE; MORTALITY; ORGANOPHOSPHATE POISONING; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; SURVIVAL RATE;

ORGANOPHOSPHATE POISONING; S100B PROTEIN; SERUM CHOLINESTERASE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHOLINESTERASES; FEMALE; HUMANS; MALE; MIDDLE AGED; ORGANOPHOSPHATE POISONING; S100 CALCIUM BINDING PROTEIN BETA SUBUNIT; SEVERITY OF ILLNESS INDEX; YOUNG ADULT;

EID: 84886425005     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327112474850     Document Type: Article

References (34)

1. Eddleston M, Buckley NA, Eyer P, Dawson AH. Management of acute organophosphorus pesticide poisoning. Lancet. 2008 ; 371: 597-607
2. Sungur M, Güven M. Intensive care management of organophosphate insecticide poisoning. Crit Care. 2001 ; 5: 211-215
3. Akdur O, Durukan P, Ozkan S, Avsarogullari L, Vardar A, Kavalci C, et al. Poisoning severity score, glasgow coma scale, corrected QT interval in acute organophosphate poisoning. Hum Exp Toxicol. 2010 ; 29: 419-425
4. Jokanović M. Medical treatment of acute poisoning with organophosphorus and carbamate pesticides. Toxicol Lett. 2009 ; 190: 107-115
5. Costa LG. Current issues in organophosphate toxicology. Clin Chim Acta. 2006 ; 366: 1-13
6. Chen HY, Wang WW, Chaou CH, Lin CC. Prognostic value of serial serum cholinesterase activities in organophosphate poisoned patients. Am J Emerg Med. 2009 ; 27: 1034-1039
7. Nouira S, Abroug F, Elatrous S, Boujdaria R, Bouchoucha S. Prognostic value of serum cholinesterase in organophosphate poisoning. Chest. 1994 ; 106: 1811-1814
8. Aygun D, Doganay Z, Altintop L, Guven H, Onar M, Deniz T, et al. Serum acetylcholinesterase and prognosis of acute organophosphate poisoning. J Toxicol Clin Toxicol. 2002 ; 40: 903-910
9. Bozkurt A, Yardan T, Ciftcioglu E, Baydin A, Hakligor A, Bitigic M, et al. Time course of serum S100B protein and neuron-specific enolase levels of a single dose of chlorpyrifos in rats. Basic Clin Pharmacol Toxicol. 2010 ; 107: 893-898
10. Guizzetti M, Pathak S, Giordano G, Costa LG. Effect of organophosphorus insecticides and their metabolites on astroglial cell proliferation. Toxicology. 2005 ; 215: 182-190
11. Qiao D, Seidler FJ, Slotkin TA. Developmental neurotoxicity of chlorpyrifos modeled in vitro: comparative effects of metabolites and other cholinesterase inhibitors on DNA synthesis in PC12 and C6 cells. Environ Health Perspect. 2001 ; 109: 909-913
12. Caughlan A, Newhouse K, Namgung U, Xia Z. Chlorpyrifos induces apoptosis in rat cortical neurons that is regulated by a balance between p38 and ERK/JNK MAP kinases. Toxicol Sci. 2004 ; 78: 125-134
13. Yardan T, Cevik Y, Donderici O, Kavalci C, Yilmaz FM, Yilmaz G, et al. Elevated serum S100B protein and neuron-specific enolase levels in carbon monoxide poisoning. Am J Emerg Med. 2009 ; 27: 838-842
14. Rothermundt M, Peters M, Prehn JH, Arolt V. S100B in brain damage and neurodegeneration. Microsc Res Technol. 2003 ; 60: 614-632
15. Cakir Z, Aslan S, Umudum Z, Acemoglu H, Akoz A, Turkyilmaz S, et al. S-100beta and neuron-specific enolase levels in carbon monoxide-related brain injury. Am J Emerg Med. 2010 ; 28: 61-67
16. Ambrozic J, Bunc M, Osredkar J, Brvar M. S100B protein in benzodiazepine overdose. Emerg Med J. 2008 ; 25: 90-92
17. Bardin PG, Van Eeden SF. Organophosphate poisoning: grading the severity and comparing treatment between atropine and glycopyrrolate. Crit Care Med. 1990 ; 18: 956-960
18. Bardin PG, Van Eeden SF, Moolman JA, Foden AP, Joubert JR. Organophosphate and carbamate poisoning. Arch Intern Med. 1994 ; 154: 1433-1441
19. Amanvermez R, Baydin A, Yardan T, Basol N, Gunay M. Emergency laboratory abnormalities in suicidal patients with acute organophosphate poisoning. Turk J Biochem. 2010 ; 35: 29-34
20. Brahmi N, Mokline A, Kouraichi N, Ghorbel H, Blel Y, Thabet H, et al. Prognostic value of human erythrocyte acetyl cholinesterase in acute organophosphate poisoning. Am J Emerg Med. 2006 ; 24: 822-827
21. Sungurtekin H, Gürses E, Balci C. Evaluation of several clinical scoring tools in organophosphate poisoned patients. Clin Toxicol (Phila). 2006 ; 44: 121-126
22. Eddleston M, Clark RF Goldfrank's toxicologic emergencies. 9 th ed. New York, NY: McGraw-Hill, 2011, pp. 1450-1466. Nelson LS Lewin NA Howland MA, ed. New York, NY: McGraw-Hill ; 2011: 1450-1466.
23. Oliveira-Silva JJ, Alves SR, Inacio AF, Meyer A, Sarcinelli PN, Mattos RC, et al. Cholinesterase activities determination in frozen blood samples: an improvement to the occupational monitoring in developing countries. Hum Exp Toxicol. 2000 ; 19: 173-177
24. Sam KG, Kondabolu K, Pati D, Kamath A, Pradeep Kumar G, Rao PG. Poisoning severity score, APACHE II and GCS: effective clinical indices for estimating severity and predicting outcome of acute organophosphorus and carbamate poisoning. J Forensic Leg Med. 2009 ; 16: 239-247
25. Grmec S, Mally S, Klemen P. Glasgow Coma Scale score and QTc interval in the prognosis of organophosphate poisoning. Acad Emerg Med. 2004 ; 11: 925-930
26. Abdalla MS, El-Sebaey AS, Badawy SM.. Clinical findings and cholinesterase levels in children of organophosphates and carbamates poisoning. Eur J Pediatr. 2009 ; 168: 951-956
27. Rehiman S, Lohani SP, Bhattarai MC. Correlation of serum cholinesterase level, clinical score at presentation and severity of organophosphorous poisoning. JNMA J Nepal Med Assoc. 2008 ; 47: 47-52
28. Yun HW, Lee DH, Lee JH, Cheon YJ, Choi YH. Serial serum cholinesterase activities as a prognostic factor in organophosphate poisoned patients. Hong Kong J Emerg Med. 2012 ; 19: 92-97
29. Garcia SJ, Seidler FJ, Crumpton TL, Slotkin TA. Does the developmental neurotoxicity of chlorpyrifos involve glial targets? Macromolecule synthesis, adenylyl cyclase signaling, nuclear transcription factors, and formation of reactive oxygen in C6 glioma cells. Brain Res. 2001 ; 891: 54-68
30. Zurich MG, Honegger P, Schilter B, Costa LG, Monnet-Tschudi F. Involvement of glial cells in the neurotoxicity of parathion and chlorpyrifos. Toxicol Appl Pharmacol. 2004 ; 201: 97-104
31. Nedzvetsky VS, Tuzcu M, Yasar A, Tikhomirov AA, Baydas G. Effects of vitamin E against aluminum neurotoxicity in rats. Biochemistry (Mosc). 2006 ; 71: 239-244
32. Foerch C, Singer OC, Neumann-Haefelin T, Du Mesnil de Rochemont R, Steinmetz H, Sitzer M. Evaluation of serum S100B as a surrogate marker for long-term outcome and infarct volume in acute middle cerebral artery infarction. Arch Neurol. 2005 ; 62: 1130-1134
33. Hu YY, Dong XQ, Yu WH, Zhang ZY. Change in plasma S100B level after acute spontaneous basal ganglia hemorrhage. Shock. 2010 ; 33: 134-140
34. Hayakata T, Shiozaki T, Tasaki O, Ikegawa H, Inoue Y, Toshiyuki F, et al. Changes in CSF S100B and cytokine concentrations in early-phase severe traumatic brain injury. Shock. 2004 ; 22: 102-107