Correlation of serum cholinesferase level, clinical score of presentation and severity of Organophosphorous Poisoning

Journal of the Nepal Medical Association

Volumn 47, Issue 170, 2008, Pages 47-52

  Rehiman, S ^a   Lohani, S P ^b   Bhattarai, M D ^c  

^a Medical Trust Hospital   (India)

^b Nepal Poison Center   (Nepal)

^c BIR HOSPITAL   (Nepal)

Author keywords

Organophosphorous poisoning; Peradeniya organophosphorous poisoning scale; Serum cholinesterase

Indexed keywords

ATROPINE; CHOLINESTERASE; ORGANOPHOSPHORUS COMPOUND; PRALIDOXIME; MUSCARINIC RECEPTOR BLOCKING AGENT; ORGANOPHOSPHATE;

ADOLESCENT; ADULT; AGED; ARTICLE; CHI SQUARE TEST; CHOLINESTERASE BLOOD LEVEL; COMORBIDITY; CORRELATION COEFFICIENT; DISEASE SEVERITY; DRUG INFUSION; FEMALE; FISHER EXACT TEST; HOSPITALIZATION; HUMAN; INTOXICATION; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MORBIDITY; ORGANOPHOSPHORUS POISONING SCALE; PATIENT MONITORING; RATING SCALE; STATISTICAL SIGNIFICANCE; BLOOD; MIDDLE AGED; MORTALITY; PREDICTION AND FORECASTING; PROGNOSIS; PROSPECTIVE STUDY;

ADOLESCENT; ADULT; AGED; ATROPINE; CHOLINESTERASES; FEMALE; HUMANS; MALE; MIDDLE AGED; MUSCARINIC ANTAGONISTS; PHOSPHORIC ACID ESTERS; POISONING; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; YOUNG ADULT;

EID: 48649090133     PISSN: 00282715     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Pokhrel N, Gurung CK. A study of poison cases recorded in Bir Hospital over four years. J Inst Med 1987;9:29-34.
2. Suvedi BK. A retrospective study of poisoning cases at Bir Hospital, Nepal. J Inst Med 1990;12:296-302.
3. Kafle KK, Gyawali KK. Organophosphorus - Commonest poisoning agent. J Inst Med 1992;14:228-33.
4. Prasad PN, Karki P. Poisoning cases at TUTH emergency; a one-year review. J Inst Med 1997;19:18-24.
5. Rauniyar GP, Das BP, Naga Rani MA, Gupta MP, Karki BMS. Retrospective analysis of profile of acute poisoning cases in a tertiary care hospital in eastern Nepal: A four-year database from 1994 to 1997. J Nep Med Assoc 1999;38:23-8.
6. Bharati U, Shrestha JB, Sharma M. Study of acute poisoning in Nepal Medical College Teaching Hospital. Nep Med Col J 2000;2:83-5.
7. Pathak UN, Chhetri PK, Dhungel S, Chokhani R, Devkota KC, Shrestha BO, et al. Retrospective study of poisoning cases admitted in Nepal Medical College Teaching Hospital. Nep Med Col J 2001;3:101-5.
8. Ghimire RH, Sharma SP, Pandey KR. A retrospective study of the changing trends of poisoning cases at Tribhuvan University Teaching Hospital, Nepal between 1990-1992 and 2000-2002. J Nep Health Res Council 2003:6-16.
9. Karki P, Ansari JA, Bhandary S, Koirala S. Cardiac and electrocardiographical manifestations of acute organophosphate poisoning. Singapore Med J 2004;45:385-9.
10. Khadka SB, Ale SB. A study of poisoning cases in emergency Kathmandu Medical College Teaching Hospital. Kathmandu Univ Med J 2005;3:388-91.
11. Paudyal BP. Poisoning: Pattern and profile of admitted cases in a hospital in central Nepal. J Nep Med Assoc 2005;44:92-6.
12. Karki P, Hansdak SG, Bhundari S, Shukla A, Koirala S. A clinico-epidemiological study of organophosphorous poisoning at a rural based teaching hospital of eastern Nepal. Trop Doct 2001;31:32-4.
13. Paudyal Kshatri LB. insecticide poisoning [master's theses].[Kathmandu]: Institute of Medicine, TUTH;1998.
14. Senanayake N, de Silva HJ, Karalliedde L. A scale to assess severity in organophosphorus intoxication: POP scale. Hum Exp Toxicol 1993;12:297-9.
15. Batra AK, Keoliy AN, Jadhav GU. Poisoning : an unnatural cause of morbidity and mortality in rural India. J Assoc Phy Ind 2003;51:955-9.
16. Indian Council of Medical Research. Pesticide Pollution: Trends and Perspective. Ind Council Med Res Bull 2001;31:367-71.
17. Bhattarai MD, Singh DL, Chalise BS, Koirala P. A case report and overview of organophosphate (OP) poisoning. Kathmandu Univ Med J 2006;4,100-4.
18. Eddleston M, Karalliedde L, Senanayake N, Sheriff R, Singh S. Pesticide poisoning in the developing world a minimum pesticides list. Lancet 2002;360:1163-7.
19. Gupta SK, Joshi MP. Pesticide poisoning cases attending five major hospitals of Nepal. J Nep Med Assoc 2002;41:447-56.
20. Senanayake N, Karalliedde L. Neurotoxic effects of organophosphorus insecticides: An intermediate syndrome. N Engl J Med 1987;316:761-3.
21. Wadia RS. Organophosphate poisoning. In: Shah SN, Anand MP, Acharya VN, Karnad DR, Bichile SK, Kamath SA, et al, eds. API Text Book of Medicine 7th ed. Mumbai: The Association of Physicians of India 2003:1271-2.
22. Jha S, Chandra M, Sondhi D. OP poisoning and interpretation of its clinical study and management. Ind Med Gazette 1989;123:108-10.
23. Goel A, Joseph S, Dutta TK. OP poisoning: predicting the need for ventilatory support. J Assoc Phy India 1998;46:786-9.
24. Malik GM, Mubarik M, Romshoo GJ. Organophosphorus poisoning in the Kashmir valley 1994 to 1997. New Eng J Med 1998;338:1078-9.
25. Eyer P. The role of oximes in the management of organophosphorus pesticide poisoning. Toxic Review 2003;22:165-90.
26. Becker LM. Treatment of acute OP poisoning: evidence of direct effect on CNS by PAM. J Clin Toxic 1982;191:121-7.
27. Johnson S, Peter JV, Thomas K. Evaluation of two treatment regimens of pralidomixe (1 gm single bolus dose Vs 12 gm infusion) in the management of OP poisoning. Arch Intern Med 1994;154:1433-41.
28. Cherian AM, Peter JV, Samuel J, Rajiv J, Peter S, Joyeal S et al. Effectiveness of PAM in treatment of OP poisoning: A randomized double blind placebo-controlled trial. J Assoc Phy Ind 1997;45:20-4.
29. Abdollehi, Jaferi M, Jalali NA. A new approach to the efficacy of oximes in management of acute OP poisoning. Iranian J Med 1995;20:105-9.
30. Chugh SN, Aggarwal N, Dabla S. Comparative evaluation of "atropine alone" and "atropine with pralidoxime (PAM)" in the management of OP poisoning. Int J Crit Care Med 2005;6:33-7.
31. Asari Y, Kamijyo Y, Soma K. Changes in the hemodynamic state of patients with acute lethal organophosphate poisoning. Vet Hum Toxicol 2004;46:5-9
32. Bird S. Organophosphate and carbamate toxicity. Up To Date 2007;15:3.