메뉴 건너뛰기




Volumn 5, Issue 207, 2013, Pages

mAbs and Ad-vectored IFN-α therapy rescue Ebola-infected nonhuman primates when administered after the detection of viremia and symptoms

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ALANINE AMINOTRANSFERASE; ALPHA INTERFERON; ASPARTATE AMINOTRANSFERASE; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 4; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY ZM; UNCLASSIFIED DRUG;

EID: 84886410412     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3006605     Document Type: Article
Times cited : (106)

References (32)
  • 1
    • 0035197291 scopus 로고    scopus 로고
    • Ebola virus: The search for vaccines and treatments
    • J. A. Wilson, C. M. Bosio, M. K. Hart, Ebola virus: The search for vaccines and treatments. Cell. Mol. Life Sci. 58, 1826-1841 (2001).
    • (2001) Cell. Mol. Life Sci. , vol.58 , pp. 1826-1841
    • Wilson, J.A.1    Bosio, C.M.2    Hart, M.K.3
  • 6
    • 35748957479 scopus 로고    scopus 로고
    • Pre- and post-exposure protection against Western equine encephalitis virus after single inoculation with adenovirus vector expressing interferon alpha
    • J. Q. Wu, N. D. Barabé, Y. M. Huang, G. A. Rayner, M. E. Christopher, F. L. Schmaltz, Pre- and post-exposure protection against Western equine encephalitis virus after single inoculation with adenovirus vector expressing interferon alpha. Virology 369, 206-213 (2007).
    • (2007) Virology , vol.369 , pp. 206-213
    • Wu, J.Q.1    Barabé, N.D.2    Huang, Y.M.3    Rayner, G.A.4    Christopher, M.E.5    Schmaltz, F.L.6
  • 8
    • 84880348349 scopus 로고    scopus 로고
    • Monoclonal antibodies combined with adenovirus-vectored interferon significantly extend the treatment window in Ebola virus-infected guinea pigs
    • X. Qiu, G. Wong, L. Fernando, J. Ennis, J. D. Turner, J. B. Alimonti, X. Yao, G. P. Kobinger, Monoclonal antibodies combined with adenovirus-vectored interferon significantly extend the treatment window in Ebola virus-infected guinea pigs. J. Virol. 87, 7754-7757 (2013).
    • (2013) J. Virol. , vol.87 , pp. 7754-7757
    • Qiu, X.1    Wong, G.2    Fernando, L.3    Ennis, J.4    Turner, J.D.5    Alimonti, J.B.6    Yao, X.7    Kobinger, G.P.8
  • 9
    • 0033037010 scopus 로고    scopus 로고
    • An analysis of features of pathogenesis in two animal models of Ebola virus infection
    • E. I. Ryabchikova, L. V. Kolesnikova, S. V. Luchko, An analysis of features of pathogenesis in two animal models of Ebola virus infection. J. Infect. Dis. 179 (Suppl. 1), S199-S202 (1999).
    • (1999) J. Infect. Dis. , vol.179 , Issue.SUPPL. 1
    • Ryabchikova, E.I.1    Kolesnikova, L.V.2    Luchko, S.V.3
  • 10
    • 0024669532 scopus 로고
    • Clinical aspects of African viral hemorrhagic fevers
    • J. H. Gear, Clinical aspects of African viral hemorrhagic fevers. Rev. Infect. Dis. 11 (Suppl. 4), S777-S782 (1989).
    • (1989) Rev. Infect. Dis. , vol.11 , Issue.SUPPL. 4
    • Gear, J.H.1
  • 19
    • 56149115867 scopus 로고    scopus 로고
    • Nasal delivery of an adenovirus-based vaccine bypasses pre-existing immunity to the vaccine carrier and improves the immune response in mice
    • M. A. Croyle, A. Patel, K. N. Tran, M. Gray, Y. Zhang, J. E. Strong, H. Feldmann, G. P. Kobinger, Nasal delivery of an adenovirus-based vaccine bypasses pre-existing immunity to the vaccine carrier and improves the immune response in mice. PLoS One 3, e3548 (2008).
    • (2008) PLoS One , vol.3
    • Croyle, M.A.1    Patel, A.2    Tran, K.N.3    Gray, M.4    Zhang, Y.5    Strong, J.E.6    Feldmann, H.7    Kobinger, G.P.8
  • 20
    • 84875525572 scopus 로고    scopus 로고
    • Airway delivery of an adenovirus-based Ebola virus vaccine bypasses existing immunity to homologous adenovirus in nonhuman primates
    • J. S. Richardson, S. Pillet, A. J. Bello, G. P. Kobinger, Airway delivery of an adenovirus-based Ebola virus vaccine bypasses existing immunity to homologous adenovirus in nonhuman primates. J. Virol. 87, 3668-3677 (2013).
    • (2013) J. Virol. , vol.87 , pp. 3668-3677
    • Richardson, J.S.1    Pillet, S.2    Bello, A.J.3    Kobinger, G.P.4
  • 22
    • 19344366513 scopus 로고    scopus 로고
    • Ebola virus: The role of macrophages and dendritic cells in the pathogenesis of Ebola hemorrhagic fever
    • M. Bray, T. W. Geisbert, Ebola virus: The role of macrophages and dendritic cells in the pathogenesis of Ebola hemorrhagic fever. Int. J. Biochem. Cell Biol. 37, 1560-1566 (2005).
    • (2005) Int. J. Biochem. Cell Biol. , vol.37 , pp. 1560-1566
    • Bray, M.1    Geisbert, T.W.2
  • 24
    • 12344273726 scopus 로고    scopus 로고
    • The blood-brain barrier: Bottleneck in brain drug development
    • W. M. Pardridge, The blood-brain barrier: Bottleneck in brain drug development. NeuroRx 2, 3-14 (2005).
    • (2005) NeuroRx , vol.2 , pp. 3-14
    • Pardridge, W.M.1
  • 26
    • 4544228226 scopus 로고    scopus 로고
    • Analysis of human peripheral blood samples from fatal and nonfatal cases of Ebola (Sudan) hemorrhagic fever: Cellular responses, virus load, and nitric oxide levels
    • A. Sanchez, M. Lukwiya, D. Bausch, S. Mahanty, A. J. Sanchez, K. D. Wagoner, P. E. Rollin, Analysis of human peripheral blood samples from fatal and nonfatal cases of Ebola (Sudan) hemorrhagic fever: Cellular responses, virus load, and nitric oxide levels. J. Virol. 78, 10370-10377 (2004).
    • (2004) J. Virol. , vol.78 , pp. 10370-10377
    • Sanchez, A.1    Lukwiya, M.2    Bausch, D.3    Mahanty, S.4    Sanchez, A.J.5    Wagoner, K.D.6    Rollin, P.E.7
  • 30
    • 65849373288 scopus 로고    scopus 로고
    • Mucosal immunization of cynomolgus macaques with the VSVD G/ZEBOVGP vaccine stimulates strong Ebola GP-specific immune responses
    • X. Qiu, L. Fernando, J. B. Alimonti, P. L. Melito, F. Feldmann, D. Dick, U. Ströher, H. Feldmann, S. M. Jones, Mucosal immunization of cynomolgus macaques with the VSVD G/ZEBOVGP vaccine stimulates strong Ebola GP-specific immune responses. PLoS One 4, e5547 (2009).
    • (2009) PLoS One , vol.4
    • Qiu, X.1    Fernando, L.2    Alimonti, J.B.3    Melito, P.L.4    Feldmann, F.5    Dick, D.6    Ströher, U.7    Feldmann, H.8    Jones, S.M.9
  • 31
    • 33745158157 scopus 로고
    • A simple method of estimating fifty per cent endpoints
    • L. J. Reed, H. Muench, A simple method of estimating fifty per cent endpoints. Am. J. Hyg. 27, 493-497 (1938).
    • (1938) Am. J. Hyg. , vol.27 , pp. 493-497
    • Reed, L.J.1    Muench, H.2
  • 32
    • 0024444791 scopus 로고
    • Isolation and direct complete nucleotide determination of entire genes. Characterization of a gene coding for 16S ribosomal RNA
    • U. Edwards, T. Rogall, H. Blöcker, M. Emde, E. C. Böttger, Isolation and direct complete nucleotide determination of entire genes. Characterization of a gene coding for 16S ribosomal RNA. Nucleic Acids Res. 17, 7843-7853 (1989).
    • (1989) Nucleic Acids Res. , vol.17 , pp. 7843-7853
    • Edwards, U.1    Rogall, T.2    Blöcker, H.3    Emde, M.4    Böttger, E.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.