Generation of Induced Pluripotent Stem Cells with High Efficiency from Human Umbilical Cord Blood Mononuclear Cells

Genomics, Proteomics and Bioinformatics

Volumn 11, Issue 5, 2013, Pages 304-311

  Wang, Juan ^a,b   Gu, Qi ^a   Hao, Jie ^a   Bai, Donghui ^a,c   Liu, Lei ^a   Zhao, Xiaoyang ^a   Liu, Zhonghua ^b   Wang, Liu ^a   Zhou, Qi ^a  

^a INSTITUTE OF ZOOLOGY   (China)

^b NORTHEAST AGRICULTURAL UNIVERSITY   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Dox inducible lentiviral system; Human iPSCs; Human UCBMCs

Indexed keywords

DOXYCYCLINE; MESSENGER RNA;

ARTICLE; CELL DIFFERENTIATION; CELL THERAPY; CONTROLLED STUDY; GENE EXPRESSION; GERM LAYER; HUMAN; HUMAN CELL; LENTIVIRINAE; MONONUCLEAR CELL; NORMAL HUMAN; PLURIPOTENT STEM CELL; REGENERATIVE MEDICINE; UMBILICAL CORD BLOOD MONONUCLEAR CELL;

DOX-INDUCIBLE LENTIVIRAL SYSTEM; HUMAN IPSCS; HUMAN UCBMCS;

BIOLOGICAL MARKERS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL SEPARATION; FETAL BLOOD; GERM LAYERS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; INFANT, NEWBORN; LENTIVIRUS;

EID: 84886390392     PISSN: 16720229     EISSN: 22103244     Source Type: Journal    
DOI: 10.1016/j.gpb.2013.08.002     Document Type: Article

References (36)

1. Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131:861-872.
2. Yu J., Vodyanik M.A., Smuga-Otto K., Antosiewicz-Bourget J., Frane J.L., Tian S., et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007, 318:1917-1920.
3. Warren L., Manos P.D., Ahfeldt T., Loh Y.H., Li H., Lau F., et al. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 2010, 7:618-630.
4. Lowry W.E., Richter L., Yachechko R., Pyle A.D., Tchieu J., Sridharan R., et al. Generation of human induced pluripotent stem cells from dermal fibroblasts. Proc Natl Acad Sci U S A 2008, 105:2883-2888.
5. Park I.H., Zhao R., West J.A., Yabuuchi A., Huo H., Ince T.A., et al. Reprogramming of human somatic cells to pluripotency with defined factors. Nature 2008, 451:141-146.
6. Aasen T., Raya A., Barrero M.J., Garreta E., Consiglio A., Gonzalez F., et al. Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes. Nat Biotechnol 2008, 26:1276-1284.
7. Esteban M.A., Wang T., Qin B., Yang J., Qin D., Cai J., et al. Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. Cell Stem Cell 2010, 6:71-79.
8. Giorgetti A., Montserrat N., Aasen T., Gonzalez F., Rodriguez-Piza I., Vassena R., et al. Generation of induced pluripotent stem cells from human cord blood using OCT4 and SOX2. Cell Stem Cell 2009, 5:353-357.
9. Haase A., Olmer R., Schwanke K., Wunderlich S., Merkert S., Hess C., et al. Generation of induced pluripotent stem cells from human cord blood. Cell Stem Cell 2009, 5:434-441.
10. Nishishita N., Takenaka C., Fusaki N., Kawamata S. Generation of human induced pluripotent stem cells from cord blood cells. J Stem Cells 2011, 6:101-108.
11. Zaehres H., Kogler G., Arauzo-Bravo M.J., Bleidissel M., Santourlidis S., Weinhold S., et al. Induction of pluripotency in human cord blood unrestricted somatic stem cells. Exp Hematol 2010, 38:809-818. 818. e1-2.
12. Takenaka C., Nishishita N., Takada N., Jakt L.M., Kawamata S. Effective generation of iPS cells from CD34+ cord blood cells by inhibition of p53. Exp Hematol 2010, 38:154-162.
13. Chou B.K., Mali P., Huang X., Ye Z., Dowey S.N., Resar L.M., et al. Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Cell Res 2011, 21:518-529.
14. Loh Y.H., Hartung O., Li H., Guo C., Sahalie J.M., Manos P.D., et al. Reprogramming of T cells from human peripheral blood. Cell Stem Cell 2010, 7:15-19.
15. Seki T., Yuasa S., Oda M., Egashira T., Yae K., Kusumoto D., et al. Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells. Cell Stem Cell 2010, 7:11-14.
16. Staerk J., Dawlaty M.M., Gao Q., Maetzel D., Hanna J., Sommer C.A., et al. Reprogramming of human peripheral blood cells to induced pluripotent stem cells. Cell Stem Cell 2010, 7:20-24.
17. Su R.J., Baylink D.J., Neises A., Kiroyan J.B., Meng X., Payne K.J., et al. Efficient generation of integration-free iPS cells from human adult peripheral blood using BCL-XL together with Yamanaka factors. PLoS One 2013, 8:e64496.
18. Sommer A.G., Rozelle S.S., Sullivan S., Mills J.A., Park S.M., Smith B.W., et al. Generation of human induced pluripotent stem cells from peripheral blood using the STEMCCA lentiviral vector. J Vis Exp 2012, pii: 4327. doi: 10.3791/4327.
19. Mack A.A., Kroboth S., Rajesh D., Wang W.B. Generation of induced pluripotent stem cells from CD34+ cells across blood drawn from multiple donors with non-integrating episomal vectors. PLoS One 2011, 6:e27956.
20. Zhou T., Benda C., Duzinger S., Huang Y., Li X., Li Y., et al. Generation of induced pluripotent stem cells from urine. J Am Soc Nephrol 2011, 22:1221-1228.
21. Zhou T., Benda C., Dunzinger S., Huang Y., Ho J.C., Yang J., et al. Generation of human induced pluripotent stem cells from urine samples. Nat Protoc 2012, 7:2080-2089.
22. Abyzov A., Mariani J., Palejev D., Zhang Y., Haney M.S., Tomasini L., et al. Somatic copy number mosaicism in human skin revealed by induced pluripotent stem cells. Nature 2012, 492:438-442.
23. Arnheim N., Cortopassi G. Deleterious mitochondrial DNA mutations accumulate in aging human tissues. Mutat Res 1992, 275:157-167.
24. Ono T., Uehara Y., Saito Y., Ikehata H. Mutation theory of aging, assessed in transgenic mice and knockout mice. Mech Ageing Dev 2002, 123:1543-1552.
25. Hanna J., Markoulaki S., Schorderet P., Carey B.W., Beard C., Wernig M., et al. Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency. Cell 2008, 133:250-264.
26. Huangfu D., Maehr R., Guo W., Eijkelenboom A., Snitow M., Chen A.E., et al. Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat Biotechnol 2008, 26:795-797.
27. Liang G., Taranova O., Xia K., Zhang Y. Butyrate promotes induced pluripotent stem cell generation. J Biol Chem 2010, 285:25516-25521.
28. Shi Y., Desponts C., Do J.T., Hahm H.S., Scholer H.R., Ding S. Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds. Cell Stem Cell 2008, 3:568-574.
29. Wang Q., Xu X., Li J., Liu J., Gu H., Zhang R., et al. Lithium, an anti-psychotic drug, greatly enhances the generation of induced pluripotent stem cells. Cell Res 2011, 21:1424-1435.
30. Tachibana M., Amato P., Sparman M., Gutierrez N.M., Tippner-Hedges R., Ma H., et al. Human embryonic stem cells derived by somatic cell nuclear transfer. Cell 2013, 153:1228-1238.
31. Zhu S., Li W., Zhou H., Wei W., Ambasudhan R., Lin T., et al. Reprogramming of human primary somatic cells by OCT4 and chemical compounds. Cell Stem Cell 2010, 7:651-655.
32. Gu Q., Hao J., Zhao X.Y., Li W., Liu L., Wang L., et al. Rapid conversion of human ESCs into mouse ESC-like pluripotent state by optimizing culture conditions. Protein Cell 2012, 3:71-79.
33. Tong M., Lv Z., Liu L., Zhu H., Zheng Q.Y., Zhao X.Y., et al. Mice generated from tetraploid complementation competent iPS cells show similar developmental features as those from ES cells but are prone to tumorigenesis. Cell Res 2011, 21:1634-1637.
34. Giorgetti A., Montserrat N., Rodriguez-Piza I., Azqueta C., Veiga A., Izpisua Belmonte J.C. Generation of induced pluripotent stem cells from human cord blood cells with only two factors: Oct4 and Sox2. Nat Protoc 2010, 5:811-820.
35. Ying Q.L., Smith A.G. Defined conditions for neural commitment and differentiation. Methods Enzymol 2003, 365:327-341.
36. Thomson J.A., Itskovitz-Eldor J., Shapiro S.S., Waknitz M.A., Swiergiel J.J., Marshall V.S., et al. Embryonic stem cell lines derived from human blastocysts. Science 1998, 282:1145-1147.