Dimorphic HLA-B signal peptides differentially influence HLA-E- and natural killer cell-mediated cytolysis of HIV-1-infected target cells

Clinical and Experimental Immunology

Volumn 174, Issue 3, 2013, Pages 414-423

  Merino, A M ^a,b   Sabbaj, S ^a   Easlick, J ^b   Goepfert, P ^a   Kaslow, R A ^a,b,c,d   Tang, J ^a,b  

^a University of Alabama at Birmingham   (United States)

^b University of Alabama at Birmingham   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d DEPARTMENT OF VETERANS AFFAIRS   (United States)

Author keywords

HIV 1; HLA B; HLA E; Natural killer cell; Signal peptide

Indexed keywords

ANTIGEN P24; HLA ANTIBODY; HLA B ANTIGEN; HLA E ANTIBODY; HLA E ANTIGEN; INTERLEUKIN 2; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; METHIONINE DERIVATIVE; POSITION 2 METHIONINE; POSITION 2 THREONINE; SIGNAL PEPTIDE; THREONINE; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL CULTURE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOLYSIS; FLOW CYTOMETRY; GENOTYPE; HLA B ALLELE; HLA E ALLELE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; MACROPHAGE; MONOCYTE; MONOCYTE DERIVED MACROPHAGE; NATURAL KILLER CELL; NATURAL KILLER CELL MEDIATED CYTOLYSIS; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; SUPERNATANT; TARGET CELL; VIRUS REPLICATION; VIRUS STRAIN;

HIV-1; HLA-B; HLA-E; NATURAL KILLER CELL; SIGNAL PEPTIDE;

CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; HISTOCOMPATIBILITY ANTIGENS CLASS I; HIV CORE PROTEIN P24; HIV INFECTIONS; HIV-1; HLA-B ANTIGENS; HUMANS; KILLER CELLS, NATURAL; MACROPHAGES; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY C; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY D; PROTEIN SORTING SIGNALS;

EID: 84886312967     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/cei.12187     Document Type: Article

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