-
1
-
-
79952232216
-
Global cancer statistics
-
Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin 2011; 61:69-90.
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
2
-
-
1542318323
-
Helicobacter pylori infection and gastric atrophy: Risk of adenocarcinoma and squamous-cell carcinoma of the esophagus and adenocarcinoma of the gastric cardia
-
Ye W, Held M, Lagergren J, et al. Helicobacter pylori infection and gastric atrophy: Risk of adenocarcinoma and squamous-cell carcinoma of the esophagus and adenocarcinoma of the gastric cardia. J Natl Cancer Inst 2004; 96:388-396.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 388-396
-
-
Ye, W.1
Held, M.2
Lagergren, J.3
-
3
-
-
23344432659
-
Cellular mucosal defense during Helicobacter pylori infection: A review of the role of glutathione and the oxidative pentose pathway
-
Matthews GM, Butler RN. Cellular mucosal defense during Helicobacter pylori infection: A review of the role of glutathione and the oxidative pentose pathway. Helicobacter 2005; 10:298-306.
-
(2005)
Helicobacter
, vol.10
, pp. 298-306
-
-
Matthews, G.M.1
Butler, R.N.2
-
4
-
-
0029076049
-
The prevalence of Helicobacter pylori infection in different countries
-
Pounder RE, Ng D. The prevalence of Helicobacter pylori infection in different countries. Aliment Pharmacol Ther 1995; 9:33-39.
-
(1995)
Aliment Pharmacol Ther
, vol.9
, pp. 33-39
-
-
Pounder, R.E.1
Ng, D.2
-
5
-
-
0142117212
-
Smoking and the risk of gastric cancer in the European Prospective Investigation Into Cancer and Nutrition (EPIC)
-
Gonzalez CA, Pera G, Agudo A, et al. Smoking and the risk of gastric cancer in the European Prospective Investigation Into Cancer and Nutrition (EPIC). Int J Cancer 2003; 107:629-634.
-
(2003)
Int J Cancer
, vol.107
, pp. 629-634
-
-
Gonzalez, C.A.1
Pera, G.2
Agudo, A.3
-
6
-
-
33644752905
-
Meat intake and risk of stomach and esophageal adenocarcinoma within the European Prospective Investigation Into Cancer and Nutrition (EPIC)
-
Gonzalez CA, Jakszyn P, Pera G, et al. Meat intake and risk of stomach and esophageal adenocarcinoma within the European Prospective Investigation Into Cancer and Nutrition (EPIC). J Natl Cancer Inst 2006; 98:345-354.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 345-354
-
-
Gonzalez, C.A.1
Jakszyn, P.2
Pera, G.3
-
7
-
-
33646405748
-
Fruit and vegetable intake and the risk of stomach and oesophagus adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST)
-
Gonzalez CA, Pera G, Agudo A, et al. Fruit and vegetable intake and the risk of stomach and oesophagus adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST). Int J Cancer 2006; 118:2559-2566.
-
(2006)
Int J Cancer
, vol.118
, pp. 2559-2566
-
-
Gonzalez, C.A.1
Pera, G.2
Agudo, A.3
-
8
-
-
17944386992
-
Body mass index and risk of adenocarcinomas of the esophagus and gastric cardia
-
Chow WH, Blot WJ, Vaughan TL, et al. Body mass index and risk of adenocarcinomas of the esophagus and gastric cardia. J Natl Cancer Inst 1998; 90:150-155.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 150-155
-
-
Chow, W.H.1
Blot, W.J.2
Vaughan, T.L.3
-
9
-
-
11144260117
-
Prospective study of risk factors for esophageal and gastric cancers in the Linxian general population trial cohort in China
-
Tran GD, Sun XD, Abnet CC, et al. Prospective study of risk factors for esophageal and gastric cancers in the Linxian general population trial cohort in China. Int J Cancer 2005; 113:456-463.
-
(2005)
Int J Cancer
, vol.113
, pp. 456-463
-
-
Tran, G.D.1
Sun, X.D.2
Abnet, C.C.3
-
10
-
-
0036632368
-
The phosphatidylinositol 3-Kinase AKT pathway in human cancer
-
Vivanco I, Sawyers CL. The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer 2002; 2:489-501.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
11
-
-
32044465506
-
TOR signaling in growth and metabolism
-
Wullschleger S, Loewith R, Hall MN. TOR signaling in growth and metabolism. Cell 2006; 124:471-484.
-
(2006)
Cell
, vol.124
, pp. 471-484
-
-
Wullschleger, S.1
Loewith, R.2
Hall, M.N.3
-
12
-
-
3242721268
-
mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells
-
Murakami M, Ichisaka T, Maeda M, et al. mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells. Mol Cell Biol 2004; 24:6710-6718.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 6710-6718
-
-
Murakami, M.1
Ichisaka, T.2
Maeda, M.3
-
13
-
-
6344245674
-
Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development
-
Gangloff YG, Mueller M, Dann SG, et al. Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development. Mol Cell Biol 2004; 24:9508-9516.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 9508-9516
-
-
Gangloff, Y.G.1
Mueller, M.2
Dann, S.G.3
-
14
-
-
34547907805
-
Expanding mTOR signaling
-
Yang Q, Guan KL. Expanding mTOR signaling. Cell Res 2007; 17:666-681.
-
(2007)
Cell Res
, vol.17
, pp. 666-681
-
-
Yang, Q.1
Guan, K.L.2
-
15
-
-
0037623417
-
GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR
-
Kim DH, Sarbassov DD, Ali SM, et al. GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR. Mol Cell 2003; 11:895-904.
-
(2003)
Mol Cell
, vol.11
, pp. 895-904
-
-
Kim, D.H.1
Sarbassov, D.D.2
Ali, S.M.3
-
16
-
-
11244297916
-
Dysregulation of the TSC-mTOR pathway in human disease
-
Inoki K, Corradetti MN, Guan KL. Dysregulation of the TSC-mTOR pathway in human disease. Nat Genet 2005; 37:19-24.
-
(2005)
Nat Genet
, vol.37
, pp. 19-24
-
-
Inoki, K.1
Corradetti, M.N.2
Guan, K.L.3
-
17
-
-
60849109531
-
Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy
-
Hildebrandt MA, Yang H, Hung MC, et al. Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy. J Clin Oncol 2009; 27:857-871.
-
(2009)
J Clin Oncol
, vol.27
, pp. 857-871
-
-
Hildebrandt, M.A.1
Yang, H.2
Hung, M.C.3
-
18
-
-
73949109246
-
Genetic variations in PI3K-AKT-mTOR pathway and bladder cancer risk
-
Chen M, Cassidy A, Gu J, et al. Genetic variations in PI3K-AKT-mTOR pathway and bladder cancer risk. Carcinogenesis 2009; 30:2047-2052.
-
(2009)
Carcinogenesis
, vol.30
, pp. 2047-2052
-
-
Chen, M.1
Cassidy, A.2
Gu, J.3
-
19
-
-
77950838851
-
Energy balance, the PI3K-AKT-mTOR pathway genes, and the risk of bladder cancer
-
Lin J, Wang J, Greisinger AJ, et al. Energy balance, the PI3K-AKT-mTOR pathway genes, and the risk of bladder cancer. Cancer Prev Res (Phila) 2010; 3:505-517.
-
(2010)
Cancer Prev Res (Phila)
, vol.3
, pp. 505-517
-
-
Lin, J.1
Wang, J.2
Greisinger, A.J.3
-
20
-
-
77956288187
-
Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1
-
Slattery ML, Herrick JS, Lundgreen A, Fitzpatrick FA, Curtin K, Wolff RK. Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1. Carcinogenesis 2010; 31:1604-1611.
-
(2010)
Carcinogenesis
, vol.31
, pp. 1604-1611
-
-
Slattery, M.L.1
Herrick, J.S.2
Lundgreen, A.3
Fitzpatrick, F.A.4
Curtin, K.5
Wolff, R.K.6
-
21
-
-
84862773697
-
Polymorphisms in the XPG gene and risk of gastric cancer in Chinese populations
-
He J, Qiu LX, Wang MY, et al. Polymorphisms in the XPG gene and risk of gastric cancer in Chinese populations. Hum Genet 2012; 131:1235-1244.
-
(2012)
Hum Genet
, vol.131
, pp. 1235-1244
-
-
He, J.1
Qiu, L.X.2
Wang, M.Y.3
-
22
-
-
84869227080
-
Polymorphisms in ERCC1 and XPF genes and risk of gastric cancer in an eastern Chinese population
-
He J, Xu Y, Qiu LX, et al. Polymorphisms in ERCC1 and XPF genes and risk of gastric cancer in an eastern Chinese population. PLoS ONE 2012; 7:e49308.
-
(2012)
PLoS ONE
, vol.7
-
-
He, J.1
Xu, Y.2
Qiu, L.X.3
-
23
-
-
78650993111
-
7th edition of the AJCC cancer staging manual: Stomach
-
Washington K. 7th edition of the AJCC cancer staging manual: Stomach. Ann Surg Oncol 2010; 17:3077-3079.
-
(2010)
Ann Surg Oncol
, vol.17
, pp. 3077-3079
-
-
Washington, K.1
-
24
-
-
68049137338
-
Rationales, design and recruitment of the Taizhou longitudinal study
-
Wang X, Lu M, Qian J, et al. Rationales, design and recruitment of the Taizhou longitudinal study. BMC Public Health 2009; 9:223.
-
(2009)
BMC Public Health
, vol.9
, pp. 223
-
-
Wang, X.1
Lu, M.2
Qian, J.3
-
25
-
-
0034973569
-
Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer
-
Ritchie MD, Hahn LW, Roodi N, et al. Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer. Am J Hum Genet 2001; 69:138-147.
-
(2001)
Am J Hum Genet
, vol.69
, pp. 138-147
-
-
Ritchie, M.D.1
Hahn, L.W.2
Roodi, N.3
-
26
-
-
1642295096
-
Assessing the probability that a positive report is false: An approach for molecular epidemiology studies
-
Wacholder S, Chanock S, Garcia-Closas M, El Ghormli L, Rothman N. Assessing the probability that a positive report is false: An approach for molecular epidemiology studies. J Natl Cancer Inst 2004; 96:434-442.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 434-442
-
-
Wacholder, S.1
Chanock, S.2
Garcia-Closas, M.3
El Ghormli, L.4
Rothman, N.5
-
27
-
-
0034644525
-
TOR, a central controller of cell growth
-
Schmelzle T, Hall MN. TOR, a central controller of cell growth. Cell 2000; 103:253-262.
-
(2000)
Cell
, vol.103
, pp. 253-262
-
-
Schmelzle, T.1
Hall, M.N.2
-
28
-
-
0028800996
-
PIK-related kinases: DNA repair, recombination, and cell cycle checkpoints
-
Keith CT, Schreiber SL. PIK-related kinases: DNA repair, recombination, and cell cycle checkpoints. Science 1995; 270:50-51.
-
(1995)
Science
, vol.270
, pp. 50-51
-
-
Keith, C.T.1
Schreiber, S.L.2
-
29
-
-
0037600512
-
Schizosaccharomyces pombe AGC family kinase Gad8p forms a conserved signaling module with TOR and PDK1-like kinases
-
Matsuo T, Kubo Y, Watanabe Y, Yamamoto M. Schizosaccharomyces pombe AGC family kinase Gad8p forms a conserved signaling module with TOR and PDK1-like kinases. EMBO J 2003; 22:3073-3083.
-
(2003)
EMBO J
, vol.22
, pp. 3073-3083
-
-
Matsuo, T.1
Kubo, Y.2
Watanabe, Y.3
Yamamoto, M.4
-
30
-
-
72949083368
-
Common corruption of the mTOR signaling network in human tumors
-
Menon S, Manning BD. Common corruption of the mTOR signaling network in human tumors. Oncogene 2008; 27:S43-S51.
-
(2008)
Oncogene
, vol.27
-
-
Menon, S.1
Manning, B.D.2
-
31
-
-
34250788809
-
AKT/PKB signaling: Navigating downstream
-
Manning BD, Cantley LC. AKT/PKB signaling: Navigating downstream. Cell 2007; 129:1261-1274.
-
(2007)
Cell
, vol.129
, pp. 1261-1274
-
-
Manning, B.D.1
Cantley, L.C.2
-
33
-
-
78651359460
-
PI3K/PTEN/AKT/mTOR pathway genetic variation predicts toxicity and distant progression in lung cancer patients receiving platinum-based chemotherapy
-
Pu X, Hildebrandt MA, Lu C, et al. PI3K/PTEN/AKT/mTOR pathway genetic variation predicts toxicity and distant progression in lung cancer patients receiving platinum-based chemotherapy. Lung Cancer 2011; 71:82-88.
-
(2011)
Lung Cancer
, vol.71
, pp. 82-88
-
-
Pu, X.1
Hildebrandt, M.A.2
Lu, C.3
-
34
-
-
79952602647
-
Clinical significance of genetic variations in the PI3K/PTEN/AKT/mTOR pathway in Korean patients with colorectal cancer
-
Kim JG, Chae YS, Sohn SK, et al. Clinical significance of genetic variations in the PI3K/PTEN/AKT/mTOR pathway in Korean patients with colorectal cancer. Oncology 2010; 79:278-282.
-
(2010)
Oncology
, vol.79
, pp. 278-282
-
-
Kim, J.G.1
Chae, Y.S.2
Sohn, S.K.3
-
35
-
-
77955390999
-
Genetic variations of the PI3K-AKT-mTOR pathway and clinical outcome in muscle invasive and metastatic bladder cancer patients
-
Chen M, Gu J, Delclos GL, et al. Genetic variations of the PI3K-AKT-mTOR pathway and clinical outcome in muscle invasive and metastatic bladder cancer patients. Carcinogenesis 2010; 31:1387-1391.
-
(2010)
Carcinogenesis
, vol.31
, pp. 1387-1391
-
-
Chen, M.1
Gu, J.2
Delclos, G.L.3
-
36
-
-
0037178786
-
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
-
Kim DH, Sarbassov DD, Ali SM, et al. mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 2002; 110:163-175.
-
(2002)
Cell
, vol.110
, pp. 163-175
-
-
Kim, D.H.1
Sarbassov, D.D.2
Ali, S.M.3
-
37
-
-
84859940689
-
Association of genetic variations in mTOR with risk of childhood acute lymphoblastic leukemia in a Chinese population
-
Huang L, Huang J, Wu P, et al. Association of genetic variations in mTOR with risk of childhood acute lymphoblastic leukemia in a Chinese population. Leuk Lymphoma 2012; 53:947-951.
-
(2012)
Leuk Lymphoma
, vol.53
, pp. 947-951
-
-
Huang, L.1
Huang, J.2
Wu, P.3
-
38
-
-
12544257790
-
Nucleotide excision repair as a marker for susceptibility to tobacco-related cancers: A review of molecular epidemiological studies
-
Neumann AS, Sturgis EM, Wei Q. Nucleotide excision repair as a marker for susceptibility to tobacco-related cancers: A review of molecular epidemiological studies. Mol Carcinog 2005; 42:65-92.
-
(2005)
Mol Carcinog
, vol.42
, pp. 65-92
-
-
Neumann, A.S.1
Sturgis, E.M.2
Wei, Q.3
-
39
-
-
0030777204
-
Tobacco, alcohol, and socioeconomic status and adenocarcinomas of the esophagus and gastric cardia
-
Gammon MD, Schoenberg JB, Ahsan H, et al. Tobacco, alcohol, and socioeconomic status and adenocarcinomas of the esophagus and gastric cardia. J Natl Cancer Inst 1997; 89:1277-1284.
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 1277-1284
-
-
Gammon, M.D.1
Schoenberg, J.B.2
Ahsan, H.3
-
40
-
-
0036370334
-
Helicobacter pylori and gastrointestinal tract adenocarcinomas
-
Peek RM, Jr., Blaser MJ. Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nat Rev Cancer 2002; 2:28-37.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 28-37
-
-
Peek Jr, R.M.1
Blaser, M.J.2
|