-
1
-
-
79951847989
-
Principles and current strategies for targeting autophagy for cancer treatment
-
Amaravadi, R.K., Lippincott-Schwartz, J., Yin, X.M., Weiss, W.A., Takebe, N., Timmer, W., DiPaola, R.S., Lotze, M.T., and White, E. (2011). Principles and current strategies for targeting autophagy for cancer treatment. Clin. Cancer Res. 17:654-666. Review.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 654-666
-
-
Amaravadi, R.K.1
Lippincott-Schwartz, J.2
Yin, X.M.3
Weiss, W.A.4
Takebe, N.5
Timmer, W.6
DiPaola, R.S.7
Lotze, M.T.8
White, E.9
-
2
-
-
84864385373
-
Autophagy: friend or foe in breast cancer development, progression, and treatment
-
Berardi, D.E., Campodónico, P.B., Díaz Bessone, M.I., Urtreger, A.J., and Todaro, L.B. (2011). Autophagy: friend or foe in breast cancer development, progression, and treatment. Int. J. Breast Cancer 2011:595092. Review.
-
(2011)
Int. J. Breast Cancer
, vol.2011
, pp. 595092
-
-
Berardi, D.E.1
Campodónico, P.B.2
Díaz Bessone, M.I.3
Urtreger, A.J.4
Todaro, L.B.5
-
3
-
-
0030426282
-
The effects of mibefradil, a novel calcium channel antagonist on ventricular arrhythmias induced by myocardial ischemia and programmed electrical stimulation
-
Billman, G.E., and Hamlin, R.L. (1996). The effects of mibefradil, a novel calcium channel antagonist on ventricular arrhythmias induced by myocardial ischemia and programmed electrical stimulation. J. Pharmacol. Exp. Ther. 277, 1517-1526.
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.277
, pp. 1517-1526
-
-
Billman, G.E.1
Hamlin, R.L.2
-
4
-
-
19944434059
-
Inhibition of macroautophagy triggers apoptosis
-
Boya, P., González-Polo, R.A., Casares, N. et al. (2005). Inhibition of macroautophagy triggers apoptosis. Mol. Cell. Biol. 25, 1025-1040.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 1025-1040
-
-
Boya, P.1
González-Polo, R.A.2
Casares, N.3
-
5
-
-
84864389175
-
Autophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibition
-
Bray, K., Mathew, R., Lau, A. et al. (2012). Autophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibition. PLoS ONE 7, e41831.
-
(2012)
PLoS ONE
, vol.7
-
-
Bray, K.1
Mathew, R.2
Lau, A.3
-
6
-
-
0033587675
-
Mammalian unfolded protein response inhibits Cyclin D1 translation and cell cycle progression
-
Brewer, J.W., Hendershot, L.M., Sherr, C.J., and Diehl, J.A. (1999). Mammalian unfolded protein response inhibits Cyclin D1 translation and cell cycle progression. Proc. Natl Acad. Sci. U S A 96, 8505-8510.
-
(1999)
Proc. Natl Acad. Sci. U S A
, vol.96
, pp. 8505-8510
-
-
Brewer, J.W.1
Hendershot, L.M.2
Sherr, C.J.3
Diehl, J.A.4
-
7
-
-
80855130878
-
Cell proliferation, calcium influx and calcium channels
-
Capiod, T. (2011). Cell proliferation, calcium influx and calcium channels. Biochimie 93:2075-2079. Review.
-
(2011)
Biochimie
, vol.93
, pp. 2075-2079
-
-
Capiod, T.1
-
8
-
-
82055185038
-
The gluttonous side of malignant melanoma: basic and clinical implications of macroautophagy
-
Checinska, A., and Soengas, M.S. (2011). The gluttonous side of malignant melanoma: basic and clinical implications of macroautophagy. Pigment Cell Melanoma Res. 24:1116-1132. Review.
-
(2011)
Pigment Cell Melanoma Res
, vol.24
, pp. 1116-1132
-
-
Checinska, A.1
Soengas, M.S.2
-
9
-
-
0032249498
-
Inhibition of T-type voltage-gated calcium channels by a new scorpion toxin
-
Chuang, R.S., Jaffe, H., Cribbs, L., Perez-Reyes, E., and Swartz, K.J. (1998). Inhibition of T-type voltage-gated calcium channels by a new scorpion toxin. Nat. Neurosci. 1, 668-674.
-
(1998)
Nat. Neurosci.
, vol.1
, pp. 668-674
-
-
Chuang, R.S.1
Jaffe, H.2
Cribbs, L.3
Perez-Reyes, E.4
Swartz, K.J.5
-
10
-
-
84857443032
-
Functional expression of voltage-gated calcium channels in human melanoma
-
Das, A., Pushparaj, C., Bahí, N., Sorolla, A., Herreros, J., Pamplona, R., Vilella, R., Matias-Guiu, X., Martí, R.M., and Cantí, C. (2012). Functional expression of voltage-gated calcium channels in human melanoma. Pigment Cell Melanoma Res. 25, 200-212.
-
(2012)
Pigment Cell Melanoma Res.
, vol.25
, pp. 200-212
-
-
Das, A.1
Pushparaj, C.2
Bahí, N.3
Sorolla, A.4
Herreros, J.5
Pamplona, R.6
Vilella, R.7
Matias-Guiu, X.8
Martí, R.M.9
Cantí, C.10
-
11
-
-
0036449524
-
Selectivity of different calcium antagonists on T- and L-type calcium currents in guinea-pig ventricular myocytes
-
De Paoli, P., Cerbai, E., Koidl, B., Kirchengast, M., Sartiani, L., and Mugelli, A. (2002). Selectivity of different calcium antagonists on T- and L-type calcium currents in guinea-pig ventricular myocytes. Pharmacol. Res. 46, 491-497.
-
(2002)
Pharmacol. Res.
, vol.46
, pp. 491-497
-
-
De Paoli, P.1
Cerbai, E.2
Koidl, B.3
Kirchengast, M.4
Sartiani, L.5
Mugelli, A.6
-
12
-
-
33745370071
-
The pharmacology and regulation of T type calcium channels: new opportunities for unique therapeutics for cancer
-
Gray, L.S., and Macdonald, T.L. (2006). The pharmacology and regulation of T type calcium channels: new opportunities for unique therapeutics for cancer. Cell Calcium 40, 115-120. Review.
-
(2006)
Cell Calcium
, vol.40
, pp. 115-120
-
-
Gray, L.S.1
Macdonald, T.L.2
-
13
-
-
33847220364
-
Melanoma biology and new targeted therapy
-
Gray-Schopfer, V., Wellbrock, C., and Marais, R. (2007). Melanoma biology and new targeted therapy. Nature, 445: 851-857. Review.
-
(2007)
Nature
, vol.445
, pp. 851-857
-
-
Gray-Schopfer, V.1
Wellbrock, C.2
Marais, R.3
-
15
-
-
0033634654
-
Regulated translation initiation controls stress-induced gene expression in mammalian cells
-
Harding, H.P., Novoa, I., Zhang, Y., Zeng, H., Wek, R., Schapira, M., and Ron, D. (2000). Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol. Cell 6, 1099-1108.
-
(2000)
Mol. Cell
, vol.6
, pp. 1099-1108
-
-
Harding, H.P.1
Novoa, I.2
Zhang, Y.3
Zeng, H.4
Wek, R.5
Schapira, M.6
Ron, D.7
-
16
-
-
43549087613
-
Adaptation to ER stress as a driver of malignancy and resistance to therapy in human melanoma
-
Hersey, P., Zhang, X.D. (2008). Adaptation to ER stress as a driver of malignancy and resistance to therapy in human melanoma. Pigment Cell Melanoma Res., 21, 358-367. Review.
-
(2008)
Pigment Cell Melanoma Res.
, vol.21
, pp. 358-367
-
-
Hersey, P.1
Zhang, X.D.2
-
17
-
-
34548037901
-
Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium
-
Høyer-Hansen, M., Jäättelä, M. (2007). Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium. Cell Death Diff. 14:1576-1582. Review.
-
(2007)
Cell Death Diff
, vol.14
, pp. 1576-1582
-
-
Høyer-Hansen, M.1
Jäättelä, M.2
-
18
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
Kabeya, Y., Mizushima, N., Ueno, T., Yamamoto, A., Kirisako, T., Noda, T., Komimami, E., Ohsumi, Y., and Yoshimori, T. (2000). LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J. 19, 5720-5728.
-
(2000)
EMBO J.
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
Mizushima, N.2
Ueno, T.3
Yamamoto, A.4
Kirisako, T.5
Noda, T.6
Komimami, E.7
Ohsumi, Y.8
Yoshimori, T.9
-
19
-
-
77955789211
-
Altered lipid content inhibits autophagic vesicular fusion
-
Koga, H., Kaushik, S., and Cuervo, A.M. (2010). Altered lipid content inhibits autophagic vesicular fusion. FASEB J. 24, 3052-3065.
-
(2010)
FASEB J.
, vol.24
, pp. 3052-3065
-
-
Koga, H.1
Kaushik, S.2
Cuervo, A.M.3
-
20
-
-
36849089101
-
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice
-
Komatsu, M., Waguri, S., Koike, M. et al. (2007). Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice. Cell 131, 1149-1163.
-
(2007)
Cell
, vol.131
, pp. 1149-1163
-
-
Komatsu, M.1
Waguri, S.2
Koike, M.3
-
21
-
-
0032547751
-
The short life and rapid death of a novel antihypertensive and antianginal agent
-
Krum, H., and McNeil, J.J. (1998). The short life and rapid death of a novel antihypertensive and antianginal agent. Med. J. Aust. 169, 408-409.
-
(1998)
Med. J. Aust.
, vol.169
, pp. 408-409
-
-
Krum, H.1
McNeil, J.J.2
-
22
-
-
0020061924
-
Effects of dopamine agonists and antagonists on murine melanoma: correlation with dopamine binding activity
-
Krummel, T.M., Neifeld, J.P., and Taub, R.N. (1982). Effects of dopamine agonists and antagonists on murine melanoma: correlation with dopamine binding activity. Cancer 49, 1178-1184.
-
(1982)
Cancer
, vol.49
, pp. 1178-1184
-
-
Krummel, T.M.1
Neifeld, J.P.2
Taub, R.N.3
-
23
-
-
79951857650
-
Unfolded protein response in cancer: the physician's perspective
-
Li, X., Zhang, K., and Li, Z. (2011a). Unfolded protein response in cancer: the physician's perspective. J. Hematol Oncol. 4:8. Review.
-
(2011)
J. Hematol Oncol
, vol.4
, pp. 8
-
-
Li, X.1
Zhang, K.2
Li, Z.3
-
24
-
-
79957508250
-
Blockade of T-type Ca(2+) channels inhibits human ovarian cancer cell proliferation
-
Li, W., Zhang, S.L., Wang, N., Zhang, B.B., and Li, M. (2011b). Blockade of T-type Ca(2+) channels inhibits human ovarian cancer cell proliferation. Cancer Invest. 29, 339-346.
-
(2011)
Cancer Invest.
, vol.29
, pp. 339-346
-
-
Li, W.1
Zhang, S.L.2
Wang, N.3
Zhang, B.B.4
Li, M.5
-
26
-
-
10644251635
-
Pimozide in dermatologic practice: a comprehensive review
-
Lorenzo, C.R., and Koo, J. (2004). Pimozide in dermatologic practice: a comprehensive review. Am. J. Clin. Dermatol. 5, 339-349. Review.
-
(2004)
Am. J. Clin. Dermatol.
, vol.5
, pp. 339-349
-
-
Lorenzo, C.R.1
Koo, J.2
-
27
-
-
79956003662
-
Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma
-
Ma, X.H., Piao, S., Wang, D., McAfee, Q.W., Nathanson, K.L., Lum, J.J., Li, L.Z., and Amaravadi, R.K. (2011). Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma. Clin. Cancer Res. 17, 3478-3489.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 3478-3489
-
-
Ma, X.H.1
Piao, S.2
Wang, D.3
McAfee, Q.W.4
Nathanson, K.L.5
Lum, J.J.6
Li, L.Z.7
Amaravadi, R.K.8
-
28
-
-
79958759965
-
Proton pump inhibition induces autophagy as a survival mechanism following oxidative stress in human melanoma cells
-
Marino, M.L., Fais, S., Djavaheri-Mergny, M. et al. (2010 Oct 21). Proton pump inhibition induces autophagy as a survival mechanism following oxidative stress in human melanoma cells. Cell Death Dis. 1, e87.
-
(2010)
Cell Death Dis
, vol.1
-
-
Marino, M.L.1
Fais, S.2
Djavaheri-Mergny, M.3
-
29
-
-
84865800743
-
Autophagy is a protective mechanism for human melanoma cells under acidic stress
-
Marino, M.L., Pellegrini, P., Di Lernia, G. et al. (2012). Autophagy is a protective mechanism for human melanoma cells under acidic stress. J. Biol. Chem. 287, 30664-30676.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 30664-30676
-
-
Marino, M.L.1
Pellegrini, P.2
Di Lernia, G.3
-
30
-
-
0033803221
-
Mibefradil block of cloned T-type calcium channels
-
Martin, R.L., Lee, J.H., Cribbs, L.L., Pérez-Reyes, E., and Hanck, D.A. (2000). Mibefradil block of cloned T-type calcium channels. J. Pharmacol. Exp. Ther. 295, 302-308.
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.295
, pp. 302-308
-
-
Martin, R.L.1
Lee, J.H.2
Cribbs, L.L.3
Pérez-Reyes, E.4
Hanck, D.A.5
-
31
-
-
0031800773
-
Mibefradil, a T-type channel-selective calcium antagonist: clinical trials in chronic stable angina pectoris
-
Massie, B.M. (1998). Mibefradil, a T-type channel-selective calcium antagonist: clinical trials in chronic stable angina pectoris. Am. J. Hypertens. 11(4 Pt 3):95S-102S. Review.
-
(1998)
Am. J. Hypertens.
, vol.11
, Issue.4 PART 3
-
-
Massie, B.M.1
-
32
-
-
9444260424
-
State-dependent mibefradil block of Na+ channels
-
McNulty, M.M., and Hanck, D.A. (2004). State-dependent mibefradil block of Na+ channels. Mol. Pharmacol. 66, 1652-1661.
-
(2004)
Mol. Pharmacol.
, vol.66
, pp. 1652-1661
-
-
McNulty, M.M.1
Hanck, D.A.2
-
34
-
-
35848967804
-
How to interpret LC3 immunoblotting
-
Mizushima, N., and Yoshimori, T. (2007). How to interpret LC3 immunoblotting. Autophagy 3, 542-545.
-
(2007)
Autophagy
, vol.3
, pp. 542-545
-
-
Mizushima, N.1
Yoshimori, T.2
-
35
-
-
66449114033
-
P62 at the crossroads of autophagy, apoptosis and cancer
-
Moscat, J., and Díaz-Meco, M.T. (2009). P62 at the crossroads of autophagy, apoptosis and cancer. Cell 137, 1001-1004. Review.
-
(2009)
Cell
, vol.137
, pp. 1001-1004
-
-
Moscat, J.1
Díaz-Meco, M.T.2
-
37
-
-
33845459165
-
Autophagy is activated for cell survival after endoplasmic reticulum stress
-
Ogata, M., Hino, S., Saito, A. et al. (2006). Autophagy is activated for cell survival after endoplasmic reticulum stress. Mol. Cell. Biol. 24, 9220-9231.
-
(2006)
Mol. Cell. Biol.
, vol.24
, pp. 9220-9231
-
-
Ogata, M.1
Hino, S.2
Saito, A.3
-
38
-
-
0035823579
-
Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation
-
Rao, R.V., Hermel, E., Castro-Obregón, S., Del Río, G., Ellerby, L.M., Ellerby, H.M., and Bredesen, D.E. (2001). Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation. J. Biol. Chem. 276, 33869-33874.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 33869-33874
-
-
Rao, R.V.1
Hermel, E.2
Castro-Obregón, S.3
Del Río, G.4
Ellerby, L.M.5
Ellerby, H.M.6
Bredesen, D.E.7
-
39
-
-
33745410655
-
T channels and steroid biosynthesis: in search of a link with mitochondria
-
Rossier, M.F. (2006). T channels and steroid biosynthesis: in search of a link with mitochondria. Cell Calcium 40, 155-164.
-
(2006)
Cell Calcium
, vol.40
, pp. 155-164
-
-
Rossier, M.F.1
-
40
-
-
35348827324
-
That which does not kill me makes me stronger: adapting to chronic ER stress
-
Rutkowski, D.T., and Kaufman, R.J. (2007). That which does not kill me makes me stronger: adapting to chronic ER stress. Trends Biochem. Sci. 32:469-476. Review.
-
(2007)
Trends Biochem. Sci.
, vol.32
, pp. 469-476
-
-
Rutkowski, D.T.1
Kaufman, R.J.2
-
41
-
-
0037079997
-
Differential inhibition of T-type calcium channels by neuroleptics
-
Santi, C.M., Cayabyab, F.S., Sutton, K.G., McRory, J.E., Mezeyova, J., Hamming, K.S., Parker, D., Stea, A., and Snutch, T.P. (2002). Differential inhibition of T-type calcium channels by neuroleptics. J. Neurosci. 22, 396-403.
-
(2002)
J. Neurosci.
, vol.22
, pp. 396-403
-
-
Santi, C.M.1
Cayabyab, F.S.2
Sutton, K.G.3
McRory, J.E.4
Mezeyova, J.5
Hamming, K.S.6
Parker, D.7
Stea, A.8
Snutch, T.P.9
-
42
-
-
84861326960
-
Functional role of T-type calcium channels in tumour growth and progression: prospective in cancer therapy
-
Santoni, G., Santoni, M., and Nabissi, M. (2012). Functional role of T-type calcium channels in tumour growth and progression: prospective in cancer therapy. Br. J. Pharmacol. 166, 1244-1246. Review.
-
(2012)
Br. J. Pharmacol.
, vol.166
, pp. 1244-1246
-
-
Santoni, G.1
Santoni, M.2
Nabissi, M.3
-
43
-
-
0034973982
-
Translational control is required for the unfolded protein response and in vivo glucose homeostasis
-
Scheuner, D., Song, B., McEwen, E., Liu, C., Laybutt, R., Gillespie, P., Saunders, T., Bonner-Weir, S., and Kaufman, R.J. (2001). Translational control is required for the unfolded protein response and in vivo glucose homeostasis. Mol. Cell 7, 1165-1176.
-
(2001)
Mol. Cell
, vol.7
, pp. 1165-1176
-
-
Scheuner, D.1
Song, B.2
McEwen, E.3
Liu, C.4
Laybutt, R.5
Gillespie, P.6
Saunders, T.7
Bonner-Weir, S.8
Kaufman, R.J.9
-
44
-
-
45849103510
-
2+ channels suppresses human breast cancer cell proliferation
-
2+ channels suppresses human breast cancer cell proliferation. Cancer Lett. 267, 116-124.
-
(2008)
Cancer Lett.
, vol.267
, pp. 116-124
-
-
Taylor, J.T.1
Huang, L.2
Pottle, J.E.3
Liu, K.4
Yang, Y.5
Zeng, X.6
Keyser, B.M.7
Agrawal, K.C.8
Hansen, J.B.9
Li, M.10
-
45
-
-
77955947900
-
Linking ER stress to autophagy: potential implications for cancer therapy
-
Verfaillie, T., Salazar, M., Velasco, G., and Agostinis, P. (2010). Linking ER stress to autophagy: potential implications for cancer therapy. Int. J. Cell Biol. 2010: 930509. Review.
-
(2010)
Int. J. Cell Biol.
, vol.2010
, pp. 930509
-
-
Verfaillie, T.1
Salazar, M.2
Velasco, G.3
Agostinis, P.4
-
46
-
-
84864878269
-
Crosstalk between the UPR and autophagy pathway contributes to handling cellular stress in neurodegenerative disease
-
Vidal, R.L., and Hetz, C. (2012). Crosstalk between the UPR and autophagy pathway contributes to handling cellular stress in neurodegenerative disease. Autophagy. 8, 970-972.
-
(2012)
Autophagy.
, vol.8
, pp. 970-972
-
-
Vidal, R.L.1
Hetz, C.2
-
47
-
-
77953387854
-
Endoplasmic reticulum stress response in cancer: molecular mechanism and therapeutic potential
-
Wang, G., Yang, Z.Q., and Zhang, K. (2010). Endoplasmic reticulum stress response in cancer: molecular mechanism and therapeutic potential. Am. J. Transl. Res. 2, 65-74.
-
(2010)
Am. J. Transl. Res.
, vol.2
, pp. 65-74
-
-
Wang, G.1
Yang, Z.Q.2
Zhang, K.3
-
48
-
-
33845535111
-
Melanomas arising from naevi and de novo melanomas-does origin matter?
-
Weatherhead, S.C., Haniffa, M., and Lawrence, C.M. (2007). Melanomas arising from naevi and de novo melanomas-does origin matter? Br. J. Dermatol. 156, 72-76. Review.
-
(2007)
Br. J. Dermatol.
, vol.156
, pp. 72-76
-
-
Weatherhead, S.C.1
Haniffa, M.2
Lawrence, C.M.3
-
49
-
-
80052697287
-
The role of autophagy in cancer: therapeutic implications
-
Yang, Z.J., Chee, C.E., Huang, S., and Sinicrope, F.A. (2011). The role of autophagy in cancer: therapeutic implications. Mol. Cancer Ther. 10, 1533-1541.
-
(2011)
Mol. Cancer Ther.
, vol.10
, pp. 1533-1541
-
-
Yang, Z.J.1
Chee, C.E.2
Huang, S.3
Sinicrope, F.A.4
-
50
-
-
33749579383
-
Endoplasmic reticulum stress triggers autophagy
-
Yorimitsu, T., Nair, U., Yang, Z., and Klionsly, D.J. (2006). Endoplasmic reticulum stress triggers autophagy. J. Biol. Chem. 281, 30299-30304.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 30299-30304
-
-
Yorimitsu, T.1
Nair, U.2
Yang, Z.3
Klionsly, D.J.4
|