Determination of monoamine and amino acid neurotransmitters and their metabolites in rat brain samples by UFLC-MS/MS for the study of the sedative-hypnotic effects observed during treatment with S. chinensis

Journal of Pharmaceutical and Biomedical Analysis

Volumn 88, Issue , 2014, Pages 416-422

  Wei, Binbin ^a,b   Li, Qing ^a   Fan, Ronghua ^a   Su, Dan ^c   Chen, Xiaohui ^a   Jia, Ying ^a,b   Bi, Kaishun ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b Shenyang Key Laboratory of Active Components of Chinese Medicine Screening and Evaluation   (China)

^c Jiangxi University of Chinese Traditional Medicine   (China)

Author keywords

Brain samples; Neurotransmitters; Schisandra chinensis (Turcz.); Sedative and hypnotic; UFLC MS MS

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; 4 AMINOBUTYRIC ACID; 5 HYDROXYINDOLEACETIC ACID; ACETONITRILE; FORMIC ACID; HOMOVANILLIC ACID; MONOAMINE; SCHISANDRA CHINENSIS EXTRACT; SEROTONIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN HOMOGENATE; CONTROLLED STUDY; DRUG DETERMINATION; INSOMNIA; LIMIT OF QUANTITATION; MALE; METABOLITE; NONHUMAN; PRIORITY JOURNAL; RAT; SCHISANDRA CHINENSIS; SEDATION; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

BRAIN SAMPLES; NEUROTRANSMITTERS; SCHISANDRA CHINENSIS (TURCZ.); SEDATIVE AND HYPNOTIC; UFLC-MS/MS;

AMINES; AMINO ACIDS; ANIMALS; BRAIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYPNOTICS AND SEDATIVES; MALE; MEDICINE, CHINESE TRADITIONAL; NEUROTRANSMITTER AGENTS; QUALITY CONTROL; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SCHISANDRA; TANDEM MASS SPECTROMETRY;

EID: 84886256258     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2013.09.022     Document Type: Article

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