Twist1 Promotes Gastric Cancer Cell Proliferation through Up-Regulation of FoxM1

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Qian, Jianxin ^a   Luo, Yizhou ^b   Gu, Xiaoqiang ^a   Zhan, Wang ^a   Wang, Xi ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b The 454th Hospital of PLA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

FORKHEAD BOX PROTEIN M1; FORKHEAD TRANSCRIPTION FACTOR; MESSENGER RNA; TRANSCRIPTION FACTOR TWIST; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME BINDING; ENZYME INDUCTION; ENZYME MECHANISM; FOXM1 GENE; GENE; GENE EXPRESSION; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; PROMOTER REGION; PROTEIN EXPRESSION; RNA TRANSCRIPTION; STOMACH CANCER; TWIST 1 GENE;

CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; NUCLEAR PROTEINS; PROMOTER REGIONS, GENETIC; STOMACH NEOPLASMS; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; TWIST TRANSCRIPTION FACTOR; UP-REGULATION;

EID: 84886248231     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0077625     Document Type: Article

References (33)

1. Christiansen JJ, Rajasekaran AK, (2006) Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis. Cancer Res 66: 8319-8326. doi:10.1158/0008-5472.CAN-06-0410. PubMed: 16951136.
2. De Craene B, Berx G, (2013) Regulatory networks defining EMT during cancer initiation and progression.Nat Rev Cancer 13: 97-110. doi:10.1038/nrc3447. PubMed: 23344542.
3. Tsuji T, Ibaragi S, Hu GF, (2009) Epithelial-mesenchymal transition and cell cooperativity in metastasis. Cancer Res 69: 7135-7139. doi:10.1158/0008-5472.CAN-09-1618. PubMed: 19738043.
4. Yang J, Mani SA, Weinberg RA, (2006) Exploring a new twist on tumor metastasis. Cancer Res 66: 4549-4552. doi:10.1158/0008-5472.CAN-05-3850. PubMed: 16651402.
5. Nieto MA, (2002) The snail superfamily of zinc-finger transcription factors. Nat Rev Mol Cell Biol 3: 155-166. doi:10.1038/nrm757. PubMed: 11994736.
6. Cheng GZ, Zhang W, Wang LH, (2008) Regulation of cancer cell survival, migration, and invasion by Twist: AKT2 comes to interplay. Cancer Res 68: 957-960. doi:10.1158/0008-5472.CAN-07-5067. PubMed: 18281467.
7. VanDusen NJ, Firulli AB, (2012) Twist factor regulation of non-cardiomyocyte cell lineages in the developing heart. Differentiation 84: 79-88. doi:10.1016/j.diff.2012.03.002. PubMed: 22516205.
8. Qin Q, Xu Y, He T, Qin C, Xu J, (2012) Normal and disease-related biological functions of Twist1 and underlying molecular mechanisms. Cell Res 22: 90-106. doi:10.1038/cr.2011.144. PubMed: 21876555.
9. Yang J, Mani SA, Donaher JL, Ramaswamy S, Itzykson RA, et al. (2004) Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 117: 927-939. doi:10.1016/j.cell.2004.06.006. PubMed: 15210113.
10. Horikawa T, Yang J, Kondo S, Yoshizaki T, Joab I, et al. (2007) Twist and epithelial-mesenchymal transition are induced by the EBV oncoprotein latent membrane protein 1 and are associated with metastatic nasopharyngeal carcinoma. Cancer Res 67: 1970-1978. doi:10.1158/0008-5472.CAN-06-3933. PubMed: 17332324.
11. Kang Y, Massagué J, (2004) Epithelial-mesenchymal transitions: twist in development and metastasis. Cell 118: 277-279. doi:10.1016/j.cell.2004.07.011. PubMed: 15294153.
12. Stasinopoulos IA, Mironchik Y, Raman A, Wildes F, Winnard P Jr, et al. (2005) HOXA5-twist interaction alters p53 homeostasis in breast cancer cells. J Biol Chem 280: 2294-2299. PubMed: 15545268.
13. Michel L, Jean-Louis F, Begue E, Bensussan A, Bagot M, (2013) Use of PLS3, Twist, CD158k/KIR3DL2, and NKp46 gene expression combination for reliable Sézary syndrome diagnosis. Blood 121: 1477-1478. doi:10.1182/blood-2012-10-460535. PubMed: 23429988.
14. Xue Z, Yan H, Li J, Liang S, Cai X, et al. (2012) Identification of cancer stem cells in vincristine preconditioned SGC7901 gastric cancer cell line. J Cell Biochem 113: 302-312. doi:10.1002/jcb.23356. PubMed: 21913215.
15. Sung CO, Lee KW, Han S, Kim SH, (2011) Twist1 is up-regulated in gastric cancer-associated fibroblasts with poor clinical outcomes. Am J Pathol 179: 1827-1838. doi:10.1016/j.ajpath.2011.06.032. PubMed: 21854747.
16. Luo GQ, Li JH, Cao L, Zhou YH, Wen JF, (2011) Activator protein-1 involvement in proliferation inhibition by gene silencing of Twist in gastric cancer cells. Pathology 4: 697-701. PubMed: 22002117.
17. Qin Q, Xu Y, He T, Qin C, Xu J, (2012) Normal and disease-related biological functions of Twist1 and underlying molecular mechanisms. Cell Res 22: 90-106. doi:10.1038/cr.2011.144. PubMed: 21876555.
18. Pan D, Fujimoto M, Lopes A, Wang YX, (2009) Twist-1 is a PPARdelta-inducible, negative-feedback regulator of PGC-1alpha in brown fat metabolism. Cell 137: 73-86. doi:10.1016/j.cell.2009.01.051. PubMed: 19345188.
19. Gort EH, Suijkerbuijk KP, Roothaan SM, Raman V, Vooijs M, et al. (2008) Methylation of the TWIST1 promoter, TWIST1 mRNA levels, and immunohistochemical expression of TWIST1 in breast cancer. Cancer Epidemiol Biomarkers Prev 17: 3325-3330. doi:10.1158/1055-9965.EPI-08-0472. PubMed: 19064546.
20. Rosivatz E, Becker I, Specht K, Fricke E, Luber B, et al. (2002) Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancer. Am J Pathol 161: 1881-1891.
21. Wonsey DR, Follettie MT, (2005) Loss of the forkhead transcription factor FoxM1 causes centrosome amplification and mitotic catastrophe. Cancer Res 65: 5181-5189. doi:10.1158/0008-5472.CAN-04-4059. PubMed: 15958562.
22. Kim IM, Ackerson T, Ramakrishna S, Tretiakova M, Wang IC, et al. (2006) The Forkhead Box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer. Cancer Res 66: 2153-2161. doi:10.1158/0008-5472.CAN-05-3003. PubMed: 16489016.
23. Radhakrishnan SK, Bhat UG, Hughes DE, Wang IC, Costa RH, et al. (2006) Identification of a chemical inhibitor of the oncogenic transcription factor forkhead box M1. Cancer Res 66: 9731-9735. doi:10.1158/0008-5472.CAN-06-1576. PubMed: 17018632.
24. Kong X, Li L, Li Z, Le X, Huang C, et al. (2013) Dysregulated expression of FOXM1 isoforms drive progression of pancreatic cancer. Cancer Res.
25. Horimoto Y, Hartman J, Millour J, Pollock S, Olmos Y, et al. (2011) ERβ1 represses FOXM1 expression through targeting ERα to control cell proliferation in breast cancer. Am J Pathol 179: 1148-1156. doi:10.1016/j.ajpath.2011.05.052. PubMed: 21763263.
26. Karadedou CT, Gomes AR, Chen J, Petkovic M, Ho KK, et al. (2012) FOXO3a represses VEGF expression through FOXM1-dependent and-independent mechanisms in breast cancer. Oncogene 31: 1845-1858. doi:10.1038/onc.2011.368. PubMed: 21860419.
27. Xia L, Mo P, Huang W, Zhang L, Wang Y, et al. (2012) The TNF-α/ROS/HIF-1-induced upregulation of FoxMI expression promotes HCC proliferation and resistance to apoptosis. Carcinogenesis 33: 2250-2259. doi:10.1093/carcin/bgs249. PubMed: 22831955.
28. Zeng J, Wang L, Li Q, Li W, Björkholm M, et al. (2009) FoxM1 is up-regulated in gastric cancer and its inhibition leads to cellular senescence, partially dependent on p27 kip1. J Pathol 218: 419-427. doi:10.1002/path.2530. PubMed: 19235838.
29. Feng Y, Wang L, Zeng J, Shen L, Liang X, et al. (2013) Fork head box M1 is overexpressed in Helicobacter pylori-induced gastric carcinogenesis and is negatively regulated by hsa-miR-370. Mol Cancer Res.
30. Gong A, Huang S, (2012) FoxM1 and Wnt/β-catenin signaling in glioma stem cells. Cancer Res 72: 5658-5662. doi:10.1158/1538-7445.AM2012-5658. PubMed: 23139209.
31. Li Q, Zhang N, Jia Z, Le X, Dai B, et al. (2009) Critical role and regulation of transcription factor FoxM1 in human gastric cancer angiogenesis and progression. Cancer Res 69: 3501-3509. doi:10.1158/0008-5472.CAN-08-3045. PubMed: 19351851.
32. Sullivan C, Liu Y, Shen J, Curtis A, Newman C, et al. (2012) Novel interactions between FOXM1 and CDC25A regulate the cell cycle. PLOS ONE 7: e51277. doi:10.1371/journal.pone.0051277. PubMed: 23240008.
33. Li J, Wang Y, Luo J, Fu Z, Ying J, et al. (2012) miR-134 inhibits epithelial to mesenchymal transition by targeting FOXM1 in non-small cell lung cancer cells. FEBS Lett 586: 3761-3765. doi:10.1016/j.febslet.2012.09.016. PubMed: 23010597.