Lysine-specific demethylase 2A (KDM2A) normalizes human embryonic stem cell derived keratinocytes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 24, 2012, Pages 9442-9447

  Iuchi, Shiro ^a   Green, Howard ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Development; Differentiation; Epigenetics; Expression vector; Transcript isomers

Indexed keywords

COMPLEMENTARY DNA; F BOX PROTEIN; LYSINE SPECIFIC DEMETHYLASE 2A; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYONIC STEM CELL; ENZYME ACTIVITY; EPIGENETICS; EXPRESSION VECTOR; GENE EXPRESSION; GENETIC CODE; HUMAN; HUMAN CELL; ISOMER; KERATINOCYTE; LIFESPAN; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN;

3T3 CELLS; ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; COCULTURE TECHNIQUES; EMBRYONIC STEM CELLS; F-BOX PROTEINS; GENETIC VECTORS; HUMANS; KERATINOCYTES; MICE; MOLECULAR SEQUENCE DATA; OXIDOREDUCTASES, N-DEMETHYLATING; POLYMERASE CHAIN REACTION; RETROVIRIDAE; RNA, MESSENGER;

EID: 84862214531     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1206176109     Document Type: Article

References (19)

1. Green H, Easley K, Iuchi S (2003) Marker succession during the development of keratinocytes from cultured human embryonic stem cells. Proc Natl Acad Sci USA 100: 15625-15630. (Pubitemid 38021040)
2. Iuchi S, Dabelsteen S, Easley K, Rheinwald JG, Green H (2006) Immortalized keratinocyte lines derived from human embryonic stem cells. Proc Natl Acad Sci USA 103: 1792-1797. (Pubitemid 43228772)
3. Kipreos ET, Pagano M (2000) The F-box protein family. Genome Biol 1(5). REVIEWS 3002.
4. Tsukada Y, et al. (2006) Histone demethylation by a family of JmjC domain-containing proteins. Nature 439:811-816. (Pubitemid 43255695)
5. Lu T, et al. (2009) Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFkappaB. Proc Natl Acad Sci USA 106: 16339-16344.
6. Lu T, et al. (2010) Regulation of NF-kappaB by NSD1/FBXL11-dependent reversible lysine methylation of p65. Proc Natl Acad Sci USA 107:46-51.
7. Hannon GJ, et al. (1999) MaRX: An approach to genetics in mammalian cells. Science 283:1129-1130.
8. Gil J, Bernard D, Martínez D, Beach D (2004) Polycomb CBX7 has a unifying role in cellular lifespan. Nat Cell Biol 6:67-72. (Pubitemid 38425732)
9. Van Melderen L (2002) Molecular interactions of the CcdB poison with its bacterial target, the DNA gyrase. Int J Med Microbiol 291:537-544.
10. Ory DS, Neugeboren BA, Mulligan RC (1996) A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes. Proc Natl Acad Sci USA 93:11400-11406. (Pubitemid 26347133)
11. Shepard AR, Rae JL (1997) Magnetic bead capture of cDNAs from double-stranded plasmid cDNA libraries. Nucleic Acids Res 25:3183-3185. (Pubitemid 27331417)
12. Kozak M (1989) The scanning model for translation: An update. J Cell Biol 108: 229-241.
13. Blackledge NP, et al. (2010) CpG islands recruit a histone H3 lysine 36 demethylase. Mol Cell 38:179-190.
14. Klose RJ, Kallin EM, Zhang Y (2006) JmjC-domain-containing proteins and histone demethylation. Nat Rev Genet 7:715-727. (Pubitemid 44260007)
15. Wang Y, Ng TY (2006) Phosphatase 2A negatively regulates mitotic exit in Saccharomyces cerevisiae. Mol Biol Cell 17:80-89. (Pubitemid 43049463)
16. Bartke T, et al. (2010) Nucleosome-interacting proteins regulated by DNA and histone methylation. Cell 143:470-484.
17. Tanaka Y, et al. (2010) JmjC enzyme KDM2A is a regulator of rRNA transcription in response to starvation. EMBO J 29:1510-1522.
18. Allen-Hoffmann BL, Rheinwald JG (1984) Polycyclic aromatic hydrocarbon mutagenesis of human epidermal keratinocytes in culture. Proc Natl Acad Sci USA 81: 7802-7806. (Pubitemid 15169149)
19. Simon M, Green H (1985) Enzymatic cross-linking of involucrin and other proteins by keratinocyte particulates in vitro. Cell 40:677-683. (Pubitemid 15076583)