-
1
-
-
42549117180
-
Pharmaceutical and pharmacological importance of peptide transporters
-
18416933 10.1211/jpp.60.5.0002 1:CAS:528:DC%2BD1cXltlemtr4%3D
-
Brandsch M, Knutter I, Bosse-Doenecke E. Pharmaceutical and pharmacological importance of peptide transporters. J Pharm Pharmacol. 2008;60:543-85.
-
(2008)
J Pharm Pharmacol
, vol.60
, pp. 543-585
-
-
Brandsch, M.1
Knutter, I.2
Bosse-Doenecke, E.3
-
2
-
-
48749131090
-
Peptide transporters and their roles in physiological processes and drug disposition
-
18668438 10.1080/00498250701875254 1:CAS:528:DC%2BD1cXpt1SntLc%3D
-
Rubio-Aliaga I, Daniel H. Peptide transporters and their roles in physiological processes and drug disposition. Xenobiotica. 2008;38:1022-42.
-
(2008)
Xenobiotica
, vol.38
, pp. 1022-1042
-
-
Rubio-Aliaga, I.1
Daniel, H.2
-
3
-
-
84873329542
-
Proton-coupled oligopeptide transporter family SLC15: Physiological, pharmacological and pathological implications
-
23506874 10.1016/j.mam.2012.11.003 1:CAS:528:DC%2BC3sXksVyrurs%3D
-
Smith DE, Clemençon B, Hediger MA. Proton-coupled oligopeptide transporter family SLC15: physiological, pharmacological and pathological implications. Mol Aspects Med. 2013;34:323-36.
-
(2013)
Mol Aspects Med
, vol.34
, pp. 323-336
-
-
Smith, D.E.1
Clemençon, B.2
Hediger, M.A.3
-
4
-
-
0030892082
-
Cloning and functional expression of a brain peptide/histidine transporter
-
9092568 10.1074/jbc.272.17.11408 1:CAS:528:DyaK2sXisFOmtbw%3D
-
Yamashita T, Shimada S, Guo W, Sato K, Kohmura E, Hayakawa T, et al. Cloning and functional expression of a brain peptide/histidine transporter. J Biol Chem. 1997;272:10205-11.
-
(1997)
J Biol Chem
, vol.272
, pp. 10205-10211
-
-
Yamashita, T.1
Shimada, S.2
Guo, W.3
Sato, K.4
Kohmura, E.5
Hayakawa, T.6
-
5
-
-
0035874469
-
Cloning of a lymphatic peptide/histidine transporter
-
11336635 10.1042/0264-6021:3560053 1:CAS:528:DC%2BD3MXjvF2itrY%3D
-
Sakata K, Yamashita T, Maeda M, Moriyama Y, Shimada S, Tohyama M. Cloning of a lymphatic peptide/histidine transporter. Biochem J. 2001;356(Pt 1):53-60.
-
(2001)
Biochem J
, vol.356
, Issue.PART 1
, pp. 53-60
-
-
Sakata, K.1
Yamashita, T.2
Maeda, M.3
Moriyama, Y.4
Shimada, S.5
Tohyama, M.6
-
6
-
-
0031662109
-
5′-Amino acid esters of antiviral nucleosides, acyclovir, and AZT are absorbed by the intestinal PEPT1 peptide transporter
-
9706043 10.1023/A:1011919319810 1:CAS:528:DyaK1cXltFynsb4%3D
-
Han H, de Vrueh RL, Rhie JK, Covitz KM, Smith PL, Lee CP, et al. 5′-Amino acid esters of antiviral nucleosides, acyclovir, and AZT are absorbed by the intestinal PEPT1 peptide transporter. Pharm Res. 1998;15:1154-9.
-
(1998)
Pharm Res
, vol.15
, pp. 1154-1159
-
-
Han, H.1
De Vrueh, R.L.2
Rhie, J.K.3
Covitz, K.M.4
Smith, P.L.5
Lee, C.P.6
-
7
-
-
0040699988
-
Intestinal transport of beta-lactam antibiotics: Analysis of the affinity at the H+/peptide symporter (PEPT1), the uptake into Caco-2 cell monolayers and the transepithelial flux
-
9950279 10.1023/A:1018814627484 1:CAS:528:DyaK1MXmtlGmsQ%3D%3D
-
Bretschneider B, Brandsch M, Neubert R. Intestinal transport of beta-lactam antibiotics: analysis of the affinity at the H+/peptide symporter (PEPT1), the uptake into Caco-2 cell monolayers and the transepithelial flux. Pharm Res. 1999;16:55-61.
-
(1999)
Pharm Res
, vol.16
, pp. 55-61
-
-
Bretschneider, B.1
Brandsch, M.2
Neubert, R.3
-
8
-
-
0036710840
-
Mammalian peptide transporters as targets for drug delivery
-
12237156 10.1016/S0165-6147(02)02072-2 1:CAS:528:DC%2BD38XntVWmtr4%3D
-
Rubio-Aliaga I, Daniel H. Mammalian peptide transporters as targets for drug delivery. Trends Pharmacol Sci. 2002;23:434-40.
-
(2002)
Trends Pharmacol Sci
, vol.23
, pp. 434-440
-
-
Rubio-Aliaga, I.1
Daniel, H.2
-
9
-
-
0017327815
-
Cefadroxil, a new broad-spectrum cephalosporin
-
848939 10.1128/AAC.11.2.324 1:CAS:528:DyaE2sXhvVeisrY%3D
-
Buck RE, Price KE. Cefadroxil, a new broad-spectrum cephalosporin. Antimicrob Agents Chemother. 1977;11:324-30.
-
(1977)
Antimicrob Agents Chemother
, vol.11
, pp. 324-330
-
-
Buck, R.E.1
Price, K.E.2
-
10
-
-
0022980304
-
Cefadroxil: A review of its antibacterial, pharmacokinetic and therapeutic properties in comparison with cephalexin and cephradine
-
3542485 10.2165/00003495-198600323-00003 1:CAS:528:DyaL2sXnvVSmsA%3D%3D
-
Tanrisever B, Santella PJ. Cefadroxil: a review of its antibacterial, pharmacokinetic and therapeutic properties in comparison with cephalexin and cephradine. Drugs. 1986;32 Suppl 3:1-16.
-
(1986)
Drugs
, vol.32
, Issue.SUPPL. 3
, pp. 1-16
-
-
Tanrisever, B.1
Santella, P.J.2
-
11
-
-
0020029853
-
Influence of dosage form and administration route on the pharmacokinetic parameters of cefadroxil
-
7061182 1:STN:280:DyaL387ktFahug%3D%3D
-
Marino EL, Dominguez-Gil A, Muriel C. Influence of dosage form and administration route on the pharmacokinetic parameters of cefadroxil. Int J Clin Pharmacol Ther Toxicol. 1982;20:73-7.
-
(1982)
Int J Clin Pharmacol Ther Toxicol
, vol.20
, pp. 73-77
-
-
Marino, E.L.1
Dominguez-Gil, A.2
Muriel, C.3
-
12
-
-
0019794587
-
Intestinal absorption mechanism of amphoteric beta-lactam antibiotics I: Comparative absorption and evidence for saturable transport of amino-beta-lactam antibiotics by in situ rat small intestine
-
7264924 10.1002/jps.2600700714 1:CAS:528:DyaL3MXksFCls7c%3D
-
Tsuji A, Nakashima E, Kagami I, Yamana T. Intestinal absorption mechanism of amphoteric beta-lactam antibiotics I: comparative absorption and evidence for saturable transport of amino-beta-lactam antibiotics by in situ rat small intestine. J Pharm Sci. 1981;70:768-72.
-
(1981)
J Pharm Sci
, vol.70
, pp. 768-772
-
-
Tsuji, A.1
Nakashima, E.2
Kagami, I.3
Yamana, T.4
-
13
-
-
84857382438
-
Oral availability of cefadroxil depends on ABCC3 and ABCC4
-
22166395 10.1124/dmd.111.041731
-
de Waart DR, van de Wetering K, Kunne C, Duijst S, Paulusma CC, Oude Elferink RP. Oral availability of cefadroxil depends on ABCC3 and ABCC4. Drug Metab Dispos. 2012;40:515-21.
-
(2012)
Drug Metab Dispos
, vol.40
, pp. 515-521
-
-
De Waart, D.R.1
Van De Wetering, K.2
Kunne, C.3
Duijst, S.4
Paulusma, C.C.5
Oude Elferink, R.P.6
-
14
-
-
0032967296
-
Localization of PEPT1 and PEPT2 proton-coupled oligopeptide transporter mRNA and protein in rat kidney
-
10330047 1:CAS:528:DyaK1MXjsVWlsr4%3D
-
Shen H, Smith DE, Yang T, Huang YG, Schnermann JB, Brosius 3rd FC. Localization of PEPT1 and PEPT2 proton-coupled oligopeptide transporter mRNA and protein in rat kidney. Am J Physiol. 1999;276:F658-65.
-
(1999)
Am J Physiol
, vol.276
-
-
Shen, H.1
Smith, D.E.2
Yang, T.3
Huang, Y.G.4
Schnermann, J.B.5
Brosius III, F.C.6
-
15
-
-
4644239463
-
Immunolocalization of the proton-coupled oligopeptide transporter PEPT2 in developing rat brain
-
15981584 10.1021/mp049944b 1:CAS:528:DC%2BD2cXkslWitb4%3D
-
Shen H, Smith DE, Keep RF, Brosius 3rd FC. Immunolocalization of the proton-coupled oligopeptide transporter PEPT2 in developing rat brain. Mol Pharm. 2004;1:248-56.
-
(2004)
Mol Pharm
, vol.1
, pp. 248-256
-
-
Shen, H.1
Smith, D.E.2
Keep, R.F.3
Brosius III, F.C.4
-
16
-
-
0036171510
-
Tissue distribution and induction of human multidrug resistant protein 3
-
11850532 10.1038/labinvest.3780411 1:CAS:528:DC%2BD38XitFOqtLo%3D
-
Scheffer GL, Kool M, de Haas M, de Vree JM, Pijnenborg AC, Bosman DK, et al. Tissue distribution and induction of human multidrug resistant protein 3. Lab Invest. 2002;82:193-201.
-
(2002)
Lab Invest
, vol.82
, pp. 193-201
-
-
Scheffer, G.L.1
Kool, M.2
De Haas, M.3
De Vree, J.M.4
Pijnenborg, A.C.5
Bosman, D.K.6
-
17
-
-
70449635126
-
Role of basolateral efflux transporter MRP4 in the intestinal absorption of the antiviral drug adefovir dipivoxil
-
19735648 10.1016/j.bcp.2009.08.029 1:CAS:528:DC%2BD1MXhsVKntb7P
-
Ming X, Thakker DR. Role of basolateral efflux transporter MRP4 in the intestinal absorption of the antiviral drug adefovir dipivoxil. Biochem Pharmacol. 2010;79:455-62.
-
(2010)
Biochem Pharmacol
, vol.79
, pp. 455-462
-
-
Ming, X.1
Thakker, D.R.2
-
18
-
-
41349107158
-
Multidrug resistance protein 4 (MRP4/ABCC4): A versatile efflux transporter for drugs and signaling molecules
-
18353444 10.1016/j.tips.2008.01.006 1:CAS:528:DC%2BD1cXksVehsrs%3D
-
Russel FG, Koenderink JB, Masereeuw R. Multidrug resistance protein 4 (MRP4/ABCC4): a versatile efflux transporter for drugs and signaling molecules. Trends Pharmacol Sci. 2008;29:200-7.
-
(2008)
Trends Pharmacol Sci
, vol.29
, pp. 200-207
-
-
Russel, F.G.1
Koenderink, J.B.2
Masereeuw, R.3
-
19
-
-
77649216536
-
Membrane transporters in drug development
-
International Transporter Consortium 20190787 10.1038/nrd3028 1:CAS:528:DC%2BC3cXisFelu74%3D
-
International Transporter Consortium, Giacomini KM, Huang SM, Tweedie DJ, Benet LZ, Brouwer KL, et al. Membrane transporters in drug development. Nat Rev Drug Discov. 2010;9:215-36.
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 215-236
-
-
Giacomini, K.M.1
Huang, S.M.2
Tweedie, D.J.3
Benet, L.Z.4
Brouwer, K.L.5
-
20
-
-
0024598879
-
Non-linear intestinal absorption kinetics of cefadroxil in the rat
-
2568445 10.1111/j.2042-7158.1989.tb06425.x
-
Sánchez-Picó A, Peris-Ribera JE, Toledano C, Torres-Molina F, Casabó VG, Martín-Villodre A, et al. Non-linear intestinal absorption kinetics of cefadroxil in the rat. J Pharm Pharmacol. 1989;41:179-85.
-
(1989)
J Pharm Pharmacol
, vol.41
, pp. 179-185
-
-
Sánchez-Picó, A.1
Peris-Ribera, J.E.2
Toledano, C.3
Torres-Molina, F.4
Casabó, V.G.5
Martín-Villodre, A.6
-
21
-
-
0025868537
-
Dose-dependent absorption and elimination of cefadroxil in man
-
1743250 10.1007/BF00265914 1:STN:280:DyaK38%2FnslSrtA%3D%3D
-
Garrigues TM, Martin U, Peris-Ribera JE, Prescott LF. Dose-dependent absorption and elimination of cefadroxil in man. Eur J Clin Pharmacol. 1991;41:179-83.
-
(1991)
Eur J Clin Pharmacol
, vol.41
, pp. 179-183
-
-
Garrigues, T.M.1
Martin, U.2
Peris-Ribera, J.E.3
Prescott, L.F.4
-
22
-
-
34250738921
-
Impact of genetic knockout of PEPT2 on cefadroxil pharmacokinetics, renal tubular reabsorption, and brain penetration in mice
-
17452417 10.1124/dmd.107.015263
-
Shen H, Ocheltree SM, Hu Y, Keep RF, Smith DE. Impact of genetic knockout of PEPT2 on cefadroxil pharmacokinetics, renal tubular reabsorption, and brain penetration in mice. Drug Metab Dispos. 2007;35:1209-16.
-
(2007)
Drug Metab Dispos
, vol.35
, pp. 1209-1216
-
-
Shen, H.1
Ocheltree, S.M.2
Hu, Y.3
Keep, R.F.4
Smith, D.E.5
-
23
-
-
84876481462
-
Relevance of PepT1 in the intestinal permeability and oral absorption of cefadroxil
-
23224978 10.1007/s11095-012-0937-8 1:CAS:528:DC%2BC38Xhslyksb%2FM
-
Posada MM, Smith DE. Relevance of PepT1 in the intestinal permeability and oral absorption of cefadroxil. Pharm Res. 2013;30:1017-25.
-
(2013)
Pharm Res
, vol.30
, pp. 1017-1025
-
-
Posada, M.M.1
Smith, D.E.2
-
24
-
-
64649096522
-
Targeted disruption of peptide transporter Pept1 gene in mice significantly reduces dipeptide absorption in intestine
-
19434858 10.1021/mp8001655 1:CAS:528:DC%2BD1cXhtlemt73J
-
Hu Y, Smith DE, Ma K, Jappar D, Thomas W, Hillgren KM. Targeted disruption of peptide transporter Pept1 gene in mice significantly reduces dipeptide absorption in intestine. Mol Pharm. 2008;5:1122-30.
-
(2008)
Mol Pharm
, vol.5
, pp. 1122-1130
-
-
Hu, Y.1
Smith, D.E.2
Ma, K.3
Jappar, D.4
Thomas, W.5
Hillgren, K.M.6
-
26
-
-
77957164933
-
Significance and regional dependency of peptide transporter (PEPT) 1 in the intestinal permeability of glycylsarcosine: In situ single-pass perfusion studies in wild-type and Pept1 knockout mice
-
20660104 10.1124/dmd.110.034025 1:CAS:528:DC%2BC3cXht1eisLjF
-
Jappar D, Wu SP, Hu Y, Smith DE. Significance and regional dependency of peptide transporter (PEPT) 1 in the intestinal permeability of glycylsarcosine: in situ single-pass perfusion studies in wild-type and Pept1 knockout mice. Drug Metab Dispos. 2010;38:1740-6.
-
(2010)
Drug Metab Dispos
, vol.38
, pp. 1740-1746
-
-
Jappar, D.1
Wu, S.P.2
Hu, Y.3
Smith, D.E.4
-
27
-
-
81855173578
-
Effect of dose escalation on the in vivo oral absorption and disposition of glycylsarcosine in wild-type and Pept1 knockout mice
-
21880829 10.1124/dmd.111.041087 1:CAS:528:DC%2BC3MXhsFCrurfP
-
Jappar D, Hu Y, Smith DE. Effect of dose escalation on the in vivo oral absorption and disposition of glycylsarcosine in wild-type and Pept1 knockout mice. Drug Metab Dispos. 2011;39:2250-7.
-
(2011)
Drug Metab Dispos
, vol.39
, pp. 2250-2257
-
-
Jappar, D.1
Hu, Y.2
Smith, D.E.3
-
28
-
-
0020036496
-
Pharmacokinetics of cefadroxil after oral administration in humans
-
7073267 10.1128/AAC.21.2.320
-
La Rosa F, Ripa S, Prenna M, Ghezzi A, Pfeffer M. Pharmacokinetics of cefadroxil after oral administration in humans. Antimicrob Agents Chemother. 1982;21:320-2.
-
(1982)
Antimicrob Agents Chemother
, vol.21
, pp. 320-322
-
-
La Rosa, F.1
Ripa, S.2
Prenna, M.3
Ghezzi, A.4
Pfeffer, M.5
-
29
-
-
37849031379
-
Measurements of rat and mouse gastrointestinal pH, fluid and lymphoid tissue, and implications for in-vivo experiments
-
18088506 10.1211/jpp.60.1.0008 1:CAS:528:DC%2BD1cXhsV2ksbY%3D
-
McConnell EL, Basit AW, Murdan S. Measurements of rat and mouse gastrointestinal pH, fluid and lymphoid tissue, and implications for in-vivo experiments. J Pharm Pharmacol. 2008;60:63-70.
-
(2008)
J Pharm Pharmacol
, vol.60
, pp. 63-70
-
-
McConnell, E.L.1
Basit, A.W.2
Murdan, S.3
-
30
-
-
84874045942
-
Significance of peptide transporter 1 in the intestinal permeability of valacyclovir in wild-type and PepT1 knockout mice
-
23264448 10.1124/dmd.112.049239 1:CAS:528:DC%2BC3sXivVyqs7Y%3D
-
Yang B, Smith DE. Significance of peptide transporter 1 in the intestinal permeability of valacyclovir in wild-type and PepT1 knockout mice. Drug Metab Dispos. 2013;41:608-14.
-
(2013)
Drug Metab Dispos
, vol.41
, pp. 608-614
-
-
Yang, B.1
Smith, D.E.2
-
31
-
-
84860864847
-
Influence of fed-fasted state on intestinal PEPT1 expression and in vivo pharmacokinetics of glycylsarcosine in wild-type and Pept1 knockout mice
-
21904935 10.1007/s11095-011-0580-9 1:CAS:528:DC%2BC3MXhtFersLfO
-
Ma K, Hu Y, Smith DE. Influence of fed-fasted state on intestinal PEPT1 expression and in vivo pharmacokinetics of glycylsarcosine in wild-type and Pept1 knockout mice. Pharm Res. 2012;29:535-45.
-
(2012)
Pharm Res
, vol.29
, pp. 535-545
-
-
Ma, K.1
Hu, Y.2
Smith, D.E.3
-
32
-
-
0027466872
-
Nonlinear pharmacokinetics of cefadroxil in the rat
-
8097688
-
García-Carbonell MC, Granero L, Torres-Molina F, Aristorena JC, Chesa-Jiménez J, Plá-Delfina JM, et al. Nonlinear pharmacokinetics of cefadroxil in the rat. Drug Metab Dispos. 1993;21:215-7.
-
(1993)
Drug Metab Dispos
, vol.21
, pp. 215-217
-
-
García-Carbonell, M.C.1
Granero, L.2
Torres-Molina, F.3
Aristorena, J.C.4
Chesa-Jiménez, J.5
Plá-Delfina, J.M.6
-
33
-
-
0019137130
-
Influence of dose on the pharmacokinetics of cefadroxil
-
7461017 10.1007/BF00874664
-
Mariño EL, Dominguez-Gil A. Influence of dose on the pharmacokinetics of cefadroxil. Eur J Clin Pharmacol. 1980;18:505-9.
-
(1980)
Eur J Clin Pharmacol
, vol.18
, pp. 505-509
-
-
Mariño, E.L.1
Dominguez-Gil, A.2
-
34
-
-
0029947071
-
A pharmacokinetic comparison of cefadroxil and cephalexin after administration of 250, 500 and 1000 mg solution doses
-
8743403 10.1002/(SICI)1099-081X(199605)17:4<319: AID-BDD957>3.0. CO;2-W 1:CAS:528:DyaK28Xjt1Ggu7k%3D
-
Barbhaiya RH. A pharmacokinetic comparison of cefadroxil and cephalexin after administration of 250, 500 and 1000 mg solution doses. Biopharm Drug Dispos. 1996;17:319-30.
-
(1996)
Biopharm Drug Dispos
, vol.17
, pp. 319-330
-
-
Barbhaiya, R.H.1
-
35
-
-
25644448895
-
Role and relevance of peptide transporter 2 (PEPT2) in the kidney and choroid plexus: In vivo studies with glycylsarcosine in wild-type and PEPT2 knockout mice
-
15987832 10.1124/jpet.105.089359 1:CAS:528:DC%2BD2MXhtVOks73J
-
Ocheltree SM, Shen H, Hu Y, Keep RF, Smith DE. Role and relevance of peptide transporter 2 (PEPT2) in the kidney and choroid plexus: in vivo studies with glycylsarcosine in wild-type and PEPT2 knockout mice. J Pharmacol Exp Ther. 2005;315:240-7.
-
(2005)
J Pharmacol Exp Ther
, vol.315
, pp. 240-247
-
-
Ocheltree, S.M.1
Shen, H.2
Hu, Y.3
Keep, R.F.4
Smith, D.E.5
|