Influence of fed-fasted state on intestinal PEPT1 expression and in vivo pharmacokinetics of glycylsarcosine in wild-type and Pept1 knockout mice

Pharmaceutical Research

Volumn 29, Issue 2, 2012, Pages 535-545

  Ma, Ke ^a   Hu, Yongjun ^a   Smith, David E ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Fed fasted state; Glycylsarcosine; Intestinal PEPT1; Knockout mice; Oral absorption

Indexed keywords

GLYCYLSARCOSINE; PEPTIDE TRANSPORTER 1; COTRANSPORTER; DIPEPTIDE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIET RESTRICTION; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG MECHANISM; FEMALE; IMMUNOBLOTTING; IN VIVO STUDY; KNOCKOUT MOUSE; MALE; MAXIMUM PLASMA CONCENTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SMALL INTESTINE; TISSUE DISTRIBUTION; WILD TYPE; ANIMAL; C57BL MOUSE; GENE EXPRESSION REGULATION; GENETICS; INTESTINE; METABOLISM; MOUSE MUTANT; ULTRASTRUCTURE;

ANIMALS; DIPEPTIDES; FASTING; FEMALE; GENE EXPRESSION REGULATION; INTESTINES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; SYMPORTERS;

EID: 84860864847     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-011-0580-9     Document Type: Article

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