Antihypertensive and vasorelaxant effects of dihydrospinochalcone-A isolated from Lonchocarpus xuul Lundell by NO production: Computational and ex vivo approaches

Phytomedicine

Volumn 20, Issue 14, 2013, Pages 1241-1246

  Avila Villarreal, Gabriela ^a   Hernández Abreu, Oswaldo ^a   Hidalgo Figueroa, Sergio ^a   Navarrete Vázquez, Gabriel ^a   Escalante Erosa, Fabiola ^b   Peña Rodríguez, Luis M ^b   Villalobos Molina, Rafael ^c   Estrada Soto, Samuel ^a  

^a UNIVERSIDAD AUTÓNOMA DEL ESTADO DE MORELOS   (Mexico)

^b CENTRO DE INVESTIGACIÓN CIENTÍFICA DE YUCATÁN   (Mexico)

^c UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Antihypertensive; Dihydrospinochalcone A; Docking; Isocordoin; Lonchocarpus xuul; Nitric oxide; Vasorelaxant

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; ANTIHYPERTENSIVE AGENT; ATROPINE; CARBACHOL; CHALCONE; DIHYDROSPINOCHALCONE A; FLAVONOID; HYDROXYL GROUP; INDOMETACIN; ISOCORDOIN; N(G) NITROARGININE METHYL ESTER; NIFEDIPINE; NITRIC OXIDE; NORADRENALIN; UNCLASSIFIED DRUG; VASODILATOR AGENT;

ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIASTOLIC BLOOD PRESSURE; ENDOTHELIUM; EX VIVO STUDY; HEART RATE; HYDROGEN BOND; LONCHOCARPUS XUUL; MEDICINAL PLANT; NONHUMAN; PRIORITY JOURNAL; RAT; SYSTOLIC BLOOD PRESSURE; VASCULAR RING; VASODILATATION;

LONCHOCARPUS XUUL; RATTUS;

ANTIHYPERTENSIVE; DIHYDROSPINOCHALCONE-A; DOCKING; ISOCORDOIN; LONCHOCARPUS XUUL; NITRIC OXIDE; VASORELAXANT;

ANIMALS; ANTIHYPERTENSIVE AGENTS; AORTA, THORACIC; ATROPINE; BLOOD PRESSURE; CATECHOLS; CHALCONES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; FABACEAE; GUANYLATE CYCLASE; HEART RATE; INDOMETHACIN; MEXICO; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; NOREPINEPHRINE; PLANT EXTRACTS; POTASSIUM CHANNEL BLOCKERS; PROTEIN BINDING; RATS; RATS, INBRED SHR; RATS, WISTAR; RECEPTORS, CYTOPLASMIC AND NUCLEAR; VASOCONSTRICTION; VASODILATOR AGENTS;

EID: 84886101005     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2013.06.011     Document Type: Article

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