Genetic variations in EGFR and ERBB4 increase susceptibility to cervical cancer

Gynecologic Oncology

Volumn 131, Issue 2, 2013, Pages 445-450

  Ma, Duanduan ^a   Hovey, Raymond L ^b   Zhang, Zhengyan ^a   Fye, Samantha ^b   Huettner, Phyllis C ^a   Borecki, Ingrid B ^a   Rader, Janet S ^b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Cervical cancer; EGFR; ERBB4; Polymorphism; Transmission disequilibrium test

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; EPIDERMAL GROWTH FACTOR RECEPTOR 4; HETERODIMER;

5' UNTRANSLATED REGION; ADULT; ALLELE; ARTICLE; CANCER SUSCEPTIBILITY; CAUCASIAN; CELL ASSAY; CONTROLLED STUDY; ENHANCER REGION; EPISTASIS; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN PAPILLOMAVIRUS TYPE 18; HUMAN PAPILLOMAVIRUS TYPE 31; HUMAN PAPILLOMAVIRUS TYPE 45; HUMAN PAPILLOMAVIRUS TYPE 52; HUMAN TISSUE; INTRON; MAJOR CLINICAL STUDY; NONHUMAN; PARENT; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REPRODUCIBILITY; SIBLING; SILENCER GENE; SINGLE NUCLEOTIDE POLYMORPHISM; UTERINE CERVIX CANCER; UTERINE CERVIX CARCINOMA; UTERINE CERVIX CARCINOMA IN SITU; UTERUS CARCINOMA;

CERVICAL CANCER; EGFR; ERBB4; POLYMORPHISM; TRANSMISSION DISEQUILIBRIUM TEST;

ADULT; CARCINOMA IN SITU; CARCINOMA, SQUAMOUS CELL; FEMALE; GENOTYPE; HUMANS; INTRONS; LINKAGE DISEQUILIBRIUM; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTOR, EPIDERMAL GROWTH FACTOR; UTERINE CERVICAL NEOPLASMS;

EID: 84886098361     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2013.07.113     Document Type: Article

References (37)

1. M. Schiffman, P.E. Castle, J. Jeronimo, A.C. Rodriguez, and S. Wacholder Human papillomavirus and cervical cancer Lancet 370 2007 890 907
2. S. Hariri, E.R. Unger, M. Sternberg, E.F. Dunne, D. Swan, and S. Patel Prevalence of genital human papillomavirus among females in the United States, the National Health and Nutrition Examination Survey, 2003-2006 J Infect Dis 204 2011 566 573
3. X. Hu, Z. Zhang, D. Ma, P.C. Huettner, L.S. Massad, and L. Nguyen TP53, MDM2, NQO1, and susceptibility to cervical cancer Cancer Epidemiol Biomarkers Prev 19 2010 755 761
4. S.S. Wang, M.C. Bratti, A.C. Rodriguez, R. Herrero, R.D. Burk, and C. Porras Common variants in immune and DNA repair genes and risk for human papillomavirus persistence and progression to cervical cancer J Infect Dis 199 2009 20 30
5. K.J. Yu, J.S. Rader, I. Borecki, Z. Zhang, and A. Hildesheim CD83 polymorphisms and cervical cancer risk Gynecol Oncol 114 2009 319 322
6. Z. Zhang, I. Borecki, L. Nguyen, D. Ma, K. Smith, and P.C. Huettner CD83 gene polymorphisms increase susceptibility to human invasive cervical cancer Cancer Res 67 2007 11202 11208
7. Y. Yarden, and M.X. Sliwkowski Untangling the ErbB signalling network Nat Rev Mol Cell Biol 2 2001 127 137
8. I. Fuchs, N. Vorsteher, H. Buhler, K. Evers, J. Sehouli, and G. Schaller The prognostic significance of human epidermal growth factor receptor correlations in squamous cell cervical carcinoma Anticancer Res 27 2007 959 963
9. A.M. Kersemaekers, G.J. Fleuren, G.G. Kenter, L.J. Van den Broek, S.M. Uljee, and J. Hermans Oncogene alterations in carcinomas of the uterine cervix: overexpression of the epidermal growth factor receptor is associated with poor prognosis Clin Cancer Res 5 1999 577 586
10. C.M. Lee, D.C. Shrieve, K.A. Zempolich, R.J. Lee, E. Hammond, and D.L. Handrahan Correlation between human epidermal growth factor receptor family (EGFR, HER2, HER3, HER4), phosphorylated Akt (P-Akt), and clinical outcomes after radiation therapy in carcinoma of the cervix Gynecol Oncol 99 2005 415 421
11. T. Maruo, M. Yamasaki, C.A. Ladines-Llave, and M. Mochizuki Immunohistochemical demonstration of elevated expression of epidermal growth factor receptor in the neoplastic changes of cervical squamous epithelium Cancer 69 1992 1182 1187
12. C. Halle, M. Lando, D.H. Svendsrud, T. Clancy, M. Holden, and K. Sundfor Membranous expression of ectodomain isoforms of the epidermal growth factor receptor predicts outcome after chemoradiotherapy of lymph node-negative cervical cancer Clin Cancer Res 17 2011 5501 5512
13. T. Soonthornthum, H. Arias-Pulido, N. Joste, L. Lomo, C. Muller, and T. Rutledge Epidermal growth factor receptor as a biomarker for cervical cancer Ann Oncol 22 2011 2166 2178
14. H. Arias-Pulido, N. Joste, A. Chavez, C.Y. Muller, D. Dai, and H.O. Smith Absence of epidermal growth factor receptor mutations in cervical cancer Int J Gynecol Cancer 18 2008 749 754
15. J.C. Barrett, B. Fry, J. Maller, and M.J. Daly Haploview: analysis and visualization of LD and haplotype maps Bioinformatics 21 2005 263 265
16. D. Clayton, and H.B. Jones Transmission/disequilibrium tests for extended marker haplotypes Am J Hum Genet 65 1999 1161 1169
17. A.D. Skol, L.J. Scott, G.R. Abecasis, and M. Boehnke Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies Nat Genet 38 2006 209 213
18. J.M. McInerney, M.A. Wilson, K.J. Strand, and S.A. Chrysogelos A strong intronic enhancer element of the EGFR gene is preferentially active in high EGFR expressing breast cancer cells J Cell Biochem 80 2001 538 549
19. B. Brandt, S. Meyer-Staeckling, H. Schmidt, K. Agelopoulos, and H. Buerger Mechanisms of egfr gene transcription modulation: relationship to cancer risk and therapy response Clin Cancer Res 12 2006 7252 7260
20. S.A. Chrysogelos Chromatin structure of the EGFR gene suggests a role for intron 1 sequences in its regulation in breast cancer cells Nucleic Acids Res 21 1993 5736 5741
21. W. Liu, L. He, J. Ramirez, S. Krishnaswamy, R. Kanteti, and Y.C. Wang Functional EGFR germline polymorphisms may confer risk for EGFR somatic mutations in non-small cell lung cancer, with a predominant effect on exon 19 microdeletions Cancer Res 71 2011 2423 2427
22. W. Liu, F. Innocenti, M.H. Wu, A.A. Desai, M.E. Dolan, and E.H. Cook Jr. A functional common polymorphism in a Sp1 recognition site of the epidermal growth factor receptor gene promoter Cancer Res 65 2005 46 53
23. A. Araujo, R. Ribeiro, I. Azevedo, A. Coelho, M. Soares, and B. Sousa Genetic polymorphisms of the epidermal growth factor and related receptor in non-small cell lung cancer - a review of the literature Oncologist 12 2007 201 210
24. H. Buerger, F. Gebhardt, H. Schmidt, A. Beckmann, K. Hutmacher, and R. Simon Length and loss of heterozygosity of an intron 1 polymorphic sequence of egfr is related to cytogenetic alterations and epithelial growth factor receptor expression Cancer Res 60 2000 854 857
25. F. Gebhardt, K.S. Zanker, and B. Brandt Modulation of epidermal growth factor receptor gene transcription by a polymorphic dinucleotide repeat in intron 1 J Biol Chem 274 1999 13176 13180
26. N. Tidow, A. Boecker, H. Schmidt, K. Agelopoulos, W. Boecker, and H. Buerger Distinct amplification of an untranslated regulatory sequence in the egfr gene contributes to early steps in breast cancer development Cancer Res 63 2003 1172 1178
27. B. Brandt, S. Hermann, K. Straif, N. Tidow, H. Buerger, and J. Chang-Claude Modification of breast cancer risk in young women by a polymorphic sequence in the egfr gene Cancer Res 64 2004 7 12
28. W. Zhang, J.L. Weissfeld, M. Romkes, S.R. Land, J.R. Grandis, and J.M. Siegfried Association of the EGFR intron 1 CA repeat length with lung cancer risk Mol Carcinog 46 2007 372 380
29. N. Sueoka-Aragane, K. Imai, K. Komiya, A. Sato, R. Tomimasu, and T. Hisatomi Exon 19 of EGFR mutation in relation to the CA-repeat polymorphism in intron 1 Cancer Sci 99 2008 1180 1187
30. H. Brustmann, S. Hinterholzer, and A. Brunner Expression of phosphorylated histone H2AX (gamma-H2AX) in normal and neoplastic squamous epithelia of the uterine cervix: an immunohistochemical study with epidermal growth factor receptor Int J Gynecol Pathol 30 2011 76 83
31. S.C. Kim, H.M. Park, S.N. Lee, and W.S. Han Expression of epidermal growth factor receptor in cervical tissue and serum in patients with cervical neoplasia J Low Genit Tract Dis 8 2004 292 297
32. C.D. Woodworth, D. Gaiotti, E. Michael, L. Hansen, and M. Nees Targeted disruption of the epidermal growth factor receptor inhibits development of papillomas and carcinomas from human papillomavirus-immortalized keratinocytes Cancer Res 60 2000 4397 4402
33. S.M. Genther Williams, G.L. Disbrow, R. Schlegel, D. Lee, D.W. Threadgill, and P.F. Lambert Requirement of epidermal growth factor receptor for hyperplasia induced by E5, a high-risk human papillomavirus oncogene Cancer Res 65 2005 6534 6542
34. A. Venuti, F. Paolini, L. Nasir, A. Corteggio, S. Roperto, and M.S. Campo Papillomavirus E5: the smallest oncoprotein with many functions Mol Cancer 10 2011 140
35. S.L. Chen, S.T. Lin, T.C. Tsai, W.C. Hsiao, and Y.P. Tsao ErbB4 (JM-b/CYT-1)-induced expression and phosphorylation of c-Jun is abrogated by human papillomavirus type 16 E5 protein Oncogene 26 2007 42 53
36. J.L. Chang, Y.P. Tsao, D.W. Liu, C.P. Han, W.H. Lee, and S.L. Chen The expression of type I growth factor receptors in the squamous neoplastic changes of uterine cervix Gynecol Oncol 73 1999 62 71
37. J.L. Chang, Y.P. Tsao, D.W. Liu, S.J. Huang, W.H. Lee, and S.L. Chen The expression of HPV-16 E5 protein in squamous neoplastic changes in the uterine cervix J Biomed Sci 8 2001 206 213