Identification of drug-related problems by a clinical pharmacist in addition to computerized alerts

International Journal of Clinical Pharmacy

Volumn 35, Issue 5, 2013, Pages 753-762

  Zaal, Rianne J ^a   Jansen, Mark M P M ^b   Duisenberg Van Essenberg, Marjolijn ^b   Tijssen, Cees C ^b   Roukema, Jan A ^b   Van Den Bemt, Patricia M L A ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b Microvida Laboratory for Medical Microbiology and Immunology   (Netherlands)

Author keywords

Adverse drug events; Clinical decision support system; Clinical pharmacist; Computerized physician order entry; Medication errors; The Netherlands

Indexed keywords

ADULT; ADVERSE DRUG REACTION; AGED; ARTICLE; COMPUTERIZED PROVIDER ORDER ENTRY; DECISION SUPPORT SYSTEM; DRUG EFFICACY; DRUG INDICATION; DRUG RELATED PROBLEMS; DRUG SAFETY; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICATION ERROR; NETHERLANDS; OBSERVATIONAL STUDY; OUTCOME ASSESSMENT; PHARMACEUTICAL CARE; PHARMACIST; PRIORITY JOURNAL; PROSPECTIVE STUDY; TEACHING HOSPITAL; WARD;

AGED; AGED, 80 AND OVER; DECISION SUPPORT SYSTEMS, CLINICAL; DRUG MONITORING; DRUG THERAPY, COMPUTER-ASSISTED; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; FEMALE; FOLLOW-UP STUDIES; HOSPITALS, TEACHING; HUMANS; MALE; MEDICATION ERRORS; MIDDLE AGED; MODELS, BIOLOGICAL; NETHERLANDS; NEUROLOGY; PHARMACISTS; PHARMACOLOGY, CLINICAL; PHARMACY SERVICE, HOSPITAL; REFERRAL AND CONSULTATION; RISK; SURGERY DEPARTMENT, HOSPITAL;

EID: 84886097972     PISSN: 22107703     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11096-013-9798-4     Document Type: Article

References (46)

1. Hoonhout LH, de Bruijne MC, Wagner C, Asscheman H, van der Wal G, van Tulder MW. Nature, occurrence and consequences of medication-related adverse events during hospitalization: a retrospective chart review in the Netherlands. Drug Saf. 2010;33(10):853-64.
2. Krahenbuhl-Melcher A, Schlienger R, Lampert M, Haschke M, Drewe J, Krahenbuhl S. Drug-related problems in hospitals: a review of the recent literature. Drug Saf. 2007;30(5):379-407.
3. IOM (Institute of Medicine). To err is human: building a safer health system. Washington: National Academy Press; 2000. ISBN 978-0-309-26174-6.
4. Classen DC, Resar R, Griffin F, Federico F, Frankel T, Kimmel N, et al. 'Global trigger tool' shows that adverse events in hospitals may be ten times greater than previously measured. Health Aff (Millwood). 2011;30(4):581-9.
5. Landrigan CP, Parry GJ, Bones CB, Hackbarth AD, Goldmann DA, Sharek PJ. Temporal trends in rates of patient harm resulting from medical care. N Engl J Med. 2010;363(22):2124-34.
6. IOM (Institute of Medicine). Health IT and patient safety: building safer systems for better care. Washington: The National Academies Press; 2012. ISBN 978-0-309-22112-2.
7. Bates DW, Miller EB, Cullen DJ, Burdick L, Williams L, Laird N, et al. Patient risk factors for adverse drug events in hospitalized patients. ADE Prevention Study Group. Arch Intern Med. 1999;159(21):2553-60.
8. Dean B, Schachter M, Vincent C, Barber N. Causes of prescribing errors in hospital inpatients: a prospective study. Lancet. 2002;359(9315):1373-8.
9. Leape LL, Bates DW, Cullen DJ, Cooper J, Demonaco HJ, Gallivan T, et al. Systems analysis of adverse drug events. ADE Prevention Study Group. JAMA. 1995;274(1):35-43.
10. Lesar TS, Briceland L, Stein DS. Factors related to errors in medication prescribing. JAMA. 1997;277(4):312-7.
11. Zaal RJ, van Doormaal JE, Lenderink AW, Mol PG, Kosterink JG, Egberts TC, et al. Comparison of potential risk factors for medication errors with and without patient harm. Pharmacoepidemiol Drug Saf. 2010;19(8):825-33.
12. Coiera E, Aarts J, Kulikowski C. The dangerous decade. J Am Med Inform Assoc. 2012;19(1):2-5.
13. Ammenwerth E, Schnell-Inderst P, Machan C, Siebert U. The effect of electronic prescribing on medication errors and adverse drug events: a systematic review. J Am Med Inform Assoc. 2008;15(5):585-600.
14. Bates DW, Leape LL, Cullen DJ, Laird N, Petersen LA, Teich JM, et al. Effect of computerized physician order entry and a team intervention on prevention of serious medication errors. JAMA. 1998;280(15):1311-6.
15. Eslami S, de Keizer NF, Abu-Hanna A. The impact of computerized physician medication order entry in hospitalized patients - a systematic review. Int J Med Inform. 2008;77(6):365-76.
16. Kaushal R, Shojania KG, Bates DW. Effects of computerized physician order entry and clinical decision support systems on medication safety: a systematic review. Arch Intern Med. 2003;163(12):1409-16.
17. Rommers MK, Teepe-Twiss IM, Guchelaar HJ. A computerized adverse drug event alerting system using clinical rules: a retrospective and prospective comparison with conventional medication surveillance in the Netherlands. Drug Saf. 2011;34(3):233-42.
18. Shamliyan TA, Duval S, Du J, Kane RL. Just what the doctor ordered. Review of the evidence of the impact of computerized physician order entry system on medication errors. Health Serv Res. 2008;43(1 Pt 1):32-53.
19. van Doormaal JE, Rommers MK, Kosterink JG, Teepe-Twiss IM, Haaijer-Ruskamp FM, Mol PG. Comparison of methods for identifying patients at risk of medication-related harm. Qual Saf Health Care. 2010;19(6):e26.
20. van Doormaal JE, van den Bemt PMLA, Zaal RJ, Egberts AC, Lenderink BW, Kosterink JG, et al. The influence that electronic prescribing has on medication errors and preventable adverse drug events: an interrupted time-series study. J Am Med Inform Assoc. 2009;16(6):816-25.
21. van Doormaal JE, van den Bemt PMLA, Mol PG, Zaal RJ, Egberts AC, Haaijer-Ruskamp FM, et al. Medication errors: the impact of prescribing and transcribing errors on preventable harm in hospitalised patients. Qual Saf Health Care. 2009;18(1):22-7.
22. van der Sijs H, Aarts J, Vulto A, Berg M. Overriding of drug safety alerts in computerized physician order entry. J Am Med Inform Assoc. 2006;13(2):138-47.
23. Bedouch P, Allenet B, Grass A, Labarere J, Brudieu E, Bosson JL, et al. Drug-related problems in medical wards with a computerized physician order entry system. J Clin Pharm Ther. 2009;34(2):187-95.
24. Bosma L, Jansman FG, Franken AM, Harting JW, Van den Bemt PMLA. Evaluation of pharmacist clinical interventions in a Dutch hospital setting. Pharm World Sci. 2008;30(1):31-8.
25. Boyko WL Jr, Yurkowski PJ, Ivey MF, Armitstead JA, Roberts BL. Pharmacist influence on economic and morbidity outcomes in a tertiary care teaching hospital. Am J Health Syst Pharm. 1997;54(14):1591-5.
26. Buck TC, Brandstrup L, Brandslund I, Kampmann JP. The effects of introducing a clinical pharmacist on orthopaedic wards in Denmark. Pharm World Sci. 2007;29(1):12-8.
27. Kaboli PJ, Hoth AB, McClimon BJ, Schnipper JL. Clinical pharmacists and inpatient medical care: a systematic review. Arch Intern Med. 2006;166(9):955-64.
28. Klopotowska JE, Kuiper R, van Kan HJ, de Pont AC, Dijkgraaf MG, Lie-A-Huen L, et al. On-ward participation of a hospital pharmacist in a Dutch intensive care unit reduces prescribing errors and related patient harm: an intervention study. Crit Care. 2010;14(5):R174.
29. Kopp BJ, Mrsan M, Erstad BL, Duby JJ. Cost implications of and potential adverse events prevented by interventions of a critical care pharmacist. Am J Health Syst Pharm. 2007;64(23):2483-7.
30. Makowsky MJ, Koshman SL, Midodzi WK, Tsuyuki RT. Capturing outcomes of clinical activities performed by a rounding pharmacist practicing in a team environment: the COLLABORATE study [NCT00351676]. Med Care. 2009;47(6):642-50.
31. Rommers MK, Teepe-Twiss IM, Guchelaar HJ. Preventing adverse drug events in hospital practice: an overview. Pharmacoepidemiol Drug Saf. 2007;16(10):1129-35.
32. Scarsi KK, Fotis MA, Noskin GA. Pharmacist participation in medical rounds reduces medication errors. Am J Health Syst Pharm. 2002;59(21):2089-92.
33. de Vries EN, Ramrattan MA, Smorenburg SM, Gouma DJ, Boermeester MA. The incidence and nature of in-hospital adverse events: a systematic review. Qual Saf Health Care. 2008;17(3):216-23.
34. Fijn R, Van den Bemt PMLA, Chow M, De Blaey CJ, De Jong-Van den Berg LT, Brouwers JR. Hospital prescribing errors: epidemiological assessment of predictors. Br J Clin Pharmacol. 2002;53(3):326-31.
35. van Roon EN, Flikweert S, le Comte M, Langendijk PN, Kwee-Zuiderwijk WJ, Smits P, et al. Clinical relevance of drug-drug interactions: a structured assessment procedure. Drug Saf. 2005;28(12):1131-9.
36. van den Bemt PMLA, Egberts TC, De Jong-Van den Berg LT, Brouwers JR. Drug-related problems in hospitalised patients. Drug Saf. 2000;22(4):321-33.
37. Leendertse AJ, de Koning FH, Goudswaard AN, Jonkhoff AR, van den Bogert SC, de Gier HJ, et al. Preventing hospital admissions by reviewing medication (PHARM) in primary care: design of the cluster randomised, controlled, multi-centre PHARM-study. BMC Health Serv Res. 2011;11(1):4.
38. Strand LM, Morley PC, Cipolle RJ, Ramsey R, Lamsam GD. Drug-related problems: their structure and function. DICP. 1990;24(11):1093-7.
39. van den Bemt PMLA, van den Broek S, van Nunen AK, Harbers JB, Lenderink AW. Medication reconciliation performed by pharmacy technicians at the time of preoperative screening. Ann Pharmacother. 2009;43(5):868-74.
40. National Coordinating Council for Medication Error Reporting and Preventing. NCC MERP Index for Categorizing Medication Errors. www.nccmerp.org/pdf/indexColor2001-06-12.pdf. Accessed 5 April 2012.
41. van Doormaal JE, Mol PG, van den Bemt PMLA, Zaal RJ, Egberts AC, Kosterink JG, et al. Reliability of the assessment of preventable adverse drug events in daily clinical practice. Pharmacoepidemiol Drug Saf. 2008;17(7):645-54.
42. Bedouch P, Tessier A, Baudrant M, Labarere J, Foroni L, Calop J, et al. Computerized physician order entry system combined with on-ward pharmacist: analysis of pharmacists' interventions. J Eval Clin Pract. 2012;18(4):911-8.
43. Nebeker JR, Hoffman JM, Weir CR, Bennett CL, Hurdle JF. High rates of adverse drug events in a highly computerized hospital. Arch Intern Med. 2005;165(10):1111-6.
44. Chisholm-Burns MA, Kim Lee J, Spivey CA, Slack M, Herrier RN, Hall-Lipsy E, et al. US pharmacists' effect as team members on patient care: systematic review and meta-analyses. Med Care. 2010;48(10):923-33.
45. Eppenga WL, Derijks HJ, Conemans JM, Hermens WA, Wensing M, De Smet PA. Comparison of a basic and an advanced pharmacotherapy-related clinical decision support system in a hospital care setting in the Netherlands. J Am Med Inform Assoc. 2012;19(1):66-71.
46. Scheepers-Hoeks AM, Grouls RJ, Neef C, Korsten HH. Strategy for implementation and first results of advanced clinical decision support in hospital pharmacy practice. Stud Health Technol Inform. 2009;148:142-8.