A computerized adverse drug event alerting system using clinical rules: A retrospective and prospective comparison with conventional medication surveillance in the Netherlands

Drug Safety

Volumn 34, Issue 3, 2011, Pages 233-242

  Rommers, Mirjam K ^a   Teepe Twiss, Irene M ^a   Guchelaar, Henk Jan ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Adverse reaction monitoring; Drug interactions; E prescribing; Medication errors; Pharmaceutical services; Prescribing

Indexed keywords

ARTICLE; COMPUTERIZED PROVIDER ORDER ENTRY; DECISION SUPPORT SYSTEM; DRUG SAFETY; DRUG SURVEILLANCE PROGRAM; HOSPITAL ADMISSION; HUMAN; INTENSIVE CARE UNIT; KIDNEY FUNCTION; NETHERLANDS; PRIORITY JOURNAL; PROSPECTIVE STUDY; RETROSPECTIVE STUDY; UNIVERSITY HOSPITAL;

ADVERSE DRUG REACTION REPORTING SYSTEMS; DECISION SUPPORT SYSTEMS, CLINICAL; HOSPITALS, UNIVERSITY; HUMANS; MEDICAL ORDER ENTRY SYSTEMS; NETHERLANDS; PHARMACEUTICAL PREPARATIONS; PHARMACISTS; PHARMACY SERVICE, HOSPITAL; PROSPECTIVE STUDIES; RETROSPECTIVE STUDIES;

EID: 79951805108     PISSN: 01145916     EISSN: 11791942     Source Type: Journal    
DOI: 10.2165/11536500-000000000-00000     Document Type: Article

References (29)

1. Krahenbuhl-Melcher A, Schlienger R, Lampert M, et al. Drug-related problems in hospitals: a review of the recent literature. Drug Saf 2007; 30 (5): 379-407 (Pubitemid 46740336)
2. Kaushal R, Shojania KG, Bates DW. Effects of computer- ized physician order entry and clinical decision support systems on medication safety: a systematic review. Arch Intern Med 2003 Jun; 163 (12): 1409-16 (Pubitemid 36758913)
3. Rommers MK, Teepe-Twiss IM, Guchelaar HJ. Preventing adverse drug events in hospital practice: an overview. Pharmacoepidemiol Drug Saf 2007 Oct; 16 (10): 1129-35 (Pubitemid 350020066)
4. Classen DC, Pestotnik SL, Evans RS, et al. Computerized surveillance of adverse drug events in hospital patients. JAMA 1991 Nov; 266 (20): 2847-51
5. Jha AK, Kuperman GJ, Teich JM, et al. Identifying adverse drug events: development of a computer-based monitor and comparison with chart review and stimulated voluntary report. J Am Med Inform Assoc 1998 May; 5 (3): 305-14 (Pubitemid 28222037)
6. Raschke RA, Gollihare B, Wunderlich TA, et al. A com- puter alert system to prevent injury from adverse drug events: development and evaluation in a community teaching hospital. JAMA 1998 Oct; 280 (15): 1317-20 (Pubitemid 28473717)
7. Silverman JB, Stapinski CD, Huber C, et al. Computer- based system for preventing adverse drug events. Am J Health Syst Pharm 2004 Aug; 61 (15): 1599-603 (Pubitemid 39481403)
8. Ammenwerth E, Schnell-Inderst P, Machan C, et al. The effect of electronic prescribing on medication errors and adverse drug events: a systematic review. J Am Med Inform Assoc 2008 Sep; 15 (5): 585-600
9. Chaudhry B, Wang J, Wu S, et al. Systematic review: impact of health information technology on quality, efficiency, and costs of medical care. Ann Intern Med 2006 May; 144 (10): 742-52 (Pubitemid 46780634)
10. Eslami S, de Keizer NF, bu-Hanna A. The impact of computerized physician medication order entry in hospitalized patients: a systematic review. Int J Med Inform 2008 Jun; 77 (6): 365-76 (Pubitemid 351626710)
11. Shamliyan TA, Duval S, Du J, et al. Just what the doctor ordered: review of the evidence of the impact of computerized physician order entry system on medication errors. Health Serv Res 2008 Feb; 43 (1 Pt 1): 32-53 (Pubitemid 351601525)
12. Wolfstadt JI, Gurwitz JH, Field TS, et al. The effect of computerized physician order entry with clinical decision support on the rates of adverse drug events: a systematic review. J Gen Intern Med 2008 Apr; 23 (4): 451-8 (Pubitemid 351464877)
13. Kalmeijer MD, Holtzer W, van Dongen R, et al. Implemen- tation of a computerized physician medication order entry system at the Academic Medical Centre in Amsterdam. Pharm World Sci 2003 Jun; 25 (3): 88-93 (Pubitemid 36749798)
14. Guchelaar HJ, Kalmeijer MD. The potential role of com- puterisation and information technology in improving prescribing in hospitals. Pharm World Sci 2003 Jun; 25 (3): 83-7 (Pubitemid 36749797)
15. van der Sijs H, Aarts J, Vulto A, et al. Overriding of drug safety alerts in computerized physician order entry. J Am Med Inform Assoc 2006 Mar; 13 (2): 138-47 (Pubitemid 43332904)
16. van Doormaal JE, van den Bemt PM, Zaal RJ, et al. The influence that electronic prescribing has on medication errors and preventable adverse drug events: an interrupted time-series study. J Am Med Inform Assoc 2009 Nov; 16 (6): 816-25
17. Rommers MK, Zegers MH, De Clercq PA, et al. Develop- ment of a computerized adverse drug event alerting system (ADEAS) to identify patients at risk for an adverse drug event. Qual Saf Health Care 2010 Dec; 19 (6): e35
18. van Doormaal JE, Rommers MK, Kosterink JGW, et al. Comparison of methods for identifying patients at risk of medication-related harm. Qual Saf Health Care 2010 Dec; 19 (6): e26
19. Goldberg DE, Baardsgaard G, Johnson MT, et al. Compu- ter-based program for identifying medication orders requiring dosage modification based on renal function. Am J Hosp Pharm 1991 Sep; 48 (9): 1965-9
20. Kane-Gill SL, Dasta JF, Schneider PJ, et al. Monitoring abnormal laboratory values as antecedents to drug-induced injury. J Trauma 2005 Dec; 59 (6): 1457-62
21. Peterson JP, Colucci VJ, Schiff SE. Using serum creatinine concentrations to screen for inappropriate dosage of ren-ally eliminated drugs. Am J Hosp Pharm 1991 Sep; 48 (9): 1962-4
22. Schiff GD, Aggarwal HC, Kumar S, et al. Prescribing po- tassium despite hyperkalemia: medication errors uncovered by linking laboratory and pharmacy information systems. Am J Med 2000 Oct; 109 (6): 494-7
23. Schiff GD, Klass D, Peterson J, et al. Linking laboratory and pharmacy: opportunities for reducing errors and improving care. Arch Intern Med 2003 Apr; 163 (8): 893-900 (Pubitemid 36519735)
24. van der Sijs H, Aarts J, van GT, et al. Turning off frequently overridden drug alerts: limited opportunities for doing it safely. J Am Med Inform Assoc 2008 Jul; 15 (4): 439-48
25. Jha AK, Laguette J, Seger A, et al. Can surveillance systems identify and avert adverse drug events? A prospective evaluation of a commercial application. J Am Med Inform Assoc 2008 Sep; 15 (5): 647-53
26. Kilbridge PM, Alexander L, Ahmad A. Implementation of a system for computerized adverse drug event surveillance and intervention at an academic medical center. J Clin Outcomes Manag 2006; 13 (2): 94-100
27. Kilbridge PM, Campbell UC, Cozart HB, et al. Automated surveillance for adverse drug events at a community hospital and an academic medical center. J Am Med Inform Assoc 2006 Jul; 13 (4): 372-7 (Pubitemid 43947628)
28. Seger AC, Jha AK, Bates DW. Adverse drug event detection in a community hospital utilising computerised medication and laboratory data. Drug Saf 2007; 30 (9): 817-24 (Pubitemid 47347354)
29. Kaboli PJ, Hoth AB, McClimon BJ, et al. Clinical phar- macists and inpatient medical care: a systematic review. Arch Intern Med 2006 May; 166 (9): 955-64