Comparison of a basic and an advanced pharmacotherapy-related clinical decision support system in a hospital care setting in the Netherlands

Journal of the American Medical Informatics Association

Volumn 19, Issue 1, 2012, Pages 66-71

  Eppenga, Willemijn L ^a,b   Derijks, Hieronymus J ^a,c   Conemans, Jean M H ^a   Hermens, Walter A J J ^a   Wensing, Michel ^b   De Smet, Peter A G M ^b  

^a IQ healthcare   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ALGORITHM; ARTICLE; CLINICAL DECISION MAKING; COMPARATIVE STUDY; CONTROLLED STUDY; DECISION SUPPORT SYSTEM; FEMALE; HOSPITAL CARE; HOSPITAL PATIENT; HUMAN; LABORATORY TEST; MAJOR CLINICAL STUDY; MALE; MEDICATION THERAPY MANAGEMENT; NETHERLANDS; PHARMACIST; PRACTICE GUIDELINE; PREDICTIVE VALUE;

CLINICAL PHARMACY INFORMATION SYSTEMS; DECISION SUPPORT SYSTEMS, CLINICAL; HUMANS; MEDICAL ORDER ENTRY SYSTEMS; MEDICATION SYSTEMS, HOSPITAL; NETHERLANDS; OBSERVATION; PHARMACY SERVICE, HOSPITAL; PROSPECTIVE STUDIES;

EID: 84856773795     PISSN: 10675027     EISSN: 1527974X     Source Type: Journal    
DOI: 10.1136/amiajnl-2011-000360     Document Type: Article

References (34)

1. Leendertse AJ, Egberts AC, Stoker LJ, et al. Frequency of and risk factors for preventable medication-related hospital admissions in the Netherlands. Arch Intern Med 2008;168:1890-6.
2. Warlé-Van Herwaarden MF, Kramers C, Sturkenboom MC, et al. Targeting outpatient drug safety: recommendations of the Dutch HARM-wrestling task force. http://www.knmp.nl/downloads/medicijnen-zorgverlening/medicatieveiligheid/harmwrestlingEnglish.pdf.
3. De Smet PA, Denneboom W, Kramers C, et al. A composite screening tool for medication reviews of outpatients: general issues with specific examples. Drugs Aging 2007;24:733-60.
4. van der Sijs H, Aarts J, Vulto A, et al. Overriding of drug safety alerts in computerized physician order entry. J Am Med Inform Assoc 2006;13:138-47.
5. Isaac T, Weissman JS, Davis RB, et al. Overrides of medication alerts in ambulatory care. Arch Intern Med 2009;169:305-11.
6. Judge J, Field TS, DeFlorio M, et al. Prescribers' responses to alerts during medication ordering in the long term care setting. J Am Med Inform Assoc 2006;13:385-90.
7. Geerts AF, De Koning FH, De Smet PA, et al. Laboratory tests in the clinical risk management of potential drug-drug interactions: a cross-sectional study using drug-dispensing data from 100 Dutch community pharmacies. Drug Saf 2009;32:1189-97.
8. Galanter WL, Polikaitis A, Didomenico RJ. A trial of automated safety alerts for inpatient digoxin use with computerized physician order entry. J Am Med Inform Assoc 2004;11:270-7.
9. Raebel MA, Chester EA, Newsom EE, et al. Randomized trial to improve laboratory safety monitoring of ongoing drug therapy in ambulatory patients. Pharmacotherapy 2006;26:619-26.
10. Shah KB, Rao K, Sawyer R, et al. The adequacy of laboratory monitoring in patients treated with spironolactone for congestive heart failure. J Am Coll Cardiol 2005;46:845-9.
11. Handler SM, Hanlon JT, Perera S, et al. Assessing the performance characteristics of signals used by a clinical event monitor to detect adverse drug reactions in the nursing home. AMIA Annu Symp Proc 2008:278-82.
12. Seger AC, Jha AK, Bates DW. Adverse drug event detection in a community hospital utilising computerised medication and laboratory data. Drug Saf 2007;30:817-24.
13. Wright A, Sittig DF, Ash JS, et al. Clinical decision support capabilities of commercially-available clinical information systems. J Am Med Inform Assoc 2009;16:637-44.
14. Swen JJ, Wilting I, de Goede AL, et al. Pharmacogenetics: from bench to byte. Clin Pharmacol Ther 2008;83:781-7.
15. van Roon EN, Flikweert S, le CM, et al. Clinical relevance of drug-drug interactions: a structured assessment procedure. Drug Saf 2005;28:1131-9.
16. van der Sijs H, Aarts J, van GT, et al. Turning off frequently overridden drug alerts: limited opportunities for doing it safely. J Am Med Inform Assoc 2008;15:439-48.
17. Moisa A, Fritz P, Benz D, et al. Iatrogenically-related, fatal methotrexate intoxication: a series of four cases. Forensic Sci Int 2006;156:154-7.
18. Kuperman GJ, Bobb A, Payne TH, et al. Medication-related clinical decision support in computerized provider order entry systems: a review. J Am Med Inform Assoc 2007;14:29-40.
19. Anon. [KNMP Kennisbank]. The Netherlands: Royal Dutch Association for the Advancement of Pharmacy, 2011.
20. van Doormaal JE, Rommers MK, Kosterink JG, et al. Comparison of methods for identifying patients at risk of medication-related harm. Qual Saf Health Care 2010;19: e26.
21. Anon. [The Dutch Institute for Health Care improvement (CBO) guideline NSAID Use and Prevention of Gastric Damage]. Utrecht: The Dutch Institute for Health Care improvement CBO, 2003.
22. Ho PM, Maddox TM, Wang L, et al. Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome. JAMA 2009;301:937-44.
23. Bhatt DL, Cryer BL, Contant CF, et al. Clopidogrel with or without omeprazole in coronary artery disease. N Engl J Med 2010;363:1909-17.
24. Murphy JE, Forrey RA, Desiraju U. Community pharmacists' responses to drug-drug interaction alerts. Am J Health Syst Pharm 2004;61:1484-7.
25. Wessels-Basten SJ, Scheepers-Hoeks AM, Scherders MJ, et al. Reuzenstap in verbetering medicatiebewaking. Pharm Weekbl 2009;3:20-3.
26. Handler SM, Altman RL, Perera S, et al. A systematic review of the performance characteristics of clinical event monitor signals used to detect adverse drug events in the hospital setting. J Am Med Inform Assoc 2007;14:451-8.
27. Raschke RA, Gollihare B, Wunderlich TA, et al. A computer alert system to prevent injury from adverse drug events: development and evaluation in a community teaching hospital. JAMA 1998;280:1317-20.
28. van der Sijs H, Bouamar R, van GT, et al. Functionality test for drug safety alerting in computerized physician order entry systems. Int J Med Inform 2010;79: 243-51.
29. Saverno KR, Hines LE, Warholak TL, et al. Ability of pharmacy clinical decisionsupport software to alert users about clinically important drug-drug interactions. J Am Med Inform Assoc. 2011;18:32-7.
30. Hines LE, Saverno KR, Warholak TL, et al. Pharmacists' awareness of clinical decision support in pharmacy information systems: an exploratory evaluation. Res Social Adm Pharm. Published Online First 2011. doi:10.1016/j.sapharm.2010.10.007.
31. Sim I, Gorman P, Greenes RA, et al. Clinical decision support systems for the practice of evidence-based medicine. J Am Med Inform Assoc 2001;8:527-34.
32. Kurnik D, Lubetsky A, Loebstein R, et al. Multivitamin supplements may affect warfarin anticoagulation in susceptible patients. Ann Pharmacother 2003;37:1603-6.
33. Kurnik D, Loebstein R, Rabinovitz H, et al. Over-the-counter vitamin K1-containing multivitamin supplements disrupt warfarin anticoagulation in vitamin K1-depleted patients. A prospective, controlled trial. Thromb Haemost 2004;92:1018-24.
34. Loeffen ML, Katen ten M, Scheepers-Hoeks AMJW, et al. Prevention of opioid induced constipation using a clinical rule. Br J Clin Pharmacol 2009;68:133.