Synthesis and characterization of Pt(iv) fluorescein conjugates to investigate Pt(iv) intracellular transformations

Bioconjugate Chemistry

Volumn 24, Issue 10, 2013, Pages 1733-1740

  Song, Ying ^a   Suntharalingam, Kogularamanan ^a   Yeung, Jessica S ^a   Royzen, Maksim ^a   Lippard, Stephen J ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL DEATH; DISEASES; DNA; LIGANDS; PLATINUM COMPOUNDS; REDUCING AGENTS;

% REDUCTIONS; ANTICANCER COMPOUNDS; AXIAL LIGAND; CANCER CELLS; CIS-PLATIN; CISPLATIN; HYPOXIC ENVIRONMENTS; PRODRUGS; REDUCTION PROCESS; SYNTHESIS AND CHARACTERIZATIONS;

FLUORESCENCE;

ASCORBIC ACID; CISPLATIN; FLUORESCEIN; FLUORESCEIN ISOTHIOCYANATE; GENOMIC DNA; GLUTATHIONE; HISTONE H2AX; LIGAND; PHOSPHATE BUFFERED SALINE; PLATINUM; PRODRUG;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL DEATH; CELL MEMBRANE PERMEABILITY; CELL VIABILITY; CHROMATOPHORE; CONJUGATE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DRUG SYNTHESIS; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LIQUID CHROMATOGRAPHY; LYSOSOME; M PHASE CELL CYCLE CHECKPOINT; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTUM YIELD; S PHASE CELL CYCLE CHECKPOINT;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL SURVIVAL; CISPLATIN; FLUORESCEIN; HUMANS; NEOPLASMS; OPTICAL IMAGING; OXIDATION-REDUCTION; PRODRUGS;

EID: 84886067517     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc400281a     Document Type: Article

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