Immune senescence and cancer in elderly patients: Results from an exploratory study

Experimental Gerontology

Volumn 48, Issue 12, 2013, Pages 1436-1442

  Falci, Cristina ^a   Gianesin, Ketty ^b   Sergi, Giuseppe ^b   Giunco, Silvia ^a   De Ronch, Irene ^b   Valpione, Sara ^b   Soldà, Caterina ^a   Fiduccia, Pasquale ^a   Lonardi, Sara ^a   Zanchetta, Marisa ^a   Keppel, Sonia ^a   Brunello, Antonella ^a   Zafferri, Valeria ^a   Manzato, Enzo ^b   De Rossi, Anita ^a,b   Zagonel, Vittorina ^a  

^a VENETO INSTITUTE OF ONCOLOGY IOV IRCCS   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

Author keywords

Cancer; Elderly; Immune senescence; Telomerase activity; Telomere length; Thymic output

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; T LYMPHOCYTE RECEPTOR; TELOMERASE;

AGED; ARTICLE; BLOOD ANALYSIS; BREAST CANCER; CANCER PATIENT; CANCER RISK; CANCER STAGING; CANCER SURGERY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHROMOSOME SIZE; COLORECTAL CANCER; COMPREHENSIVE GERIATRIC ASSESSMENT; CONTROLLED STUDY; ELDERLY CARE; ENZYME ACTIVITY; EXPLORATORY RESEARCH; FEMALE; FLOW CYTOMETRY; GENE STRUCTURE; GERIATRIC PATIENT; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNE SENESCENCE; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROGNOSIS; PROSPECTIVE STUDY; REAL TIME POLYMERASE CHAIN REACTION; SCORING SYSTEM; T CELL RECEPTOR REARRANGEMENT EXCISION CIRCLE; TELOMERE; THYMIC OUTPUT; THYMUS FUNCTION;

ACTIVITIES OF DAILY LIVING; ADL; CANCER; CGA; CIRS-CI; CIRS-SI; CMV; COMPREHENSIVE GERIATRIC ASSESSMENT; CUMULATIVE ILLNESS RATING SCALE-COMORBIDITY INDEX; CUMULATIVE ILLNESS RATING SCALE-SEVERITY INDEX; CYTOMEGALOVIRUS; ELDERLY; GDS; GERIATRIC DEPRESSION SCALE; IADL; IMMUNE SENESCENCE; INSTRUMENTAL ACTIVITIES OF DAILY LIVING; MINI MENTAL STATUS EXAMINATION; MINI NUTRITIONAL ASSESSMENT; MMSE; MNA; MPI; MULTIDIMENSIONAL PROGNOSTIC INDEX; PBMC; PERIPHERAL BLOOD MONONUCLEAR CELLS; RECENT THYMIC EMIGRANT; RELATIVE UNITS; RTE; RU; SHORT PORTABLE MENTAL STATUS QUESTIONNAIRE; SPMSQ; T-CELL RECEPTOR REARRANGEMENT EXCISION CIRCLE; T/S; TELOMERASE ACTIVITY; TELOMERE LENGTH; TELOMERE/SINGLE-COPY GENE; THYMIC OUTPUT; TREC;

AGE FACTORS; AGED; AGED, 80 AND OVER; AGING; BIOLOGICAL MARKERS; BREAST NEOPLASMS; CASE-CONTROL STUDIES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CHI-SQUARE DISTRIBUTION; COLORECTAL NEOPLASMS; FEMALE; FLOW CYTOMETRY; GENE REARRANGEMENT, T-LYMPHOCYTE; GERIATRIC ASSESSMENT; HUMANS; LOGISTIC MODELS; MALE; ODDS RATIO; POLYMERASE CHAIN REACTION; PROSPECTIVE STUDIES; RISK FACTORS; TELOMERASE; TELOMERE SHORTENING; THYMUS GLAND;

EID: 84886032038     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2013.09.011     Document Type: Article

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