Modulation of the cellular distribution of human cytomegalovirus helicase by cellular factor snapin

Journal of Virology

Volumn 87, Issue 19, 2013, Pages 10628-10640

  Luo, Jun ^a   Chen, Jun ^a   Yang, Edward ^b   Shen, Ao ^a,b   Gong, Hao ^b   Pei, Zenglin ^a   Xiao, Gengfu ^a   Lu, Songya ^a   Liu, Fenyong ^b  

^a WUHAN UNIVERSITY   (China)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL FACTOR; CELLULAR FACTOR SNAPIN; HELICASE; PROTEIN ANTIBODY; SMALL INTERFERING RNA; SNAPIN ANTIBODY; UL105 PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; CELL NUCLEUS; CELL VACUOLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; CYTOPLASM; DNA SYNTHESIS; DOWN REGULATION; FETUS; GENE OVEREXPRESSION; GENOMICS; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; HUMAN TISSUE; IMMUNOPRECIPITATION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; TWO HYBRID SYSTEM; VIROGENESIS; VIRUS EXPRESSION; VIRUS GENE;

BLOTTING, WESTERN; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; CYTOPLASM; DNA HELICASES; DNA REPLICATION; DNA, VIRAL; HUMANS; IMMUNOPRECIPITATION; MICROSCOPY, FLUORESCENCE; NEOPLASMS; RNA, SMALL INTERFERING; TUMOR CELLS, CULTURED; TWO-HYBRID SYSTEM TECHNIQUES; VESICULAR TRANSPORT PROTEINS; VIRUS REPLICATION;

EID: 84886025543     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01657-13     Document Type: Article

References (42)

1. Mocarski ES, Shenk T, Pass RF. 2007. Cytomegalovirus, p 2701-2772. In Knipe DM, Howley PM, Griffin DE, Martin MA, Lamb RA, Roizman B, Straus SE (ed), Fields virology, 5th ed. Lippincott William & Wilkins, Philadelphia, PA.
2. Britt WJ. 1999. Congenital cytomegalovirus infection, p 269-281. In Hitchcock H, MacKay T, Wasserheit JN (ed), Sexually transmitted diseases and adverse outcomes of pregnancy. ASM Press, Washington, DC.
3. Britt W. 2008. Manifestations of human cytomegalovirus infection: proposed mechanisms of acute and chronic disease. Curr. Top. Microbiol. Immunol. 325:417-470.
4. Wills MR, Ashiru O, Reeves MB, Okecha G, Trowsdale J, Tomasec P, Wilkinson GW, Sinclair J, Sissons JG. 2005. Human cytomegalovirus encodes an MHC class I-like molecule (UL142) that functions to inhibit NK cell lysis. J. Immunol. 175:7457-7465.
5. Pari GS. 2008. Nuts and bolts of human cytomegalovirus lytic DNA replication. Curr. Top. Microbiol. Immunol. 325:153-166.
6. Biron KK. 2006. Antiviral drugs for cytomegalovirus diseases. Antiviral Res. 71:154-163.
7. Woon HG, Scott GM, Yiu KL, Miles DH, Rawlinson WD. 2008. Identification of putative functional motifs in viral proteins essential for human cytomegalovirus DNA replication. Virus Genes 37:193-202.
8. McMahon TP, Anders DG. 2002. Interactions between human cytomegalovirus helicase-primase proteins. Virus Res. 86:39-52.
9. Smith JA, Jairath S, Crute JJ, Pari GS. 1996. Characterization of the human cytomegalovirus UL105 gene and identification of the putative helicase protein. Virology 220:251-255.
10. Smith JA, Pari GS. 1995. Expression of human cytomegalovirus UL36 and UL37 genes is required for viral DNA replication. J. Virol. 69:1925-1931.
11. Barnard EC, Brown G, Stow ND. 1997. Deletion mutants of the herpes simplex virus type 1 UL8 protein: effect on DNA synthesis and ability to interact with and influence the intracellular localization of the UL5 and UL52 proteins. Virology 237:97-106.
12. Gao Z, Krithivas A, Finan JE, Semmes OJ, Zhou S, Wang Y, Hayward SD. 1998. The Epstein-Barr virus lytic transactivator Zta interacts with the helicase-primase replication proteins. J. Virol. 72:8559-8567.
13. Marsden HS, Cross AM, Francis GJ, Patel AH, MacEachran K, Murphy M, McVey G, Haydon D, Abbotts A, Stow ND. 1996. The herpes simplex virus type 1 UL8 protein influences the intracellular localization of the UL52 but not the ICP8 or POL replication proteins in virus-infected cells. J. Gen. Virol. 77(Pt 9):2241-2249.
14. Penfold ME, Mocarski ES. 1997. Formation of cytomegalovirus DNA replication compartments defined by localization of viral proteins and DNA synthesis. Virology 239:46-61.
15. Alvisi G, Jans DA, Guo J, Pinna LA, Ripalti A. 2005. A protein kinase CK2 site flanking the nuclear targeting signal enhances nuclear transport of human cytomegalovirus ppUL44. Traffic 6:1002-1013.
16. Alvisi G, Ripalti A, Ngankeu A, Giannandrea M, Caraffi SG, Dias MM, Jans DA. 2006. Human cytomegalovirus DNA polymerase catalytic subunit pUL54 possesses independently acting nuclear localization and ppUL44 binding motifs. Traffic 7:1322-1332.
17. Giesen K, Radsak K, Bogner E. 2000. The potential terminase subunit of human cytomegalovirus, pUL56, is translocated into the nucleus by its own nuclear localization signal and interacts with importin alpha. J. Gen. Virol. 81:2231-2244.
18. Pizzorno MC, Mullen MA, Chang YN, Hayward GS. 1991. The functionally active IE2 immediate-early regulatory protein of human cytomegalovirus is an 80-kilodalton polypeptide that contains two distinct activator domains and a duplicated nuclear localization signal. J. Virol. 65: 3839-3852.
19. Wood LJ, Baxter MK, Plafker SM, Gibson W. 1997. Human cytomegalovirus capsid assembly protein precursor (pUL80.5) interacts with itself and with the major capsid protein (pUL86) through two different domains. J. Virol. 71:179-190.
20. Schmolke S, Kern HF, Drescher P, Jahn G, Plachter B. 1995. The dominant phosphoprotein pp65 (UL83) of human cytomegalovirus is dispensable for growth in cell culture. J. Virol. 69:5959-5968.
21. Shen A, Lei J, Yang E, Pei Y, Chen YC, Gong H, Xiao G, Liu F. 2011. Human cytomegalovirus primase UL70 specifically interacts with cellular factor Snapin. J. Virol. 85:11732-11741.
22. Bao Y, Lopez JA, James DE, Hunziker W. 2008. Snapin interacts with the Exo70 subunit of the exocyst and modulates GLUT4 trafficking. J. Biol. Chem. 283:324-331.
23. Buxton P, Zhang XM, Walsh B, Sriratana A, Schenberg I, Manickam E, Rowe T. 2003. Identification and characterization of Snapin as a ubiquitously expressed SNARE-binding protein that interacts with SNAP23 in non-neuronal cells. Biochem. J. 375:433-440.
24. Suzuki F, Morishima S, Tanaka T, Muramatsu I. 2007. Snapin, a new regulator of receptor signaling, augments alpha1A-adrenoceptoroperated calcium influx through TRPC6. J. Biol. Chem. 282:29563-29573.
25. Salsman J, Zimmerman N, Chen T, Domagala M, Frappier L. 2008. Genome-wide screen of three herpesviruses for protein subcellular localization and alteration of PML nuclear bodies. PLoS Pathog. 4:e1000100. doi:10.1371/journal.ppat.1000100.
26. Kilani AF, Trang P, Jo S, Hsu A, Kim J, Nepomuceno E, Liou K, Liu F. 2000. RNase P ribozymes selected in vitro to cleave a viral mRNA effectively inhibit its expression in cell culture. J. Biol. Chem. 275:10611-10622.
27. To A, Bai Y, Shen A, Gong H, Umamoto S, Lu S, Liu F. 2011. Yeast two hybrid analyses reveal novel binary interactions between human cytomegalovirus-encoded virion proteins. PLoS One 6:e17796. doi:10.1371 /journal.pone.0017796.
28. Dunn W, Chou C, Li H, Hai R, Patterson D, Stolc V, Zhu H, Liu F. 2003. Functional profiling of a human cytomegalovirus genome. Proc. Natl. Acad. Sci. U.S.A. 100:14223-14228.
29. Trang P, Lee M, Nepomuceno E, Kim J, Zhu H, Liu F. 2000. Effective inhibition of human cytomegalovirus gene expression and replication by a ribozyme derived from the catalytic RNA subunit of RNase P from Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 97:5812-5817.
30. Zou H, Lee J, Umamoto S, Kilani AF, Kim J, Trang P, Zhou T, Liu F. 2003. Engineered RNase P ribozymes are efficient in cleaving a human cytomegalovirus mRNA in vitro and are effective in inhibiting viral gene expression and growth in human cells. J. Biol. Chem. 278:37265-37274.
31. Miller AD, Rosman GJ. 1989. Improved retroviral vectors for gene transfer and expression. Biotechniques 7:980-982, 984-986, 989-990.
32. Liu F, Altman S. 1995. Inhibition of viral gene expression by the catalytic RNA subunit of RNase P from Escherichia coli. Genes Dev. 9:471-480.
33. Hanfler J, Kreuzer KA, Laurisch K, Rayes N, Neuhaus P, Schmidt CA, Oettle H. 2003. Quantitation of cytomegalovirus (hCMV) DNA and betaactin DNA by duplex real-time fluorescence PCR in solid organ (liver) transplant recipients. Med. Microbiol. Immunol. 192:197-204.
34. Dunn W, Trang P, Khan U, Zhu J, Liu F. 2001. RNase P-mediated inhibition of cytomegalovirus protease expression and viral DNA encapsidation by oligonucleotide external guide sequences. Proc. Natl. Acad. Sci. U.S.A. 98:14831-14836.
35. Ruder C, Reimer T, Delgado-Martinez I, Hermosilla R, Engelsberg A, Nehring R, Dorken B, Rehm A. 2005. EBAG9 adds a new layer of control on large dense-core vesicle exocytosis via interaction with Snapin. Mol. Biol. Cell 16:1245-1257.
36. Starcevic M, Dell'Angelica EC. 2004. Identification of Snapin and three novel proteins (BLOS1, BLOS2, and BLOS3/reduced pigmentation) as subunits of biogenesis of lysosome-related organelles complex-1 (BLOC-1). J. Biol. Chem. 279:28393-28401.
37. Kieff E, Rickinson AB. 2007. Epstein-Barr virus and its replication, p 2604-2654. In Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B, Straus SEPM(ed), Fields virology, 5th ed. Lippincott William & Wilkins, Philadelphia, PA.
38. Roizman B, Knipe DM, Whitley RJ. 2007. Herpes simplex viruses, p 2503-2601. In Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B, Straus SE PM (ed), Fields virology, 5th ed, vol 2. Lippincott William & Wilkins, Philadelphia, PA.
39. Pari GS, Anders DG. 1993. Eleven loci encoding trans-acting factors are required for transient complementation of human cytomegalovirus oriLyt-dependent DNA replication. J. Virol. 67:6979-6988.
40. Wu CA, Nelson NJ, McGeoch DJ, Challberg MD. 1988. Identification of herpes simplex virus type 1 genes required for origin-dependent DNA synthesis. J. Gen. Virol. 62:435-443.
41. Tortorella D, Gewurz BE, Furman MH, Schust DJ, Ploegh HL. 2000. Viral subversion of the immune system. Annu. Rev. Immunol. 18:861-926.
42. Calder JM, Stow EC, Stow ND. 1992. On the cellular localization of the components of the herpes simplex virus type 1 helicase-primase complex and the viral origin-binding protein. J. Gen. Virol. 73:531-538.