Saposin C protects glucocerebrosidase against α-synuclein inhibition

Biochemistry

Volumn 52, Issue 41, 2013, Pages 7161-7163

  Yap, Thai Leong ^a   Gruschus, James M ^a   Velayati, Arash ^b   Sidransky, Ellen ^b   Lee, Jennifer C ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAUCHER DISEASE; GENETIC RISKS; GLUCOCEREBROSIDASE; LIPID VESICLES; LYSOSOMAL STORAGE DISORDER; PARKINSON DISEASE; SITE-SPECIFIC; SYNUCLEIN;

ENERGY TRANSFER; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

PROTEINS;

ALPHA SYNUCLEIN; GLUCOSYLCERAMIDASE; SAPOSIN C; SPHINGOLIPID ACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; ENZYME ACTIVITY; GBA1 GENE; GENE; GENE MUTATION; GENETIC RISK; HUMAN; LIPID BILAYER; LIPID VESICLE; LYSOSOME STORAGE DISEASE; NITROGEN NUCLEAR MAGNETIC RESONANCE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PARKINSON DISEASE; PRIORITY JOURNAL;

ALPHA-SYNUCLEIN; ENZYME INHIBITORS; GLUCOSYLCERAMIDASE; HUMANS; KINETICS; MODELS, MOLECULAR; MUTATION; PARKINSON DISEASE; PROTEIN BINDING; SAPOSINS;

EID: 84886020944     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi401191v     Document Type: Article

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