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Volumn 6, Issue 6, 2013, Pages 1168-1178

The immune complex CTA1-DD/IgG adjuvant specifically targets connective tissue mast cells through FcγRIIIA and augments anti-HPV immunity after nasal immunization

Author keywords

[No Author keywords available]

Indexed keywords

CD16 ANTIGEN; CTA1 DD; IMMUNOGLOBULIN G; PROTEIN FCGAMMARIIIA; UNCLASSIFIED DRUG; WART VIRUS VACCINE;

EID: 84885977192     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2013.16     Document Type: Article
Times cited : (23)

References (62)
  • 1
    • 84864338756 scopus 로고    scopus 로고
    • Recent progress in mucosal vaccine development: Potential and limitations
    • Lycke, N. Recent progress in mucosal vaccine development: Potential and limitations. Nat. Rev. Immunol. 12, 592-605 (2012).
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 592-605
    • Lycke, N.1
  • 2
    • 34447099136 scopus 로고    scopus 로고
    • Induction of secretory immunity and memory at mucosal surfaces
    • Brandtzaeg, P. Induction of secretory immunity and memory at mucosal surfaces. Vaccine 25, 5467-5484 (2007).
    • (2007) Vaccine , vol.25 , pp. 5467-5484
    • Brandtzaeg, P.1
  • 3
    • 34250331531 scopus 로고    scopus 로고
    • The perfect mix: Recent progress in adjuvant research
    • Guy, B. The perfect mix: Recent progress in adjuvant research. Nat. Rev. Microbiol. 5, 505-517 (2007).
    • (2007) Nat. Rev. Microbiol. , vol.5 , pp. 505-517
    • Guy, B.1
  • 4
    • 36048962961 scopus 로고    scopus 로고
    • How do adjuvants work? Important considerations for new generation adjuvants
    • McKee, A.S., Munks, M.W. & Marrack, P. How do adjuvants work? Important considerations for new generation adjuvants. Immunity 27, 687-690 (2007).
    • (2007) Immunity , vol.27 , pp. 687-690
    • McKee, A.S.1    Munks, M.W.2    Marrack, P.3
  • 6
    • 25444525685 scopus 로고    scopus 로고
    • Enterotoxin-based mucosal adjuvants alter antigen trafficking and induce inflammatory responses in the nasal tract
    • van Ginkel, F.W. et al. Enterotoxin-based mucosal adjuvants alter antigen trafficking and induce inflammatory responses in the nasal tract. Infect. Immun. 73, 6892-6902 (2005).
    • (2005) Infect. Immun. , vol.73 , pp. 6892-6902
    • Van Ginkel, F.W.1
  • 7
    • 79952929452 scopus 로고    scopus 로고
    • From cholera to enterotoxigenic Escherichia coli (ETEC) vaccine development
    • Svennerholm, A.M. From cholera to enterotoxigenic Escherichia coli (ETEC) vaccine development. Indian J. Med. Res. 133, 188-196 (2011).
    • (2011) Indian J. Med. Res. , vol.133 , pp. 188-196
    • Svennerholm, A.M.1
  • 8
    • 43249097624 scopus 로고    scopus 로고
    • Mast cell activators: A new class of highly effective vaccine adjuvants
    • McLachlan, J.B. et al. Mast cell activators: A new class of highly effective vaccine adjuvants. Nat. Med. 14, 536-541 (2008).
    • (2008) Nat. Med. , vol.14 , pp. 536-541
    • McLachlan, J.B.1
  • 9
    • 65649144244 scopus 로고    scopus 로고
    • The mast cell activator compound 48/80 is safe and effective when used as an adjuvant for intradermal immunization with Bacillus anthracis protective antigen
    • McGowen, A.L., Hale, L.P., Shelburne, C.P., Abraham, S.N. & Staats, H.F. The mast cell activator compound 48/80 is safe and effective when used as an adjuvant for intradermal immunization with Bacillus anthracis protective antigen. Vaccine 27, 3544-3552 (2009).
    • (2009) Vaccine , vol.27 , pp. 3544-3552
    • McGowen, A.L.1    Hale, L.P.2    Shelburne, C.P.3    Abraham, S.N.4    Staats, H.F.5
  • 10
    • 79551554495 scopus 로고    scopus 로고
    • Mucosal targeting of a BoNT/A subunit vaccine adjuvanted with a mast cell activator enhances induction of BoNT/A neutralizing antibodies in rabbits
    • Staats, H.F. et al. Mucosal targeting of a BoNT/A subunit vaccine adjuvanted with a mast cell activator enhances induction of BoNT/A neutralizing antibodies in rabbits. PLoS One 6, e16532 (2011).
    • (2011) PLoS One , vol.6
    • Staats, H.F.1
  • 11
    • 0033557754 scopus 로고    scopus 로고
    • Adjuvanticity of the cholera toxin A1-based gene fusion protein, CTA1-DD, is critically dependent on the ADP-ribosyltransferase and Ig-binding activity
    • Agren, L.C., Ekman, L., Lowenadler, B., Nedrud, J.G. & Lycke, N.Y. Adjuvanticity of the cholera toxin A1-based gene fusion protein, CTA1-DD, is critically dependent on the ADP-ribosyltransferase and Ig-binding activity. J. Immunol. 162, 2432-2440 (1999).
    • (1999) J. Immunol. , vol.162 , pp. 2432-2440
    • Agren, L.C.1    Ekman, L.2    Lowenadler, B.3    Nedrud, J.G.4    Lycke, N.Y.5
  • 12
    • 77958195796 scopus 로고    scopus 로고
    • Mucosal adjuvants and long-Term memory development with special focus on CTA1-DD and other ADP-ribosylating toxins
    • Lycke, N. & Bemark, M. Mucosal adjuvants and long-Term memory development with special focus on CTA1-DD and other ADP-ribosylating toxins. Mucosal Immunol. 3, 556-566 (2010).
    • (2010) Mucosal Immunol. , vol.3 , pp. 556-566
    • Lycke, N.1    Bemark, M.2
  • 13
    • 79251591958 scopus 로고    scopus 로고
    • A unique role of the cholera toxin A1-DD adjuvant for long-Term plasma and memory B cell development
    • Bemark, M. et al. A unique role of the cholera toxin A1-DD adjuvant for long-Term plasma and memory B cell development. J. Immunol. 186, 1399-1410 (2011).
    • (2011) J. Immunol. , vol.186 , pp. 1399-1410
    • Bemark, M.1
  • 14
    • 80053536456 scopus 로고    scopus 로고
    • Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant
    • Mattsson, J. et al. Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant. J. Immunol. 187, 3641-3652 (2011).
    • (2011) J. Immunol. , vol.187 , pp. 3641-3652
    • Mattsson, J.1
  • 15
    • 0031569528 scopus 로고    scopus 로고
    • Genetically engineered nontoxic vaccine adjuvant that combines B cell targeting with immunomodulation by cholera toxin A1 subunit
    • Agren, L.C., Ekman, L., Lowenadler, B. & Lycke, N.Y. Genetically engineered nontoxic vaccine adjuvant that combines B cell targeting with immunomodulation by cholera toxin A1 subunit. J. Immunol. 158, 3936-3946 (1997).
    • (1997) J. Immunol. , vol.158 , pp. 3936-3946
    • Agren, L.C.1    Ekman, L.2    Lowenadler, B.3    Lycke, N.Y.4
  • 16
    • 78049358175 scopus 로고    scopus 로고
    • Mast cells contribute to the mucosal adjuvant effect of CTA1-DD after IgG-complex formation
    • Fang, Y., Larsson, L., Mattsson, J., Lycke, N. & Xiang, Z. Mast cells contribute to the mucosal adjuvant effect of CTA1-DD after IgG-complex formation. J. Immunol. 185, 2935-2941 (2010).
    • (2010) J. Immunol. , vol.185 , pp. 2935-2941
    • Fang, Y.1    Larsson, L.2    Mattsson, J.3    Lycke, N.4    Xiang, Z.5
  • 17
    • 36849072350 scopus 로고    scopus 로고
    • The mast cell and allergic diseases: Role in pathogenesis and implications for therapy
    • Brown, J.M., Wilson, T.M. & Metcalfe, D.D. The mast cell and allergic diseases: Role in pathogenesis and implications for therapy. Clin. Exp. Allergy 38, 4-18 (2008).
    • (2008) Clin. Exp. Allergy , vol.38 , pp. 4-18
    • Brown, J.M.1    Wilson, T.M.2    Metcalfe, D.D.3
  • 18
    • 41549112786 scopus 로고    scopus 로고
    • Basophils play a pivotal role in immunoglobulin-Gmediated but not immunoglobulin-E-mediated systemic anaphylaxis
    • Tsujimura, Y. et al. Basophils play a pivotal role in immunoglobulin-Gmediated but not immunoglobulin-E-mediated systemic anaphylaxis. Immunity 28, 581-589 (2008).
    • (2008) Immunity , vol.28 , pp. 581-589
    • Tsujimura, Y.1
  • 19
    • 0033577901 scopus 로고    scopus 로고
    • Modulation of immunoglobulin (Ig)E-mediated systemic anaphylaxis by low-Affinity Fc receptors for IgG
    • Ujike, A. et al. Modulation of immunoglobulin (Ig)E-mediated systemic anaphylaxis by low-Affinity Fc receptors for IgG. J. Exp. Med. 189, 1573-1579 (1999).
    • (1999) J. Exp. Med. , vol.189 , pp. 1573-1579
    • Ujike, A.1
  • 20
    • 84961043202 scopus 로고
    • Passive cutaneous anaphylaxis in the mouse
    • Ovary, Z. Passive cutaneous anaphylaxis in the mouse. J. Immunol. 81, 355-357 (1958).
    • (1958) J. Immunol. , vol.81 , pp. 355-357
    • Ovary, Z.1
  • 21
    • 0017138515 scopus 로고
    • Homologous passive cutaneous anaphylaxis (PCA) in mice and heterologous PCA induced in rats with mouse IgE
    • Braga, F. & Mota, I. Homologous passive cutaneous anaphylaxis (PCA) in mice and heterologous PCA induced in rats with mouse IgE. Immunology 30, 655-669 (1976).
    • (1976) Immunology , vol.30 , pp. 655-669
    • Braga, F.1    Mota, I.2
  • 22
    • 34248226333 scopus 로고    scopus 로고
    • The mast cell IgG receptors and their roles in tissue inflammation
    • Malbec, O. & Daeron, M. The mast cell IgG receptors and their roles in tissue inflammation. Immunol. Rev. 217, 206-221 (2007).
    • (2007) Immunol. Rev. , vol.217 , pp. 206-221
    • Malbec, O.1    Daeron, M.2
  • 23
    • 0033010044 scopus 로고    scopus 로고
    • Fc receptor beta subunit is required for full activation of mast cells through Fc receptor engagement
    • Hiraoka, S. et al. Fc receptor beta subunit is required for full activation of mast cells through Fc receptor engagement. Int. Immunol. 11, 199-207 (1999).
    • (1999) Int. Immunol. , vol.11 , pp. 199-207
    • Hiraoka, S.1
  • 24
    • 77249134192 scopus 로고    scopus 로고
    • Advances in mast cell biology: New understanding of heterogeneity and function
    • Moon, T.C. et al. Advances in mast cell biology: New understanding of heterogeneity and function. Mucosal Immunol. 3, 111-128 (2010).
    • (2010) Mucosal Immunol. , vol.3 , pp. 111-128
    • Moon, T.C.1
  • 25
    • 0026697739 scopus 로고
    • Induction of tumor necrosis factor-Alpha production bymast cells via fc gamma r role of the fc gamma riii gamma subunit
    • Latour, S., Bonnerot, C., Fridman, W.H. & Daeron, M. Induction of tumor necrosis factor-Alpha production bymast cells via Fc gamma R. Role of the Fc gamma RIII gamma subunit. J. Immunol. 149, 2155-2162 (1992).
    • (1992) J. Immunol. , vol.149 , pp. 2155-2162
    • Latour, S.1    Bonnerot, C.2    Fridman, W.H.3    Daeron, M.4
  • 26
    • 33947612179 scopus 로고    scopus 로고
    • FcepsilonRI aggregation promotes survival of connective tissue-like mast cells but not mucosal-like mast cells
    • Ekoff, M., Strasser, A. & Nilsson, G. FcepsilonRI aggregation promotes survival of connective tissue-like mast cells but not mucosal-like mast cells. J. Immunol. 178, 4177-4183 (2007).
    • (2007) J. Immunol. , vol.178 , pp. 4177-4183
    • Ekoff, M.1    Strasser, A.2    Nilsson, G.3
  • 27
    • 0030977229 scopus 로고    scopus 로고
    • Development significance, and heterogeneity of mast cells with particular regard to the mast cell-specific proteases chymase and tryptase
    • Welle, M. Development, significance, and heterogeneity of mast cells with particular regard to the mast cell-specific proteases chymase and tryptase. J. Leukoc. Biol. 61, 233-245 (1997).
    • (1997) J. Leukoc. Biol. , vol.61 , pp. 233-245
    • Welle, M.1
  • 28
    • 0024348298 scopus 로고
    • Heterogeneity of mast cells and phenotypic change between subpopulations
    • Kitamura, Y. Heterogeneity of mast cells and phenotypic change between subpopulations. Annu. Rev. Immunol. 7, 59-76 (1989).
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 59-76
    • Kitamura, Y.1
  • 29
    • 0023514041 scopus 로고
    • Identification, purification, and characterization of a mast cell-Associated cytolytic factor related to tumor necrosis factor
    • Young, J.D., Liu, C.C., Butler, G., Cohn, Z.A. & Galli, S.J. Identification, purification, and characterization of a mast cell-Associated cytolytic factor related to tumor necrosis factor. Proc.Natl. Acad. Sci. USA 84, 9175-9179 (1987).
    • (1987) Proc.Natl. Acad. Sci. USA , vol.84 , pp. 9175-9179
    • Young, J.D.1    Liu, C.C.2    Butler, G.3    Cohn, Z.A.4    Galli, S.J.5
  • 30
    • 0033696744 scopus 로고    scopus 로고
    • Chondroitin sulphate inhibits connective tissue mast cells
    • Theoharides, T.C. et al. Chondroitin sulphate inhibits connective tissue mast cells. Br. J. Pharmacol. 131, 1039-1049 (2000).
    • (2000) Br. J. Pharmacol. , vol.131 , pp. 1039-1049
    • Theoharides, T.C.1
  • 31
    • 0036315811 scopus 로고    scopus 로고
    • Mast cells and macrophages in normal C57/BL/6 mice
    • Gersch, C. et al. Mast cells and macrophages in normal C57/BL/6 mice. Histochem. Cell Biol. 118, 41-49 (2002).
    • (2002) Histochem. Cell Biol. , vol.118 , pp. 41-49
    • Gersch, C.1
  • 32
    • 65249185481 scopus 로고    scopus 로고
    • Murine mast cells secrete a unique profile of cytokines and prostaglandins in response to distinct TLR2 ligands
    • Mrabet-Dahbi, S., Metz, M., Dudeck, A., Zuberbier, T. & Maurer,M.Murine mast cells secrete a unique profile of cytokines and prostaglandins in response to distinct TLR2 ligands. Exp. Dermatol. 18, 437-444 (2009).
    • (2009) Exp. Dermatol. , vol.18 , pp. 437-444
    • Mrabet-Dahbi, S.1    Metz, M.2    Dudeck, A.3    Zuberbier, T.4    Maurer, M.5
  • 33
    • 56149091686 scopus 로고    scopus 로고
    • Correlation between direct ELISA, single epitope-based inhibition ELISA and pseudovirion-based neutralization assay for measuring anti-HPV-16 and anti-HPV-18 antibody response after vaccinationwith the AS04-Adjuvanted HPV-16/18 cervical cancer vaccine
    • Dessy, F.J. et al. Correlation between direct ELISA, single epitope-based inhibition ELISA and pseudovirion-based neutralization assay for measuring anti-HPV-16 and anti-HPV-18 antibody response after vaccinationwith the AS04-Adjuvanted HPV-16/18 cervical cancer vaccine. Hum. Vaccin. 4, 425-434 (2008).
    • (2008) Hum. Vaccin. , vol.4 , pp. 425-434
    • Dessy, F.J.1
  • 34
    • 77950478700 scopus 로고    scopus 로고
    • Trivalent Human Papillomavirus (HPV) VLP vaccine covering HPVtype58can elicit highlevel ofhumoral immunity but also induce immune interference among component types
    • Zhang, T. et al. Trivalent Human Papillomavirus (HPV) VLP vaccine covering HPVtype58can elicit highlevel ofhumoral immunity but also induce immune interference among component types. Vaccine 28, 3479-3487 (2010).
    • (2010) Vaccine , vol.28 , pp. 3479-3487
    • Zhang, T.1
  • 35
    • 77952868792 scopus 로고    scopus 로고
    • Mast cell-orchestrated immunity to pathogens
    • Abraham, S.N. & St John, A.L. Mast cell-orchestrated immunity to pathogens. Nat. Rev. Immunol. 10, 440-452 (2010).
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 440-452
    • Abraham, S.N.1    St John, A.L.2
  • 36
    • 77954115305 scopus 로고    scopus 로고
    • Mast cells in allergy and infection: Versatile effector and regulatory cells in innate and adaptive immunity
    • Galli, S.J. & Tsai, M. Mast cells in allergy and infection: Versatile effector and regulatory cells in innate and adaptive immunity. Eur. J. Immunol. 40, 1843-1851 (2010).
    • (2010) Eur. J. Immunol. , vol.40 , pp. 1843-1851
    • Galli, S.J.1    Tsai, M.2
  • 37
    • 13944249962 scopus 로고    scopus 로고
    • Mast cells in the development of adaptive immune responses
    • Galli, S.J., Nakae, S. & Tsai, M. Mast cells in the development of adaptive immune responses. Nat. Immunol. 6, 135-142 (2005).
    • (2005) Nat. Immunol. , vol.6 , pp. 135-142
    • Galli, S.J.1    Nakae, S.2    Tsai, M.3
  • 38
    • 44349101991 scopus 로고    scopus 로고
    • Immunomodulatory mast cells: Negative, as well as positive, regulators of immunity
    • Galli, S.J., Grimbaldeston, M. & Tsai, M. Immunomodulatory mast cells: Negative, as well as positive, regulators of immunity. Nat. Rev. Immunol. 8, 478-486 (2008).
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 478-486
    • Galli, S.J.1    Grimbaldeston, M.2    Tsai, M.3
  • 39
    • 33746214812 scopus 로고    scopus 로고
    • Mast cells have a pivotal role in TNF-independent lymph node hypertrophy and the mobilization of Langerhans cells in response to bacterial peptidoglycan
    • Jawdat, D.M., Rowden, G. Marshall, J.S.Mast cells have a pivotal role in TNF-independent lymph node hypertrophy and the mobilization of Langerhans cells in response to bacterial peptidoglycan. J. Immunol. 177, 1755-1762 (2006).
    • (2006) J. Immunol. , vol.177 , pp. 1755-1762
    • Jawdat, D.M.1    Rowden, G.2    Marshall, J.S.3
  • 40
    • 33646062612 scopus 로고    scopus 로고
    • Mast cell-Associated TNF promotes dendritic cell migration
    • Suto, H. et al. Mast cell-Associated TNF promotes dendritic cell migration. J. Immunol. 176, 4102-4112 (2006).
    • (2006) J. Immunol. , vol.176 , pp. 4102-4112
    • Suto, H.1
  • 41
    • 34547949557 scopus 로고    scopus 로고
    • Mast cells are crucial for early inflammation, migration of Langerhans cells, and CTL responses following topical application of TLR7 ligand in mice
    • Heib, V. et al. Mast cells are crucial for early inflammation, migration of Langerhans cells, and CTL responses following topical application of TLR7 ligand in mice. Blood 110, 946-953 (2007).
    • (2007) Blood , vol.110 , pp. 946-953
    • Heib, V.1
  • 42
    • 72649083886 scopus 로고    scopus 로고
    • Mast cells augment adaptive immunity by orchestrating dendritic cell trafficking through infected tissues
    • Shelburne, C.P. et al. Mast cells augment adaptive immunity by orchestrating dendritic cell trafficking through infected tissues. Cell Host Microbe 6, 331-342 (2009).
    • (2009) Cell Host Microbe , vol.6 , pp. 331-342
    • Shelburne, C.P.1
  • 43
    • 77949907978 scopus 로고    scopus 로고
    • Mast cells, histamine, and IL-6 regulate the selective influx of dendritic cell subsets into an inflamed lymph node
    • Dawicki, W., Jawdat, D.W., Xu, N. & Marshall, J.S. Mast cells, histamine, and IL-6 regulate the selective influx of dendritic cell subsets into an inflamed lymph node. J. Immunol. 184, 2116-2123 (2010).
    • (2010) J. Immunol. , vol.184 , pp. 2116-2123
    • Dawicki, W.1    Jawdat, D.W.2    Xu, N.3    Marshall, J.S.4
  • 44
    • 0027471975 scopus 로고
    • Intracellular degradation of Fc gamma RIII in mouse bone marrow culture-derived progenitor mast cells prevents its surface expression and associated function
    • Lobell, R.B., Arm, J.P., Raizman, M.B., Austen, K.F. & Katz, H.R. Intracellular degradation of Fc gamma RIII in mouse bone marrow culture-derived progenitor mast cells prevents its surface expression and associated function. J. Biol. Chem. 268, 1207-1212 (1993).
    • (1993) J. Biol. Chem. , vol.268 , pp. 1207-1212
    • Lobell, R.B.1    Arm, J.P.2    Raizman, M.B.3    Austen, K.F.4    Katz, H.R.5
  • 45
    • 0023904815 scopus 로고
    • The effect of compound 48/80 and of electrical field stimulation on mast cells in the isolated mouse stomach
    • Stanovnik, L., Logonder-Mlinsek, M. & Erjavec, F. The effect of compound 48/80 and of electrical field stimulation on mast cells in the isolated mouse stomach. Agents Actions 23, 300-303 (1988).
    • (1988) Agents Actions , vol.23 , pp. 300-303
    • Stanovnik, L.1    Logonder-Mlinsek, M.2    Erjavec, F.3
  • 46
    • 0018770516 scopus 로고
    • Long term increase of mucosal mast cells in the rat induced by administration of compound 48/80
    • Enerback, L. & Lowhagen, G.B. Long term increase of mucosal mast cells in the rat induced by administration of compound 48/80. Cell Tissue Res. 198, 209-215 (1979).
    • (1979) Cell Tissue Res. , vol.198 , pp. 209-215
    • Enerback, L.1    Lowhagen, G.B.2
  • 47
    • 2942731608 scopus 로고    scopus 로고
    • TLR3-, TLR7-, and TLR9-mediated production of proinflammatory cytokines and chemokines from murine connective tissue type skin-derived mast cells but not from bone marrow-derived mast cells
    • Matsushima, H., Yamada, N., Matsue, H. & Shimada, S. TLR3-, TLR7-, and TLR9-mediated production of proinflammatory cytokines and chemokines from murine connective tissue type skin-derived mast cells but not from bone marrow-derived mast cells. J. Immunol. 173, 531-541 (2004).
    • (2004) J. Immunol. , vol.173 , pp. 531-541
    • Matsushima, H.1    Yamada, N.2    Matsue, H.3    Shimada, S.4
  • 48
    • 37549036732 scopus 로고    scopus 로고
    • Fcgamma receptors as regulators of immune responses
    • Nimmerjahn, F. & Ravetch, J.V. Fcgamma receptors as regulators of immune responses. Nat. Rev. Immunol. 8, 34-47 (2008).
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 34-47
    • Nimmerjahn, F.1    Ravetch, J.V.2
  • 49
    • 34548229364 scopus 로고    scopus 로고
    • FcRn: The neonatal Fc receptor comes of age
    • Roopenian, D.C. & Akilesh, S. FcRn: The neonatal Fc receptor comes of age. Nat. Rev. Immunol. 7, 715-725 (2007).
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 715-725
    • Roopenian, D.C.1    Akilesh, S.2
  • 50
    • 33750699277 scopus 로고    scopus 로고
    • Pulmonary administration of therapeutic proteins using an immunoglobulin transport pathway
    • Bitonti, A.J. & Dumont, J.A. Pulmonary administration of therapeutic proteins using an immunoglobulin transport pathway. Adv. Drug Deliv. Rev. 58, 1106-1118 (2006).
    • (2006) Adv. Drug Deliv. Rev. , vol.58 , pp. 1106-1118
    • Bitonti, A.J.1    Dumont, J.A.2
  • 51
    • 26644434124 scopus 로고    scopus 로고
    • Nasal mucoadhesive drug delivery: Background, applications, trends and future perspectives
    • Ugwoke, M.I., Agu, R.U., Verbeke, N. & Kinget, R. Nasal mucoadhesive drug delivery: Background, applications, trends and future perspectives. Adv. Drug Deliv. Rev. 57, 1640-1665 (2005).
    • (2005) Adv. Drug Deliv. Rev. , vol.57 , pp. 1640-1665
    • Ugwoke, M.I.1    Agu, R.U.2    Verbeke, N.3    Kinget, R.4
  • 52
    • 85185124485 scopus 로고    scopus 로고
    • WHO/ICO Information Centre on HPV and Cervical Cancer
    • WHO/ICO Information Centre on HPV and Cervical Cancer. HPV and cervical cancer in the 2007 report. Vaccine 25 (Suppl 3), C1-230 (2007).
    • (2007) HPV and cervical cancer in the 2007 report. Vaccine , vol.25 , Issue.SUPPL.3
  • 53
    • 34547467742 scopus 로고    scopus 로고
    • Humoral and cellular immune responses to airway immunization ofmice with human papillomavirus type 16 virus-like particles and mucosal adjuvants
    • Revaz, V. et al. Humoral and cellular immune responses to airway immunization ofmice with human papillomavirus type 16 virus-like particles and mucosal adjuvants. Antiviral Res. 76, 75-85 (2007).
    • (2007) Antiviral Res. , vol.76 , pp. 75-85
    • Revaz, V.1
  • 54
    • 20244382261 scopus 로고    scopus 로고
    • A human papillomavirus type 16 vaccine by oral delivery of L1 protein
    • Sasagawa, T. et al. A human papillomavirus type 16 vaccine by oral delivery of L1 protein. Virus Res. 110, 81-90 (2005).
    • (2005) Virus Res. , vol.110 , pp. 81-90
    • Sasagawa, T.1
  • 55
    • 18844377157 scopus 로고    scopus 로고
    • Immune responses induced by lower airway mucosal immunisation with a human papillomavirus type 16 virus-like particle vaccine
    • Nardelli-Haefliger, D. et al. Immune responses induced by lower airway mucosal immunisation with a human papillomavirus type 16 virus-like particle vaccine. Vaccine 23, 3634-3641 (2005).
    • (2005) Vaccine , vol.23 , pp. 3634-3641
    • Nardelli-Haefliger, D.1
  • 56
    • 0032826809 scopus 로고    scopus 로고
    • Mucosal but not parenteral immunization with purified human papillomavirus type 16 virus-like particles induces neutralizing titers of antibodies throughout the estrous cycle of mice
    • Nardelli-Haefliger, D. et al. Mucosal but not parenteral immunization with purified human papillomavirus type 16 virus-like particles induces neutralizing titers of antibodies throughout the estrous cycle of mice. J. Virol. 73, 9609-9613 (1999).
    • (1999) J. Virol. , vol.73 , pp. 9609-9613
    • Nardelli-Haefliger, D.1
  • 57
    • 79958137861 scopus 로고    scopus 로고
    • Aerosol delivery of virus-like particles to the genital tract induces local and systemic antibody responses
    • Hunter, Z., Tumban, E., Dziduszko, A. & Chackerian, B. Aerosol delivery of virus-like particles to the genital tract induces local and systemic antibody responses. Vaccine 29, 4584-4592 (2011).
    • (2011) Vaccine , vol.29 , pp. 4584-4592
    • Hunter, Z.1    Tumban, E.2    Dziduszko, A.3    Chackerian, B.4
  • 58
    • 18244396367 scopus 로고    scopus 로고
    • Effect of the menstrual cycle on immunological parameters in the human female reproductive tract
    • Wira, C., Fahey, J.,Wallace, P. & Yeaman, G. Effect of the menstrual cycle on immunological parameters in the human female reproductive tract. J. Acquir. Immune Defic. Syndr. 38 (Suppl 1), S34-S36 (2005).
    • (2005) J. Acquir. Immune Defic. Syndr. , vol.38 , Issue.SUPPL.1
    • Wira, C.1    Fahey, J.2    Wallace, P.3    Yeaman, G.4
  • 59
    • 0037384980 scopus 로고    scopus 로고
    • Progesterone increases susceptibility and decreases immune responses to genital herpes infection
    • Kaushic, C., Ashkar, A.A., Reid, L.A. & Rosenthal, K.L. Progesterone increases susceptibility and decreases immune responses to genital herpes infection. J. Virol. 77, 4558-4565 (2003).
    • (2003) J. Virol. , vol.77 , pp. 4558-4565
    • Kaushic, C.1    Ashkar, A.A.2    Reid, L.A.3    Rosenthal, K.L.4
  • 60
    • 79959754041 scopus 로고    scopus 로고
    • Mast cells promote Th1 and Th17 responses by modulating dendritic cell maturation and function
    • Dudeck, A., Suender, C.A., Kostka, S.L., von Stebut, E. & Maurer,M. Mast cells promote Th1 and Th17 responses by modulating dendritic cell maturation and function. Eur. J. Immunol. 41, 1883-1893 (2011).
    • (2011) Eur. J. Immunol. , vol.41 , pp. 1883-1893
    • Dudeck, A.1    Suender, C.A.2    Kostka, S.L.3    Von Stebut, E.4    Maurer, M.5
  • 61
    • 0033769882 scopus 로고    scopus 로고
    • IgE receptor-mediated release of nerve growth factor by mast cells
    • Xiang, Z. & Nilsson, G. IgE receptor-mediated release of nerve growth factor by mast cells. Clin. Exp. Allergy 30, 1379-1386 (2000).
    • (2000) Clin. Exp. Allergy , vol.30 , pp. 1379-1386
    • Xiang, Z.1    Nilsson, G.2
  • 62
    • 33748799966 scopus 로고    scopus 로고
    • Readministration of IgE is required for repeated passive cutaneous anaphylaxis in mice
    • Xiang, Z., Moller, C. & Nilsson, G. Readministration of IgE is required for repeated passive cutaneous anaphylaxis in mice. Int. Arch. Allergy Immunol. 141, 168-171 (2006).
    • (2006) Int. Arch. Allergy Immunol. , vol.141 , pp. 168-171
    • Xiang, Z.1    Moller, C.2    Nilsson, G.3


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