Scorpiand-like azamacrocycles prevent the chronic establishment of Trypanosoma cruzi in a murine model

European Journal of Medicinal Chemistry

Volumn 70, Issue , 2013, Pages 189-198

  Olmo, Francisco ^a   Marín, Clotilde ^a   Clares, M Paz ^b   Blasco, Salvador ^b   Albelda, M Teresa ^b   Soriano, Conxa ^b   Gutiérrez Sánchez, Ramón ^a   Arrebola Vargas, Francisco ^a   García España, Enrique ^b   Sánchez Moreno, Manuel ^a  

^a UNIVERSITY OF GRANADA   (Spain)

^b UNIVERSITY OF VALENCIA   (Spain)

Author keywords

In vivo activity; Synthetic aza scorpiand; Trypanocidal activity; Trypanosoma cruzi

Indexed keywords

ANTITRYPANOSOMAL AGENT; BENZNIDAZOLE; COPPER ZINC SUPEROXIDE DISMUTASE; IRON SUPEROXIDE DISMUTASE; MACROCYCLIC COMPOUND; MANGANESE SUPEROXIDE DISMUTASE;

AEROBIC METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DAMAGE; CHAGAS DISEASE; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; ENERGY RESOURCE; ENZYME INHIBITION; EPIMASTIGOTE; ESCHERICHIA COLI; FEMALE; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; INFECTION; INFECTION RATE; MOUSE; NONHUMAN; PARASITE LOAD; PROTON NUCLEAR MAGNETIC RESONANCE; TRYPANOSOMA CRUZI; VERO CELL;

IN VIVO ACTIVITY; SYNTHETIC AZA-SCORPIAND; TRYPANOCIDAL ACTIVITY; TRYPANOSOMA CRUZI;

ANIMALS; ANTIPROTOZOAL AGENTS; AZA COMPOUNDS; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; ESCHERICHIA COLI; FEMALE; HUMANS; LIGANDS; MACROCYCLIC COMPOUNDS; MICE; MICE, INBRED BALB C; MOLECULAR STRUCTURE; SUPEROXIDE DISMUTASE; TRYPANOSOMA CRUZI; VERO CELLS;

EID: 84885969991     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.09.048     Document Type: Article

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