In vitro activity of scorpiand-like azamacrocycle derivatives in promastigotes and intracellular amastigotes of Leishmania infantum and Leishmania braziliensis

European Journal of Medicinal Chemistry

Volumn 62, Issue , 2013, Pages 466-477

  Marín, Clotilde ^a   Clares, M Paz ^b   Ramírez Macías, Inmaculada ^a   Blasco, Salvador ^b   Olmo, Francisco ^a   Soriano, Conxa ^b   Verdejo, Begoña ^b   Rosales, María José ^a   Gomez Herrera, David ^a   García España, Enrique ^b   Sánchez Moreno, Manuel ^a  

^a UNIVERSITY OF GRANADA   (Spain)

^b UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Antileishmanial activity; Leishmania braziliensis; Leishmania infantum; SOD inhibition; Synthetic aza scorpiand

Indexed keywords

6 (2 AMINOETHYL) 3,6,9 TRIAZA 1 (2,6)PYRIDINECYCLODECAPHANE; 6 (3,7 DIAZAHEPTYL) 3,6,9 TRIAZA 1 (2,6)PYRIDINECYCLODECAPHANE; 6 [4 (1 NAPHTHYL) 3 AZABUTYL] 3,6,9 TRIAZA 1 (2,6)PYRIDINECYCLODECAPHANE; 6 [4 (2 PYRIDYL) 3 AZABUTYL] 3,6,9 TRIAZA 1 (2,6)PYRIDINECYCLODECAPHANE; 6 [4 (3 PYRIDYL) 3 AZABUTYL] 3,6,9 TRIAZA 1 (2,6)PYRIDINECYCLODECAPHANE; ANTILEISHMANIAL AGENT; COPPER ZINC SUPEROXIDE DISMUTASE; IRON SUPEROXIDE DISMUTASE; MACROCYCLIC COMPOUND; MANGANESE SUPEROXIDE DISMUTASE; MEGLUMINE ANTIMONATE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

AMASTIGOTE; ANIMAL CELL; ANTIPROTOZOAL ACTIVITY; ARTICLE; CATABOLISM; CELL DAMAGE; CYTOTOXICITY; ESCHERICHIA COLI; FEMALE; IN VITRO STUDY; LEISHMANIA BRAZILIENSIS; LEISHMANIA INFANTUM; LEISHMANIASIS; MOUSE; NONHUMAN; PROMASTIGOTE; PROTON NUCLEAR MAGNETIC RESONANCE; TRANSMISSION ELECTRON MICROSCOPY;

ANTIPROTOZOAL AGENTS; AZA COMPOUNDS; DOSE-RESPONSE RELATIONSHIP, DRUG; LEISHMANIA BRAZILIENSIS; LEISHMANIA INFANTUM; MACROCYCLIC COMPOUNDS; MOLECULAR STRUCTURE; PARASITIC SENSITIVITY TESTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84873417562     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.01.001     Document Type: Article

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