Pharmacological profile of the selective β3-adrenoceptor agonist mirabegron in cynomolgus monkeys

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 386, Issue 11, 2013, Pages 1001-1008

  Hatanaka, Toshiki ^a   Ukai, Masashi ^a   Watanabe, Mai ^a   Someya, Akiyoshi ^a   Ohtake, Akiyoshi ^a   Suzuki, Masanori ^a   Ueshima, Koji ^a   Sato, Shuichi ^a   Masuda, Noriyuki ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

3 adrenoceptor; Cynomolgus monkey; Mirabegron; Overactive bladder

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BETA 3 ADRENERGIC RECEPTOR; CYCLIC AMP; MESSENGER RNA; MIRABEGRON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLADDER FUNCTION; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG POTENCY; DRUG SELECTIVITY; FEMALE; GENE EXPRESSION; MACACA FASCICULARIS; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; OVERACTIVE BLADDER; POLYMERASE CHAIN REACTION; QUANTITATIVE ANALYSIS; URINARY FREQUENCY; URINE VOLUME;

ACETANILIDES; ADRENERGIC BETA-3 RECEPTOR AGONISTS; ANIMALS; CHO CELLS; CRICETULUS; CYCLIC AMP; FEMALE; MACACA FASCICULARIS; MUSCLE CONTRACTION; MUSCLE, SMOOTH; RECEPTORS, ADRENERGIC, BETA-3; RNA, MESSENGER; THIAZOLES; URINARY BLADDER;

EID: 84885953638     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-013-0900-1     Document Type: Article

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