Effects of ritobegron (KUC-7483), a novel selective β3- adrenoceptor agonist, on bladder function in cynomolgus monkey

Journal of Pharmacology and Experimental Therapeutics

Volumn 342, Issue 1, 2012, Pages 163-168

  Maruyama, Itaru ^a   Tatemichi, Satoshi ^a   Goi, Yoshiaki ^a   Maruyama, Kazuyasu ^a   Hoyano, Yuji ^a   Yamazaki, Yoshinobu ^a   Kusama, Hiroshi ^a  

^a KISSEI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3 (2 ALLYLPHENOXY) 1 [1,2,3,4 TETRAHYDRONAPHTH 1 YLAMINO] 2 PROPANOL; 5 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL] 1,3 BENZODIOXOLE 2,2 DICARBOXYLIC ACID; BETA 3 ADRENERGIC RECEPTOR BLOCKING AGENT; ISOPRENALINE; RITOBEGRON; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLADDER FUNCTION; BLADDER PRESSURE; CARDIOVASCULAR PARAMETERS; CONCENTRATION RESPONSE; DRUG DOSE COMPARISON; DRUG MECHANISM; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; FEMALE; HEART ATRIUM; HEART RATE; IN VITRO STUDY; IN VIVO STUDY; ISOLATED BLADDER; ISOLATED ORGAN; MACACA FASCICULARIS; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; OVERACTIVE BLADDER; PRIORITY JOURNAL; REST; SMOOTH MUSCLE RELAXATION; SMOOTH MUSCLE TONE; TISSUE SPECIFICITY; TRACHEA;

ACETATES; ADRENERGIC BETA-3 RECEPTOR AGONISTS; ADRENERGIC BETA-3 RECEPTOR ANTAGONISTS; ANIMALS; BLOOD PRESSURE; FEMALE; HEART ATRIA; HEART RATE; MACACA FASCICULARIS; MALE; MUSCLE CONTRACTION; MUSCLE RELAXATION; P-HYDROXYAMPHETAMINE; TRACHEA; URINARY BLADDER; URINARY BLADDER, OVERACTIVE;

EID: 84862503635     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.191783     Document Type: Article

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