Self-assemblies of pH-activatable PEGylated multiarm poly(lactic acid-co-glycolic acid)-doxorubicin prodrugs with improved long-term antitumor efficacies

Macromolecular Bioscience

Volumn 13, Issue 10, 2013, Pages 1300-1307

  Ding, Jianxun ^a   Li, Di ^a   Zhuang, Xiuli ^a   Chen, Xuesi ^a  

^a CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY   (China)

Author keywords

Amphiphiles; Malignancy therapy; PH activatable; Prodrug; Self assembly

Indexed keywords

ANTI-PROLIFERATIVE ACTIVITIES; ANTI-TUMOR EFFICACY; HYDRODYNAMIC RADIUS; MALIGNANCY THERAPY; PH-ACTIVATABLE; POLY(LACTIC ACID-CO-GLYCOLIC ACID); POLYMERIC DRUG DELIVERY SYSTEM; PRODRUGS;

AMPHIPHILES; CHEMOTHERAPY; CONDENSATION REACTIONS; COPOLYMERS; CRITICAL MICELLE CONCENTRATION; DRUG DELIVERY; LACTIC ACID; MICELLES; POLYETHYLENE OXIDES; SELF ASSEMBLY;

POLYETHYLENE GLYCOLS;

COPOLYMER; DOXORUBICIN; DRUG RELASE; POLY(ETHYLENE GLYCOL) POLY(LACTIC ACID CO GLYCOLIC ACID); UNCLASSIFIED DRUG;

ARTICLE; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG RELEASE; DRUG STRUCTURE; HUMAN; HUMAN CELL; IN VITRO STUDY; MICELLE;

AMPHIPHILES; MALIGNANCY THERAPY; PH-ACTIVATABLE; PRODRUG; SELF-ASSEMBLY;

CELL LINE, TUMOR; CELL SURVIVAL; DOXORUBICIN; DRUG DELIVERY SYSTEMS; ENDOSOMES; HUMANS; HYDROGEN-ION CONCENTRATION; LACTIC ACID; MICELLES; POLYGLYCOLIC ACID; PRODRUGS;

EID: 84885947911     PISSN: 16165187     EISSN: 16165195     Source Type: Journal    
DOI: 10.1002/mabi.201300160     Document Type: Article

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