Influence of coupling bonds on the anti-tumor activity of polymer-pirarubicin conjugates

European Journal of Pharmaceutical Sciences

Volumn 46, Issue 5, 2012, Pages 329-335

  Mo, Guojun ^a,b   Hu, Xiuli ^a   Liu, Shi ^a   Yue, Jun ^a,b   Wang, Rui ^a,b   Huang, Yubin ^a   Jing, Xiabin ^a  

^a CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Amide; Ester; Hydrazone; Pirarubicin; Polymer drug conjugate

Indexed keywords

AMIDE; ESTER; HYDRAZONE DERIVATIVE; PIRARUBICIN; POLY(ETHYLENE GLYCOL)BLOCK POLY(LACTIDECO 2 METHYL 2 CARBOXYL PROPYLENE CARBONATE); POLYMER; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST ADENOCARCINOMA; CANCER CELL; CELL TRANSPORT; CONTROLLED STUDY; CROSS COUPLING REACTION; CYTOTOXICITY; DRUG BINDING; DRUG CONJUGATION; DRUG FATALITY; DRUG UPTAKE; IN VITRO STUDY; MICELLE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ADENOCARCINOMA; AMIDES; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BIOLOGICAL TRANSPORT; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; CHEMISTRY, PHARMACEUTICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; ESTERS; FEMALE; HYDRAZONES; HYDROGEN-ION CONCENTRATION; KINETICS; MICE; MICE, INBRED BALB C; MICELLES; PARTICLE SIZE; POLYESTERS; POLYETHYLENE GLYCOLS; POLYMERS; PROPANE; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL;

EID: 84862814290     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2012.02.013     Document Type: Article

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