Lysine biosynthesis in microbes: Relevance as drug target and prospects for β-lactam antibiotics production

Applied Microbiology and Biotechnology

Volumn 97, Issue 9, 2013, Pages 3763-3772

  Fazius, Felicitas ^a   Zaehle, Christoph ^a   Brock, Matthias ^a,b  

^a HANS KNÖLL INSTITUTE   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Aconitase; Antibiotics; Homoaconitase; Meso diaminopimelate; Peptidoglycan; aminioadipate

Indexed keywords

AMINO ACIDS; BACTERIA; BIOCHEMISTRY; BIOSYNTHESIS; FUNGI; REACTION INTERMEDIATES;

ACONITASE; BIOCHEMICAL REACTIONS; EUKARYOTIC MICROORGANISMS; HOMOACONITASE; INDUSTRIAL FERMENTATION; ISOMERISATION REACTIONS; MESO-DIAMINOPIMELATE; PEPTIDOGLYCANS;

ANTIBIOTICS;

2 AMINOADIPIC ACID; ANTIFUNGAL AGENT; BETA LACTAM ANTIBIOTIC; CEPHALOSPORIN DERIVATIVE; DIAMINOPIMELIC ACID; LYSINE; PENICILLIN DERIVATIVE; ACONITATE HYDRATASE; ANTIINFECTIVE AGENT; BETA LACTAM; HOMOACONITATE HYDRATASE; HYDROLYASE; PEPTIDOGLYCAN;

ANTIBIOTICS; BACTERIUM; BIOCHEMICAL COMPOSITION; ENZYME ACTIVITY; FUNGUS;

DRUG MANUFACTURE; DRUG SYNTHESIS; DRUG TARGETING; ENZYME SYNTHESIS; FILAMENTOUS FUNGUS; ISOMERIZATION; SHORT SURVEY; SIGNAL TRANSDUCTION; ARTICLE; BIOSYNTHESIS; METABOLISM; METHODOLOGY; MICROBIOLOGY;

BACTERIA (MICROORGANISMS); EUKARYOTA; FUNGI;

ACONITATE HYDRATASE; ANTI-BACTERIAL AGENTS; BETA-LACTAMS; DIAMINOPIMELIC ACID; HYDRO-LYASES; INDUSTRIAL MICROBIOLOGY; LYSINE; PEPTIDOGLYCAN;

EID: 84885922761     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-013-4805-1     Document Type: Short Survey

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